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Intereye comparison of ocular factors in normal tension glaucoma with asymmetric visual field loss in Korean population

eye and better eye, and for asymmetric group and symmetric group, respectively. (XLSX) Author Contributions Conceptualization: Changwon Kee. Data curation: Eun Jung Lee. Formal analysis: Eun Jung ... Lee, Jong Chul Han. Investigation: Eun Jung Lee. Methodology: Eun Jung Lee, Changwon Kee. Resources: Eun Jung Lee, Jong Chul Han, Changwon Kee. Supervision: Jong Chul Han, Changwon Kee. Validation

Comparison of peripapillary vessel density between preperimetric and perimetric glaucoma evaluated by OCT-angiography

densities. (JPG) Author Contributions Conceptualization: Si Bum Kim, Changwon Kee. Data curation: Eun Jung Lee. Formal analysis: Si Bum Kim. Investigation: Si Bum Kim. Methodology: Si Bum Kim ... . Resources: Eun Jung Lee. Software: Eun Jung Lee. Supervision: Eun Jung Lee, Jong Chul Han, Changwon Kee. Validation: Eun Jung Lee, Jong Chul Han, Changwon Kee. Visualization: Changwon Kee. Writing

mTORC1 accelerates retinal development via the immunoproteasome

Yeha Kim Eun Jung Lee Cheol O. Joe Jin Woo Kim The numbers and types of cells constituting vertebrate neural tissues are determined by cellular mechanisms that couple neurogenesis to the proliferation

Composite intestinal adenoma-microcarcinoid in the colon and rectum: a case series and historical review

Composite intestinal adenoma-microcarcinoid (CIAM) is a rare colorectal lesion that mostly comprises a conventional adenomatous component with a minute proportion of neuroendocrine (NE) component. Although microcarcinoids are well-recognized in the setting of chronic inflammatory disorders of the gastrointestinal tract, large intestinal microcarcinoids associated with intestinal...

Advanced glycation end products (AGEs) promote melanogenesis through receptor for AGEs

melanogenesis through receptor for AGEs Eun Jung Lee Ji Young Kim Sang Ho Oh OPEN Accumulation of advanced glycation end products (AGEs) is linked with development or aggravation of many degenerative processes

Correlation between the Limbus-Insertion Distance of the Lateral Rectus Muscle and Lateral Rectus Recession Surgery in Intermittent Exotropia

The aim of this study was to investigate whether the limbus-insertion distance (LID) of the lateral rectus (LR) muscle can be a useful indicator for predicting the surgical effect of recession surgery in intermittent exotropia (IXT). Patients who underwent unilateral or bilateral LR recession for the basic type of IXT were included. The distance between the corneal limbus and the...

The Effect of Diurnal Fluctuation in Intraocular Pressure on the Evaluation of Risk Factors of Progression in Normal Tension Glaucoma

Purpose To investigate whether diurnal fluctuation in intraocular pressure (IOP) can influence the result of the correlations between IOP-related factors and progression of normal tension glaucoma (NTG). Methods Glaucoma progression was defined as visual field (VF) progression and changes in the optic disc and/or retinal nerve fiber layer (RNFL). Two different methods were used...

Chrysin ameliorates podocyte injury and slit diaphragm protein loss via inhibition of the PERK-eIF2α-ATF-CHOP pathway in diabetic mice

endoplasmic reticulum kinase; ROS, reactive oxygen species; UPR, unfolded protein response. Author contribution Min-Kyung KANG, Eun-Jung LEE, and Young-Hee KANG designed the research; Min-Kyung KANG, Dong ... Yeon KIM, Sin-Hye PARK, Yun-Ho KIM, and Lucia Dwi ANTIKA conducted the research; Min-Kyung KANG, Eun-Jung LEE, and Yean-Jung CHOI analyzed the data; and Min-Kyung KANG and Young-Hee KANG wrote the paper

Alteration of Inflammatory Mediators in the Upper and Lower Airways under Chronic Intermittent Hypoxia: Preliminary Animal Study

Oliveira Copyright © 2017 Eun Jung Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in

Clinical Features and Courses of Adenovirus Pneumonia in Healthy Young Adults during an Outbreak among Korean Military Personnel

Background The number of pneumonia patients increased suddenly in Korean military hospitals in late December 2014, indicating the urgent need for an epidemic outbreak investigation. Methods We conducted a prospective study of pneumonia etiology among immunocompetent young adults admitted to Daejeon Armed Forces hospital. Patient blood and sputum samples were subjected to...

