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45 papers found.
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Monitoring HIV DNA and cellular activation markers in HIV-infected humanized mice under cART

The major obstacle to cure of HIV type-1 infection is the presence of the HIV reservoir, hidden from the immune system and insensitive to combined antiretroviral therapy (cART). Eradication approaches have been hindered by the difficulty for accurately monitoring its size in vivo, especially in the lymphoid organs. Humanized mouse models are a valuable tool for systematically...

Thiazole Amides, A Novel Class of Algaecides against Freshwater Harmful Algae

Currently, harmful algal blooms are being one of ever-increasing global environmental problems. Much attention has been paid to the use of natural products as the selective algaecides due to their low toxicity, high selectivity and eco-friendly properties. In the present study, the thiazole alkaloid (1), originally isolated from Thermoactino-myces strain TM-64, was shown to...

Combination of near-infrared and thermal imaging techniques for the remote and simultaneous measurements of breathing and heart rates under sleep situation

technique is acceptable for BR and HR estimations during nighttime. Author Contributions Data curation: Duo Li, Yezhao Fan, Huiyu Duan, Wenhan Zhu. Funding acquisition: Menghan Hu, Guangtao Zhai ... . Methodology: Menghan Hu, Guangtao Zhai, Duo Li, Yezhao Fan, Xiaokang Yang. Software: Menghan Hu, Duo Li, Yezhao Fan, Huiyu Duan. Validation: Menghan Hu. Writing ± original draft: Menghan Hu, Guangtao Zhai

Design and Development Framework of Safety-Critical Software in HTR-PM

addressed to Duo Li; nc.ude.auhgnist@oudil Received 29 December 2016; Revised 19 May 2017; Accepted 28 May 2017; Published 28 June 2017 Academic Editor: Luca Podofillini Copyright © 2017 Chao Guo et al

Primary multidrug-resistant tuberculosis versus drug-sensitive tuberculosis in non-HIV-infected patients: Comparisons of CT findings

Background Multidrug-resistant tuberculosis has emerged as a global threat. The aim of this work was to compare the CT findings of primary multidrug-resistant tuberculosis and drug-sensitive tuberculosis in non-AIDS adults. Material and methods From January 2012 to February 2016, 89 patients with primary multidrug-resistant tuberculosis were retrospectively reviewed, and 89...

Regulation of proliferation and cell cycle by protein regulator of cytokinesis 1 in oral squamous cell carcinoma

Protein regulator of cytokinesis 1 (PRC1), a microtubule-associated protein, has emerged as a critical regulator of proliferation and apoptosis, acting predominantly in numerous tumors. However, its function in oral squamous cell carcinoma (OSCC) is still unknown. To establish the roles of PRC1 in OSCC, 95 oral clinical samples (54 OSCC, 24 oral leukoplakia [OLK], and 17 normal...

Association of CKD-MBD Markers with All-Cause Mortality in Prevalent Hemodialysis Patients: A Cohort Study in Beijing

The relationships between all-cause mortality and serum intact parathyroid hormone (iPTH), calcium, and phosphate are fairly diverse in patients on maintenance hemodialysis according to prior studies. This study evaluated the association of chronic kidney disease-mineral and bone disorder (CKD-MBD) markers with all-cause mortality in prevalent hemodialysis patients from 2007 to...

Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on Major Eicosanoids: A Systematic Review and Meta-Analysis from 18 Randomized Controlled Trials

Background Marine-derived n-3 polyunsaturated fatty acids (PUFA) may have a beneficial effect on inflammation via lowering pro-inflammatory eicosanoid concentrations. We aimed to assess the effect of marine-derived n-3 PUFA on prostaglandin E2 (PGE2), thromboxane B2 (TXB2), and leukotriene B4 (LTB4) through systematic review and meta-analysis of randomized controlled trials...

Association of serum fatty acid and estimated desaturase activity with hypertension in middle-aged and elderly Chinese population

ScholarSearch for Xiong-Wei Ye in:Nature Research journals • PubMed • Google ScholarSearch for Wei Yu in:Nature Research journals • PubMed • Google ScholarSearch for Duo Li in:Nature Research journals • PubMed ... and approved the final version. Competing interests The authors declare no competing financial interests. Corresponding authors Correspondence to Wei Yu or Duo Li. Supplementary information PDF

The role of semaphorin 4D as a potential biomarker for antiangiogenic therapy in colorectal cancer

The role of semaphorin 4D as a potential biomarker for antiangiogenic therapy in colorectal cancer Xiaojie Ding,1,2,* Lijuan Qiu,1,2,* Lijuan Zhang,3 Juemin Xi,1,2 Duo Li,1,2 Xinwei Huang,1,2 Yujiao

Exploratory serum fatty acid patterns associated with blood pressure in community-dwelling middle-aged and elderly Chinese

Background Epidemiological studies have assessed relationships between circulating levels of fatty acid (FA) and blood pressure (BP), and their results remain controversial. Nevertheless, data are sparse on serum FA as biomarker and BP in China. The aim of the study was to investigate the association between serum FA and BP in Chinese populations. Methods We conducted a cross...

