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Search: authors:"Donald P. McManus"

12 papers found.
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A Systematic Review of Preventive Health Educational Videos Targeting Infectious Diseases in Schoolchildren

Research Scholarship. Darren J. Gray is an Australian Research Council Fellow. Donald P. McManus is a National Health and Medical Research Council of Australia Senior Principal Research Fellow. Disclosure ... , Queensland, Australia, E-mail: . Donald P. McManus, Queensland Institute of Medical Research, Herston, Queensland, Australia, E-mail: .

SHORT REPORT: INADEQUACY OF YAKS AS HOSTS FOR THE SHEEP DOG STRAIN OF ECHINOCOCCUS GRANULOSUS OR FOR E. MULTILOCULARIS

Hydatid disease (echinococcosis) has a two-host cycle involving the domestic dog and grazing animals. Humans are also infected by the dog. Both unilocular (Echinococcus granulosus in yaks, sheep, and goats) and multilocular (alveolar) (E. multilocularis in hares and rodents) hydatids are common in western Sichuan in the People’s Republic of China. Humans and dogs are equally...

CD4+ T-CELL COUNTS, CD4+/CD8+ T-CELL COUNT RATIOS, AND ANTIBODY LEVELS IN MIGRANT FISHERMEN INFECTED WITH SCHISTOSOMA JAPONICUM IN THE DONGTING LAKE, CHINA

In this study, CD4+ and CD8+ T cells and antibody levels were measured in 94 migrant fishermen infected with Schistosoma japonicum from Dongting Lake, China. Prevalence among these fishermen was high (63.8%), with a mean infection intensity of 61.4 ± 3.8 epg, and included a high proportion of individuals (39.4%) with substantial parenchymal fibrosis (stages ≥ 2/3). The CD4+/CD8...

Artemether Treatment of Prepatent Schistosoma japonicum Induces Resistance to Reinfection in Association with Reduced Pathology

Artemether (ART) is a well-described antimalarial with efficacy against juvenile schistosomes, with 7-day-old schistosomula being particularly susceptible. Both ART-affected worms and parasites developing from irradiated cercariae die at similar times after infection. Our aim was to determine if ART treatment of prepatent schistosomiasis japonica may result in the generation of a...

ANTIGEN-SPECIFIC ANTIBODY ISOTYPE PATTERNS TO SCHISTOSOMA JAPONICUM RECOMBINANT AND NATIVE ANTIGENS IN A DEFINED POPULATION IN LEYTE, THE PHILIPPINES

We describe antibody isotype patterns resulting from Schistosoma japonicum infection among 155 individuals 5–76 years old from a community in Leyte, The Philippines. Their exposure, infection, and reinfection status had been observed in a previously described water contact study used to categorically classify them as putative resistant or susceptible individuals. Antigens tested...

A Cluster-Randomized Bovine Intervention Trial against Schistosoma japonicum in the People’s Republic of China: Design and Baseline Results

Prevention, 207 Rui Jin Er Lu, Shanghai 200005, Peoples Republic of China. Donald P. McManus, Australian Centre for International and Tropical Health and Nutrition, The University of Queensland and The

SHORT REPORT: ECHINOCOCCUS GRANULOSUS FROM XINJIANG, PR CHINA: cDNAS ENCODING THE EG95 VACCINE ANTIGEN ARE EXPRESSED IN DIFFERENT LIFE CYCLE STAGES AND ARE CONSERVED IN THE ONCOSPHERE

, Urumqi, Xinjiang, China 1 Authors' addresses: Jun Li, Hong You, Alex Loukas, and Donald P. McManus. Molecular Parasitology Laboratory, Australian Centre for International and Tropical Health and Nutrition

Short report: molecular genetic characterization of an unusually severe case of hydatid disease in Alaska caused by the cervid strain of Echinococcus granulosus.

Distinct Echinococcus granulosus life cycle patterns have been described in North America: domestic and sylvatic. Gene sequences of the sylvatic E. granulosus indicate that it represents a separate variant. Case-based data have suggested that the course of sylvatic disease is less severe than that of domestic disease, which led to the recommendation to treat cystic echinococcosis...

A DRUG-BASED INTERVENTION STUDY ON THE IMPORTANCE OF BUFFALOES FOR HUMAN SCHISTOSOMA JAPONICUM INFECTION AROUND POYANG LAKE, PEOPLE’S REPUBLIC OF CHINA

Gray, Donald P. McManus, and Gail M. Williams, Australian Centre for International and Tropical Health and Nutrition, University of Queensland and Queensland Institute of Medical Research, 300 Herston ... Road, Brisbane, Queensland 4029, Australia. An Ning and Honggen Chen, Jiangxi Provincial Institute of Parasitic Reprint requests: Donald P. McManus, Molecular Parasitology Laboratory, Queensland

Two atypical cases of cystic echinococcosis (Echinococcus granulosus) in Alaska, 1999.

0 LOUISA J. CASTRODALE , MICHAEL BELLER, JOSEPH F. WILSON, PETER M. SCHANTZ, DONALD P. MCMANUS, LI-HUA ZHANG, FRANC G. FALLICO 1 Authors' addresses: Louisa J. Castrodale and Michael Beller, Sec- tion

UNIQUE FAMILY CLUSTERING OF HUMAN ECHINOCOCCOSIS CASES IN A CHINESE COMMUNITY

of interest. Reprint requests: Donald P. McManus, Molecular Parasitology Laboratory, Queensland Institute of Medical Research, 300 Herston Road, Brisbane, Queensland 4006, Australia, Telephone: 61-7

A baseline study of importance of bovines for human Schistosoma japonicum infections around Poyang Lake, China: villages studied and snail sampling strategy.

An epidemiologic survey among four administrative villages around Poyang Lake, in Jiangxi Province, China (two experimental and two controls) is being conducted to determine if bovine infections are responsible for the persistence of human schistosomiasis transmission on Yangtze River marshlands. A previously published paper presented the experimental design and baseline data for...