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The application of nano-enrichment in CTC detection and the clinical significance of CTCs in non-small cell lung cancer (NSCLC) treatment

detecting EGFR E19del/L858R mutations. (PDF) Author Contributions Conceptualization: Tengteng Wei, Donglin Zhu, Rongming Shen. Data curation: Tengteng Wei, Donglin Zhu. Formal analysis: Tengteng Wei ... , Donglin Zhu, Yong Yang. Investigation: Tengteng Wei, Donglin Zhu, Yong Yang, Guangda Yuan, Hongya Xie. Methodology: Tengteng Wei, Donglin Zhu, Rongming Shen. Project administration: Tengteng Wei, Rongming

Polymorphisms in the Interleukin 18 Receptor 1 Gene and Tuberculosis Susceptibility among Chinese

Tuberculosis (TB), an infectious disease caused by infection of Mycobacterium tuberculosis, is a major public health challenge globally. Genetic epidemiological evidence suggests a genetic basis for TB, but the molecular mechanism for a genetic predisposition to TB remains largely unknown. Thirty-five tag single-nucleotide polymorphisms (SNPs) across 11 candidate cytokines and...

Central Angiotensin II Stimulation Promotes β Amyloid Production in Sprague Dawley Rats

Background Stress and various stress hormones, including catecholamines and glucocorticoids, have recently been implicated in the pathogenesis of Alzheimer's disease (AD), which represents the greatest unresolved medical challenge in neurology. Angiotensin receptor blockers have shown benefits in AD and prone-to-AD animals. However, the mechanisms responsible for their efficacy...