The anti-inflammatory role of tissue inhibitor of metalloproteinase-2 in lipopolysaccharide-stimulated microglia

Background Tissue inhibitors of metalloproteinases (TIMPs) are known to be endogenous inhibitors of matrix metalloproteinases (MMPs). Our preliminary study showed that TIMP-2 is constitutively expressed in microglia but significantly inhibited by lipopolysaccharide (LPS) treatment. The current study was undertaken to investigate the role of TIMP-2 in microglia. Methods The...

Combination of macrophage inflammatory protein 1 alpha with existing therapies to enhance the antitumor effects on murine hepatoma

Existing therapies such as irradiation or sorafenib have limited success in the treatment of hepatocellular carcinoma (HCC) due to tumor recurrence and metastasis. Therefore, combination with other therapeutics is often considered. Macrophage inflammatory protein-1 alpha (MIP-1α) is a member of a family of chemoattractant cytokines that can induce the migration of monocytes...

β-Lapachone suppresses neuroinflammation by modulating the expression of cytokines and matrix metalloproteinases in activated microglia

Background β-Lapachone (β-LAP) is a natural naphthoquinone compound isolated from the lapacho tree (Tabebuia sp.), and it has been used for treatment of rheumatoid arthritis, infection, and cancer. In the present study, we investigated whether β-LAP has anti-inflammatory effects under in vitro and in vivo neuroinflammatory conditions. Methods The effects of β-LAP on the...

Association between Knee Osteoarthritis, Cardiovascular Risk Factors, and the Framingham Risk Score in South Koreans: A Cross-Sectional Study

Background Osteoarthritis is a significant burden on personal health and for social cost, and its prevalence is rising. Recent research has revealed an association between osteoarthritis and cardiovascular disease, and this study uses the Framingham risk score (FRS), which is widely used as a composite index of cardiovascular risk factors, to investigate the association between...

Radiation Inhibits Interleukin-12 Production via Inhibition of C-Rel through the Interleukin-6/ Signal Transducer and Activator of Transcription 3 Signaling Pathway in Dendritic Cells

Radiotherapy (RT) is a potent anti-tumor modality. However, unwanted effects including increased recurrence and metastasis that involve factors such as cytokines, which induce complex molecular mechanisms, have also been reported. In a previous study, we showed that interleukin (IL)-12 and radiotherapy combination treatment suppressed tumor growth and metastasis in a hepatoma...

IL-1 Receptor Blockade Alleviates Graft-versus-Host Disease through Downregulation of an Interleukin-1-Dependent Glycolytic Pathway in Th17 Cells

-Jung Lee,1 Eun-Kyung Kim,1 Jong Young Choi,2 and Mi-La Cho1,3 1The Rheumatism Research Center, Catholic Research Institute of Medical Sciences, The Catholic University of Korea, Seoul, Republic of Korea

A Solitary Malignant Schwannoma in the Choana and Nasal Septum

: Marco Berlucchi Copyright © 2014 Eun Jung Lee et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

Sessile serrated adenoma/polyps with a depressed surface: a rare form of sessile serrated adenoma/polyp

Sessile serrated adenoma/polyps (SSA/Ps) usually appear flat to sessile with a smooth-appearing surface. However, macroscopic appearances of SSA/P can vary from flat-elevated to nodular and can even show a pedunculated configuration as we previously reported. The aim of the current study was to evaluate the clinicopathologic features of another under-recognized form of SSA/P...

Contrasting Phylogeography of Sandy vs. Rocky Supralittoral Isopods in the Megadiverse and Geologically Dynamic Gulf of California and Adjacent Areas

Jung Lee 0 Mariana Mateos 0 Richard Cordaux, University of Poitiers, France 0 Department of Wildlife and Fisheries Sciences, Texas A&M University, College Station , Texas , United States of America

Overexpression of soluble RAGE in mesenchymal stem cells enhances their immunoregulatory potential for cellular therapy in autoimmune arthritis

Mesenchymal stem cells (MSCs) are attractive agents for cellular therapy in rheumatoid arthritis (RA). The receptor for advanced glycation end products (RAGE) serves as a pattern recognition receptor for endogenous inflammatory ligands. Soluble RAGE (sRAGE) is a truncated form of RAGE that functions as a decoy and acts as an anti-inflammatory molecule. The aim of this study was...