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Intermittent versus continuous energy restriction on weight loss and cardiometabolic outcomes: a systematic review and meta-analysis of randomized controlled trials

This systematic review and meta-analysis summarized the most recent evidence on the efficacy of intermittent energy restriction (IER) versus continuous energy restriction on weight-loss, body composition, blood pressure and other cardiometabolic risk factors. Randomized controlled trials were systematically searched from MEDLINE, Cochrane Library, TRIP databases, EMBASE and...

Micronutrient content in enteral nutrition formulas: comparison with the dietary reference values for healthy populations

Santarpia Anna D'Isanto Franco Contaldo Fabrizio Pasanisi 0 Equal contributors Internal Medicine and Clinical Nutrition Unit - Department of Clinical Medicine and Surgery, “Federico II” University Medical

The relationship between emotional regulation and eating behaviour: a multidimensional analysis of obesity psychopathology

, Raimondo Costabile, Giuseppe Loiarro, Giuseppe Pecoraro, Fabrizio Pasanisi, GianLuca Rossetti, Diana Galletta, declare that no funding source are involved in this study. Conflict of interest On behalf of

Butyrylcholinesterase as a prognostic marker: a review of the literature

Lidia Santarpia Ilenia Grandone Franco Contaldo Fabrizio Pasanisi Background Butyrylcholinesterase (BChE) is an -glycoprotein synthesized in the liver. Its serum level decreases in many clinical

Circulating Levels of Sirtuin 4, a Potential Marker of Oxidative Metabolism, Related to Coronary Artery Disease in Obese Patients Suffering from NAFLD, with Normal or Slightly Increased Liver Enzymes

Giovanni Tarantino,1,2 Carmine Finelli,3 Franco Scopacasa,4 Fabrizio Pasanisi,1 Franco Contaldo,1 Domenico Capone,5 and Silvia Savastano1 1Department of Clinical Medicine and Surgery, Federico II University ... . Carmine Finelli collected the data. Fabrizio Pasanisi, Franco Contaldo, and Domenico Capone critically revised the text. Franco Scopacasa performed laboratory analyses. Acknowledgments Guarantor of the

Nutritional screening and early treatment of malnutrition in cancer patients

Lidia Santarpia Franco Contaldo Fabrizio Pasanisi Background Malnutrition is a frequent complication in patients with cancer and can negatively affect the outcome of treatments. On the other hand

Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy

Brown adipose tissue, where Uncoupling Protein 1 (UCP1) activity uncouples mitochondrial respiration, is an important site of facultative energy expenditure. This tissue may normally function to prevent obesity. Our aim was to investigate by sequence analysis the presence of UCP1 gene variations that may be associated with obesity. We studied 100 severe obese adults (BMI > 40 kg...

Sequence Analysis of the UCP1 Gene in a Severe Obese Population from Southern Italy

Brown adipose tissue, where Uncoupling Protein 1 (UCP1) activity uncouples mitochondrial respiration, is an important site of facultative energy expenditure. This tissue may normally function to prevent obesity. Our aim was to investigate by sequence analysis the presence of UCP1 gene variations that may be associated with obesity. We studied 100 severe obese adults (BMI > 40 kg...

Ureteroiliac Artery Fistula in a Young Woman with Short Bowel Syndrome for Radiation Enteritis

Ureteral-iliac artery fistula is a rare and potentially life-threatening complication, typically occurring after radiation therapy in already surgically treated cancer patients. This case report describes the diagnostic challenges and the successful management, with the positioning of an intra-arterial prosthesis, of a fistula between the internal iliac artery and the left ureter...

Are hepatic steatosis and carotid intima media thickness associated in obese patients with normal or slightly elevated gamma-glutamyl-transferase?

Background Hepatic steatosis (HS) has been associated with obesity and metabolic syndrome (MS), conditions carrying a high risk of coronary artery disease. We aimed to determine whether HS was an independent factor of atherogenic risk beyond its association with MS and its components. Methods We assessed the circulating levels of the heat shock protein-70 (HSP-70), a chaperone...

Young adult obese subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively?

Background Obesity is a leading risk factor for metabolic syndrome whose further expression is non-alcoholic fatty liver disease. Metabolic syndrome is associated with a proinflammatory state that contributes to insulin resistance. Finally, a "metabolically benign obesity" that is not accompanied by insulin resistance has recently been postulated to exist. Aim To find whether any...

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

Background Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis/inflammation and fibrosis. The "benignity" of fatty liver is widely accepted but conceptually difficult to maintain because the...

Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?

Inside the spectrum of non-alcoholic fatty liver disease, simple fatty liver is generally thought of as being "non progressive", differently from non-alcoholic steatohepatitis, which increases in severity due to the presence of apoptosis/inflammation and fibrosis. The "benignity