Biospecimen Long-Chain N-3 PUFA and Risk of Colorectal Cancer: A Meta-Analysis of Data from 60,627 Individuals

Background Several prospective cohort and case-control studies reported the inconsistent association between biospecimen composition of C20 and C22 long-chain (LC) n-3 polyunsaturated fatty acid (PUFA) and colorectal cancer (CRC) risk. The aim of the present study was to investigate the association of biospecimen LC n-3 PUFA with CRC risk based on prospective cohort and case...

New utility of an old marker: serum low-density lipoprotein predicts histopathological response of neoadjuvant chemotherapy in locally advanced gastric cancer

Teng,1 Qin-Chuan Wang,1 Ji Wang,1 Qun Wei,1,3 Zi-Duo Li,1,4 Jian-Guo Shen,1 Lin-Bo Wang1,5 1Department of Surgical Oncology, Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, 2Department

Serum metabolomics profiles in response to n-3 fatty acids in Chinese patients with type 2 diabetes: a double-blind randomised controlled trial

We aimed to investigate the change of serum metabolomics in response to n-3 fatty acid supplements in Chinese patients with type 2 diabetes (T2D). In a double-blind parallel randomised controlled trial, 59 Chinese T2D patients were randomised to receive either fish oil (FO), flaxseed oil (FSO) or corn oil capsules (CO, served as a control group) and followed up for 180 days. An...

Association of homocysteine with type 2 diabetes: a meta-analysis implementing Mendelian randomization approach

Background We tested the hypothesis that elevated homocysteine (Hcy) level is causally associated with increased risk of type 2 diabetes mellitus (T2DM). Results The meta-analysis and Mendelian randomization analysis were performed among 4011 cases and 4303 controls. The absolute pooled mean Hcy concentration in subjects with MTHFR 677TT was 5.55 μmol/L (95% CI, 1.33 to 9.77...

Antibody-dependent enhancement of dengue virus infection inhibits RLR-mediated Type-I IFN-independent signalling through upregulation of cellular autophagy

Academy of Medical Sciences, and Peking Union Medical College, Kunming 650118, PR ChinaXinwei Huang, Yaofei Yue, Duo Li, Yujiao Zhao, Lijuan Qiu, Junying Chen, Yue Pan, Juemin Xi, Xiaodan Wang, Qiangming ... Sun & Qihan LiYunnan Key Laboratory of Vaccine Research & Development on Severe Infectious Diseases, Kunming 650118, PR ChinaXinwei Huang, Yaofei Yue, Duo Li, Yujiao Zhao, Lijuan Qiu, Junying Chen, Yue

Preparation and Photocatalytic Activity of Ag Modified Ti-Doped-Bi2O3 Photocatalyst

Ti doped Bi2O3 (TDB) and Ag ion modified Ti doped Bi2O3 (Ag@TDB) photocatalysts were prepared by framework replacement synthesis method with different Ag loadings (0.05, 0.3, 0.75, and 1.0 mol/L AgNO3). The structural properties of the prepared catalysts were studied by scanning electron microscope (SEM), X-ray diffraction (XRD), BET surface area, and UV/Vis diffuse reflectance...

Preparation and Photocatalytic Activity of Ag Modified Ti-Doped-Bi2O3 Photocatalyst

Ti doped Bi2O3 (TDB) and Ag ion modified Ti doped Bi2O3 (Ag@TDB) photocatalysts were prepared by framework replacement synthesis method with different Ag loadings (0.05, 0.3, 0.75, and 1.0 mol/L AgNO3). The structural properties of the prepared catalysts were studied by scanning electron microscope (SEM), X-ray diffraction (XRD), BET surface area, and UV/Vis diffuse reflectance...

Preparation and Photocatalytic Activity of Ag Modified Ti-Doped-Bi2O3 Photocatalyst

Ti doped Bi2O3 (TDB) and Ag ion modified Ti doped Bi2O3 (Ag@TDB) photocatalysts were prepared by framework replacement synthesis method with different Ag loadings (0.05, 0.3, 0.75, and 1.0 mol/L AgNO3). The structural properties of the prepared catalysts were studied by scanning electron microscope (SEM), X-ray diffraction (XRD), BET surface area, and UV/Vis diffuse reflectance...

Effect of Marine-Derived n-3 Polyunsaturated Fatty Acids on C-Reactive Protein, Interleukin 6 and Tumor Necrosis Factor α: A Meta-Analysis

Background Previous studies did not draw a consistent conclusion about the effects of marine-derived n-3 polyunsaturated fatty acids (PUFAs) on fasting blood level of C-reactive protein (CRP), interleukin 6 (IL-6) and tumor necrosis factor α (TNF-α). Methods and Findings A comprehensive search of Web of Science, PubMed, Embase and Medline (from 1950 to 2013) and bibliographies of...