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Inhibition of immune checkpoints PD-1, CTLA-4, and IDO1 coordinately induces immune-mediated liver injury in mice

Contributions Conceptualization: Timothy Affolter, Derek W. Bartlett, Changhua Ji. 16 / 19 Data curation: Timothy Affolter, Heather P. Llewellyn, Derek W. Bartlett, Qing Zong, Shuhua Xia. Formal analysis ... : Timothy Affolter, Heather P. Llewellyn, Derek W. Bartlett, Shuhua Xia. Funding acquisition: Timothy Affolter, Vince Torti, Changhua Ji. Investigation: Timothy Affolter, Heather P. Llewellyn, Derek W

Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging

Derek W. Bartlett 0 Mark E. Davis 0 0 Chemical Engineering, California Institute of Technology , Pasadena, CA 91125, USA Small interfering RNA (siRNA) molecules are potent effectors of post