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Prognostic significance of CT-determined sarcopenia in patients with advanced gastric cancer

determine whether various therapies, including exercise for preventing sarcopenia, can improve the prognosis of cancer patients. Author Contributions Conceptualization: Young Saing Kim, Eun Young Kim ... . Formal analysis: Jong Soo Lee, Young Saing Kim, Eun Young Kim. Funding acquisition: Young Saing Kim. Methodology: Young Saing Kim. Resources: Young Saing Kim, Eun Young Kim. Supervision: Eun Young Kim

Trpc6 inactivation confers protection in a model of severe nephrosis in rats

Mutations in canonical transient receptor potential-6 (TRPC6) channels give rise to rare familial forms of focal and segmental glomerulosclerosis (FSGS). Here we examined a possible role for TRPC6 in the progression of chronic puromycin aminonucleoside (PAN) nephrosis in Sprague-Dawley rats, a classic model of acquired nephrotic syndromes. We used CRISPR/Cas9 technology to delete...

Pharmacokinetic comparison of a fixed-dose combination versus concomitant administration of fimasartan, amlodipine, and rosuvastatin using partial replicated design in healthy adult subjects

Oh,1 Jong-Lyul Ghim,1,2 Sung-Eun Park,2 Eun-Young Kim,1,2 Jae-Gook Shin1,2 1Department of Pharmacology and PharmacoGenomics Research Center, Inje University College of Medicine, Busan, Republic of

Monitoring of adipogenic differentiation at the single-cell level using atomic force microscopic analysis

Adipogenesis plays an important role in energy homeostasis by storing excess energy as lipid droplets. However, these reservoirs are implicated in a host of major human health problems, such as obesity. Elucidation of the mechanisms underlying adipogenesis is thus crucial to overcome these problems. The preadipocyte cell lines represent an optimal model to examine adipogenesis...

Monitoring of adipogenic differentiation at the single-cell level using atomic force microscopic analysis

Adipogenesis plays an important role in energy homeostasis by storing excess energy as lipid droplets. However, these reservoirs are implicated in a host of major human health problems, such as obesity. Elucidation of the mechanisms underlying adipogenesis is thus crucial to overcome these problems. The preadipocyte cell lines represent an optimal model to examine adipogenesis...

Social relationship changes in victim families due to a social disaster: Experiences of student victims’ families in the South Korean Sewol ferry disaster

Hee Ha 1 Eun Young Kim 1 0 Department of Psychiatry, School of Medicine, Ajou University , Kyunggi-Do , South Korea , 2 Department of Psychology, The University of Utah Asia Campus , Incheon , South ... grant, this study was funded by the South Korean government. Author Contributions Conceptualization: Sun Mi Cho, Ansuk Jeong, Jung Hee Ha, Eun Young Kim. Data curation: Sun Mi Cho, Ansuk Jeong, Jung

Educational value of pocket-sized ultrasound devices to improve understanding of ultrasound examination principles and sonographic anatomy for medical student

. Content-permission-form. S1 File. Questionnaire for students' opinions on ultrasound training. Author Contributions Conceptualization: Eun Young Kim, Kwi Hwa Park. Data curation: Eun Young Kim, Kwi Hwa ... Park. Formal analysis: Eun Young Kim, Kwi Hwa Park, Seung Joon Choi. Funding acquisition: Wook-Jin Chung. Investigation: Eun Young Kim, Seung Joon Choi. Methodology: Eun Young Kim, Kwi Hwa Park

Initial experience with laparoscopic radical antegrade modular pancreatosplenectomy for left-sided pancreatic cancer in a single institution: technical aspects and oncological outcomes

Laparoscopic surgery has been performed less frequently in the era of pancreatic cancer due to technical difficulties and concerns about oncological safety. Radical antegrade modular pancreatosplenectomy (RAMPS) is expected to be helpful to obtain a negative margin during radical lymph node dissection. We hypothesized that it would also be favorable as a laparoscopic application...

Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers

Comparative pharmacokinetics of a fixed-dose combination vs concomitant administration of telmisartan and S-amlodipine in healthy adult volunteers Minkyung Oh,1,2,* Sung-Eun Park,3,* Jong-Lyul Ghim,1–3 Young-Kyung Choi,1 Eon-Jeong Shim,1–3 Jae-Gook Shin,1–3 Eun-Young Kim1–3 1Department of Pharmacology, 2PharmacoGenomics Research Center, Inje University College of Medicine, Busan...

