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104 papers found.
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Guiding intensive care physicians’ communication and behavior towards bereaved relatives: study protocol for a cluster randomized controlled trial (COSMIC-EOL)

Kentish-Barnes, PhD, Sociologist, Famiréa Research Group, Saint Louis University Hospital, Paris Elie Azoulay, MD PhD, Famiréa Research Group, Saint Louis University Hospital, Paris Virginie Souppart

Severe toxicity from checkpoint protein inhibitors: What intensive care physicians need to know?

Checkpoint protein inhibitor antibodies (CPI), including cytotoxic T-lymphocyte-associated antigen 4 inhibitors (ipilimumab, tremelimumab) and the programmed cell death protein 1 pathway/programmed cell death protein 1 ligand inhibitors (pembrolizumab, nivolumab, durvalumab, atezolizumab), have entered routine practice for the treatment of many cancers. They improve the outcome...

Long-term health-related quality of life of critically ill patients with haematological malignancies: a prospective observational multicenter study

BackgroundAlthough outcomes of critically ill patients with haematological malignancies (HMs) have been fully investigated in terms of organ failure and mortality, data are scarce on health-related quality of life (HRQOL) in this population. We aim to assess post-intensive care unit (ICU) burden and HRQOL of critically ill patients with HMs and to identify risk factors for...

The prognostic impact of abdominal surgery in cancer patients with neutropenic enterocolitis: a systematic review and meta-analysis, on behalf the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)

Jacques Ewald 4 Olivier Turrini 4 Marion Faucher 5 Elie Azoulay 2 3 6 Djamel Mokart 5 6 0 Haematology Department, Institut Paoli Calmettes , 232 Boulevard Sainte Marguerite, 13009 Marseille Cedex 09

Focus on transfusion, bleeding and thrombosis

Conflicts of interest Elie Azoulay is a member of the board of Gilead France and over the past 3 years has received fees for lectures from Alexion, Astellas, and Gilead. Anders Perner’s ICU receives support

Impact of the condolence letter on the experience of bereaved families after a death in intensive care: study protocol for a randomized controlled trial

Background As intensive care mortality is high, end of life is a subject of major concern for intensivists. In this context, relatives are particularly vulnerable and prone to post-ICU syndrome, in the form of high levels of anxiety, depression, post-traumatic stress, and complicated grief. Grieving families suffer from a feeling of abandonment and evoke the need to get back in...

Weekly high-dose liposomal amphotericin B (L-AmB) in critically ill septic patients with multiple Candida colonization: The AmBiDex study

Background To demonstrate the feasibility and safety of weekly high-dose liposomal amphotericin B (L-AmB) (as a pre-emptive antifungal treatment) for 2 weeks in patients with septic shock and Candida colonization. Methods Pilot, multicentre, open-label, prospective study conducted in seven French ICUs. Non-immunocompromised patients, receiving mechanical ventilation were eligible...

How to treat severe infections in critically ill neutropenic patients?

Lara Zafrani 1 Elie Azoulay 0 1 0 Medical Intensive Care Unit, Hopital Saint-Louis, ECSTRA team, Biostatistics and clinical epidemiology, UMR 1153 (center of epidemiology and biostatistic Sorbonne

A Systemic Capillary Leak Syndrome (Clarkson Syndrome) in a Patient with Chronic Lymphocytic Leukemia: A Case Report in an Out-of-Hospital Setting

Recher,3 Elie Azoulay,4 and Vincent Bounes1 1Service d’Aide Médicale Urgente de la Haute Garonne (SAMU 31), Hôpital Universitaire de Purpan, place du Docteur Baylac, TSA 40031, 31059 Toulouse Cedex 9

A Systemic Capillary Leak Syndrome (Clarkson Syndrome) in a Patient with Chronic Lymphocytic Leukemia: A Case Report in an Out-of-Hospital Setting

Recher,3 Elie Azoulay,4 and Vincent Bounes1 1Service d’Aide Médicale Urgente de la Haute Garonne (SAMU 31), Hôpital Universitaire de Purpan, place du Docteur Baylac, TSA 40031, 31059 Toulouse Cedex 9

Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study

Maïté Garrouste-Orgeas Alexandre Lautrette Elie Azoulay Bruno Mourvillier Laurent Argaud Laurent Papazian Marc Gainnier Dan Goldgran-Toledano Samir Jamali Anne-Sylvie Dumenil Carole Schwebel 0 Jean ... Antimicrobials Modelling Evolution [IAME], Paris); Elie Azoulay (Medical ICU, Saint Louis Hospital, Paris); Maïté Garrouste-Orgeas (ICU, Saint-Joseph Hospital, Paris); Jean-Ralph Zahar (Infection Control Unit

Initial nutritional management during noninvasive ventilation and outcomes: a retrospective cohort study

?t? Garrouste-Orgeas Alexandre Lautrette Elie Azoulay Bruno Mourvillier Laurent Argaud Laurent Papazian Marc Gainnier Dan Goldgran-Toledano Samir Jamali Anne-Sylvie Dumenil Carole Schwebel 1 Jean-Fran ... Antimicrobials Modelling Evolution [IAME], Paris); Elie Azoulay (Medical ICU, Saint Louis Hospital, Paris); Ma?t? Garrouste-Orgeas (ICU, Saint-Joseph Hospital, Paris); Jean-Ralph Zahar (Infection Control Unit