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6 papers found.
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Expression of minichromosome maintenance genes in renal cell carcinoma

Expression of minichromosome maintenance genes in renal cell carcinoma Hongbin Zhong,1,* Bin Chen,1,* Henrique Neves,2 Jinchun Xing,1 Youxin Ye,1 Ying Lin,1 Guohong Zhuang,3 Shu-Dong Zhang,4 Jiyi

A gene-signature progression approach to identifying candidate small-molecule cancer therapeutics with connectivity mapping

, UK 1 Centre for Cancer Research and Cell Biology (CCRCB), Queen's University Belfast , Belfast , UK 2 Peter W. Hamilton and Shu-Dong Zhang are joint senior authors 3 Scientific Computing Department

The prognostic significance of DAPK1 in bladder cancer

Bladder cancer is one of the leading causes of cancer-related death in men, however, there was only limited effective treatment for invasive bladder cancer. DAPK1 has been shown to play important role in apoptosis and autophagy to suppress cancer progression. Previous results have shown that DAPK1 promoter was hypermethylated in the majority of bladder cancer specimens, however...

QUADrATiC: scalable gene expression connectivity mapping for repurposing FDA-approved therapeutics

contributor. Ken I. Mills and Shu-Dong Zhang are joint senior authors Background: Gene expression connectivity mapping has proven to be a powerful and flexible tool for research. Its application has been shown

cudaMap: a GPU accelerated program for gene expression connectivity mapping

Darragh G McArt 0 Peter Bankhead 0 Philip D Dunne Manuel Salto-Tellez Peter Hamilton Shu-Dong Zhang 0 Equal contributors Centre for Cancer Research and Cell Biology (CCRCB), Queen's University

Gene Expression Meta-Analysis Identifies VDAC1 as a Predictor of Poor Outcome in Early Stage Non-Small Cell Lung Cancer

Background The bioenergetic status of non-small cell lung cancer correlates with tumour aggressiveness. The voltage dependent anion channel type 1 (VDAC1) is a component of the mitochondrial permeability transition pore, regulates mitochondrial ATP/ADP exchange suggesting that its over-expression could be associated with energy dependent processes including increased...