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Mass screening for liver cancer: results from a demonstration screening project in Zhongshan City, China

in:Nature Research journals • PubMed • Google Scholar Search for Ellen T. Chang in:Nature Research journals • PubMed • Google Scholar Search for Xia Yu in:Nature Research journals • PubMed • Google Scholar

Soluble intercellular adhesion molecule-1 is associated with hepatocellular carcinoma risk: multiplex analysis of serum markers

Individualized assessment of hepatocellular carcinoma (HCC) risk in chronic liver disease remains challenging. Serum biomarkers including cytokines may offer helpful adjuncts to standard parameters for risk prediction. Our aim was to identify markers associated with increased HCC incidence. This was a prospective cohort study of 282 patients with both viral or non-viral chronic...

Association between Parkinson’s Disease and Cigarette Smoking, Rural Living, Well-Water Consumption, Farming and Pesticide Use: Systematic Review and Meta-Analysis

(JSM), Sir Colin Berry (CB), Ellen T. Chang (ETC), and Robert L. Sielken, Jr. (RLS). Dr. Charles B. Breckenridge (CBB), who is an employee of Syngenta, received annual compensation in the form of salary ... : Drs. Jack S. Mandel (JSM), Sir Colin Berry (CB), Ellen T. Chang (ETC), and Robert L. Sielken, Jr. (RLS), who are consultants to Syngenta. Ellen T. Chang and Jack S. Mandel are employed by Exponent, Inc

A critical review of the epidemiology of Agent Orange/TCDD and prostate cancer

To inform risk assessment and regulatory decision-making, the relationship between 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and prostate cancer requires clarification. This article systematically and critically reviews the epidemiologic evidence on the association between exposure to TCDD or Agent Orange, a TCDD-contaminated herbicide used during the Vietnam War, and prostate...

Cancer mortality and quantitative oil production in the Amazon region of Ecuador, 1990–2010

PurposeControversy persists over whether cancer risk is increased in communities surrounding oil fields, especially in the Oriente region of Ecuador. This ecologic study uses quantitative exposure data, updated mortality data, and improved statistical methods to study the impact of oil exploration and production activities on cancer mortality rates in the Oriente.MethodsCancer...

Dose-Response Relationship Between Serum 2,3,7,8-Tetrachlorodibenzo-p-Dioxin and Diabetes Mellitus: A Meta-Analysis

., Menlo Park, California (Ellen T. Chang, Jack S. Mandel); Division of Epidemiology, Department of Health Research and Policy, Stanford University, Palo Alto, California (Ellen T. Chang); Department of

Autoimmune and Atopic Disorders and Risk of Classical Hodgkin Lymphoma

Policy, School of Medicine, Stanford University, Stanford, California (Ellen T. Chang); Health Sciences, Exponent, Inc., Menlo Park, California (Ellen T. Chang); Department of Haematology, Rigshospitalet

Hepatitis B and liver cancer knowledge and practices among healthcare and public health professionals in China: a cross-sectional study

Background Chronic hepatitis B virus (HBV) infection is the leading cause of liver disease and liver cancer and a major source of health-related discrimination in China. To better target HBV detection and prevention programs, it is necessary to assess existing HBV knowledge, educational resources, reporting, and preventive practices, particularly among those health professionals...

Geographical and Ethnic Distribution of the HBV C/D Recombinant on the Qinghai-Tibet Plateau

Two forms of hepatitis B virus (HBV) C/D recombinant have been identified in western China, but little is known about their geographical and ethnic distributions, and particularly the clinical significance and specific mutations in the pre-core region. To address these questions, a total of 624 chronic HBV carriers from four ethnic populations representing five provinces in...

Nutrients and Genetic Variation Involved in One-Carbon Metabolism and Hodgkin Lymphoma Risk: A Population-based Case-Control Study

Nutritional and genetic determinants of the one-carbon metabolism pathway have been related to risk of malignant lymphomas, but little is known about their associations with Hodgkin lymphoma risk specifically. The authors examined nutrient intake (folate, vitamin B2, vitamin B6, vitamin B12, methionine) and multivitamin use among 497 Hodgkin lymphoma patients and 638 population...