Reference Values of Skeletal Muscle Mass for Korean Children and Adolescents Using Data from the Korean National Health and Nutrition Examination Survey 2009-2011

Background Skeletal muscle mass (SMM) plays a crucial role in systemic glucose metabolism. Objective To obtain reference data on absolute and relative values of SMM for Korean children and adolescents. Methods Cross-sectional results from 1919 children and adolescents (1024 boys) aged 10–18 years that underwent dual-energy X-ray absorptiometry (DXA) during the Korean National...

Health-Related Quality of Life in Korean Adults with Hearing Impairment: The Korea National Health and Nutrition Examination Survey 2010 to 2012

Background As the global population ages, disabling hearing impairment (HI) have been increased rapidly. The impact of HI on health-related quality of life (HRQoL) is of great importance to aid the development of strategic plans and to guide therapeutic interventions. Purpose To evaluate HRQoL in Korean adults with different degrees of HI using EuroQol five-dimensional (EQ-5D...

Pediatric fluoroquinolone prescription in South Korea before and after a regulatory intervention: A nationwide study, 2007-2015

Objective To investigate the impact of national implementation of age restriction on fluoroquinolone prescription in children and adolescents. Methods Data collected from the database of Health Insurance Review and Assessment Service in South Korea, a national health insurance system to analyze fluoroquinolone prescribing practice in children and adolescents younger than 18 years...

The role of Rad51 in safeguarding mitochondrial activity during the meiotic cell cycle in mammalian oocytes

Rad51 is a conserved eukaryotic protein that mediates the homologous recombination repair of DNA double-strand breaks that occur during mitosis and meiosis. In addition, Rad51 promotes mitochondrial DNA synthesis when replication stress is increased. Rad51 also regulates cell cycle progression by preserving the G2/M transition in embryonic stem cells. In this study, we report a...

High power laser-driven ceramic phosphor plate for outstanding efficient white light conversion in application of automotive lighting

We report on Y3Al5O12: Ce3+ ceramic phosphor plate (CPP) using nano phosphor for high power laser diode (LD) application for white light in automotive lighting. The prepared CPP shows improved luminous properties as a function of Ce3+ concentration. The luminous properties of the Y3Al5O12: Ce3+ CPP nano phosphor are improved when compared to the Y3Al5O12: Ce3+ CPP with bulk...

Prognostic Significance of Modified Advanced Lung Cancer Inflammation Index (ALI) in Patients with Small Cell Lung Cancer_ Comparison with Original ALI

Background Advanced lung cancer inflammation index (ALI, body mass index [BMI] x serum albumin/neutrophil-lymphocyte ratio [NLR]) has been shown to predict overall survival (OS) in small cell lung cancer (SCLC). CT enables skeletal muscle to be quantified, whereas BMI cannot accurately reflect body composition. The purpose was to evaluate prognostic value of modified ALI (mALI...

The Development of Infants’ Sensitivity to Behavioral Intentions when Inferring Others’ Social Preferences

The present study investigated whether infants reason about others’ social preferences based on the intentions of others’ interactive actions. In Experiment 1, 12-month-old infants were familiarized with an event in which an agent either successfully helped a circle to climb up a hill (successful-helping condition) or failed to help the circle to achieve its goal (failed-helping...

Effects of the Boron-Doped p

of Korea Received 26 July 2013; Accepted 13 September 2013 Academic Editor: Seung Hwan Ko Copyright © 2013 Eun-Young Kim and Jeong Kim. This is an open access article distributed under the

Effects of the Boron-Doped p

of Korea Received 26 July 2013; Accepted 13 September 2013 Academic Editor: Seung Hwan Ko Copyright © 2013 Eun-Young Kim and Jeong Kim. This is an open access article distributed under the

A national survey of lung cancer specialists’ views on low-dose CT screening for lung cancer in Korea

Kim, Seung Joon Kim, Jung Soo Kim, SeMin Chong, Young Sik Park, Sang-Yun Song, Jin Han Lee, Hee Kyung Ahn, Eun Young Kim, Sei Hoon Yang and Jeong Seon Ryu are members of Public Relations Committee ... , Korean Association for Lung Cancer. A lead author is Jeong Seon Ryu (). Author Contributions Conceptualization: Dong Wook Shin, Jin Han Lee, Eun Young Kim, Tae Won Jang, Moon June Cho. Data curation