Vitamin D Receptor Genotypes, Ultraviolet Radiation Exposure, and Risk of Non-Hodgkin Lymphoma

Ultraviolet radiation (UVR) exposure may influence risk of non-Hodgkin lymphoma (NHL) through vitamin D, with antineoplastic effects mediated through the vitamin D receptor (VDR). To explore the role of vitamin D in NHL risk and the potential interaction with UVR, the authors genotyped 10 VDR polymorphisms in 2,448 NHL patients and 1,981 controls from Denmark and Sweden who were...

San Francisco Hep B Free: A Grassroots Community Coalition to Prevent Hepatitis B and Liver Cancer

Chronic hepatitis B is the leading cause of liver cancer and the largest health disparity between Asian/Pacific Islanders (APIs) and the general US population. The Hep B Free model was launched to eliminate hepatitis B infection by increasing hepatitis B awareness, testing, vaccination, and treatment among APIs by building a broad, community-wide coalition. The San Francisco Hep...

Cigarette Smoking, Passive Smoking, and Non-Hodgkin Lymphoma Risk: Evidence From the California Teachers Study

); and Cancer Prevention Institute of California, Fremont, California (Peggy Reynolds, Ellen T. Chang, Christina A. Clarke). This work was supported by the California Breast Cancer Act of 1993; the

Recent breast cancer trends among Asian/Pacific Islander, Hispanic, and African-American women in the US: changes by tumor subtype

Background Recently, unprecedented drops in breast cancer incidence have been reported for populations of mostly White European descent. Incidence patterns in non-White racial/ethnic groups are less described. Therefore, we examined population-based breast cancer incidence trends separately for US Asian/Pacific Islander, Hispanic, African-American, and non-Hispanic White women by...

Recent trends in breast cancer incidence in US white women by county-level urban/rural and poverty status

Background Unprecedented declines in invasive breast cancer rates occurred in the United States between 2001 and 2004, particularly for estrogen receptor-positive tumors among non-Hispanic white women over 50 years. To understand the broader public health import of these reductions among previously unstudied populations, we utilized the largest available US cancer registry...

Alcohol Consumption Over Time and Risk of Lymphoid Malignancies in the California Teachers Study Cohort

, non-Hodgkin lymphoma; RR, rate ratio 1 Author affiliations: Cancer Prevention Institute of Cali- fornia (formerly the Northern California Cancer Center) , Fremont, California (Ellen T. Chang, Christina ... (Ellen T. Chang, Christina A. Clarke, Dee W. West , Pamela L. Horn-Ross); Division of Cancer Etiol- ogy, Department of Population Sciences, City of Hope Na- tional Medical Center , Duarte, California (Yani

Reproductive Factors and Non-Hodgkin Lymphoma Risk in the California Teachers Study

Background Non-Hodgkin lymphoma (NHL) is a malignancy etiologically linked to immunomodulatory exposures and disorders. Endogenous female sex hormones may modify immune function and influence NHL risk. Few studies have examined associations between reproductive factors, which can serve as surrogates for such hormonal exposures, and NHL risk by subtype. Methodology/Principal...

Reliability of Self-Reported Family History of Cancer in a Large Case–Control Study of Lymphoma

Background: Case–control studies of familial cancer risk traditionally rely on self-reported family history of cancer, which may bias results due to differential recall between case patients and control subjects. To evaluate the reliability of self-reported data, we analyzed questionnaire and registry-based data on familial cancer from a population-based case–control study of...

Parents’ Ages at Birth and Risk of Adult-onset Hematologic Malignancies Among Female Teachers in California

Bernstein, Sophia S. Wang); and Cancer Prevention Institute of California, Fremont, California (Ellen T. Chang, Christina A. Clarke, Dee W. West). This work was supported by the California Breast Cancer Act