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Augmented Weighted Estimators Dealing with Practical Positivity Violation to Causal inferences in a Random Coefficient Model

The inverse probability of treatment weighted (IPTW) estimator can be used to make causal inferences under two assumptions: (1) no unobserved confounders (ignorability) and (2) positive probability of treatment and of control at every level of the confounders (positivity), but is vulnerable to bias if by chance, the proportion of the sample assigned to treatment, or proportion of...

Targeting GPER1 to suppress autophagy as a male-specific therapeutic strategy for iron-induced striatal injury

The functional outcome of intracerebral hemorrhage (ICH) in young male patients are poor than in premenopausal women. After ICH, ferrous iron accumulation causes a higher level of oxidative injury associated with autophagic cell death in striatum of male mice than in females. In rodent model of ferrous citrate (FC)-infusion that simulates iron accumulation after ICH, female...

Expression of Demethylase Genes, FTO and ALKBH1, Is Associated with Prognosis of Gastric Cancer

BackgroundReversible N6-methyladenosine (m6A) modifications in messenger RNAs can be categorized under the field of “RNA epigenetics.” However, the potential role of m6A-related genes in gastric cancer (GC) prognosis has not been systematically researched.AimsThis study was aimed at providing insights into the prognostic role of m6A-related gene expression, at both mRNA and...

Heat stress induces proteomic changes in the liver and mammary tissue of dairy cows independent of feed intake: An iTRAQ study

, Ireland) for careful reading of the manuscript. Author Contributions Conceptualization: Lu Ma, Yongxin Yang. Data curation: Lu Ma, Yongxin Yang. Formal analysis: Lu Ma, Yongxin Yang, Fang Wang

Application of the Modified Inverse Design Method in the Optimization of the Runner Blade of a Mixed-Flow Pump

his bachelor degree from Northwestern Polytechnical University, China, in 2013. His research interests include pump design and inner flow analysis of the unshroud centrifugal impeller Xiao-Fang Wang

Polymeric Organo-Silane Coatings for Aluminum Alloy Corrosion Protection by Self-Assembled Metho

The protective performances of coating formed by organo-silane with a linear alkyl chain for promoting aluminum alloy corrosion protection were evaluated by electrochemical techniques. The coatings were self-assembled in the hydrolyzed hydroalcoholic bath of n-octyltriethoxysilane (OS) and cured at hot air oven by different time. The coatings prepared by the less self-assembled...

Polymeric Organo-Silane Coatings for Aluminum Alloy Corrosion Protection by Self-Assembled Metho

The protective performances of coating formed by organo-silane with a linear alkyl chain for promoting aluminum alloy corrosion protection were evaluated by electrochemical techniques. The coatings were self-assembled in the hydrolyzed hydroalcoholic bath of n-octyltriethoxysilane (OS) and cured at hot air oven by different time. The coatings prepared by the less self-assembled...

Translating cancer genomics into precision medicine with artificial intelligence: applications, challenges and future perspectives

In the field of cancer genomics, the broad availability of genetic information offered by next-generation sequencing technologies and rapid growth in biomedical publication has led to the advent of the big-data era. Integration of artificial intelligence (AI) approaches such as machine learning, deep learning, and natural language processing (NLP) to tackle the challenges of...

Cognitive function and 3-year mortality in the very elderly Chinese population with chronic kidney disease

Cognitive function and 3-year mortality in the very elderly Chinese population with chronic kidney disease Kunhao Bai,1,2 Yujing Pan,3 Fanghong Lu,4 Yingxin Zhao,4 Fang Wang,1,5 Luxia Zhang1,5,6

A DFA-based bivariate regression model for estimating the dependence of PM2.5 among neighbouring cities

On the basis of detrended fluctuation analysis (DFA), we propose a new bivariate linear regression model. This new model provides estimators of multi-scale regression coefficients to measure the dependence between variables and corresponding variables of interest with multi-scales. Numerical tests are performed to illustrate that the proposed DFA-bsaed regression estimators are...

Patients’ sense of responsibility to healthcare providers and its predictors: A national cross-sectional survey in China

Jiang, Hua Qin, Aiguo Liu, Xi Zhu, Naixing Zhang, Yuan Liang. Data curation: Beizhu Ye, Xinzi Wang, Fang Wang, Ping Zhang, Yao Cheng, Yi Sun, Hongwei Jiang, Yang Liu. Formal analysis: Beizhu Ye, Fang ... Wang, Ping Zhang, Yao Cheng, Yi Sun, Aiguo Liu, Yang Liu, Xi Zhu, Yuan Liang. Funding acquisition: Yuan Liang. Investigation: Beizhu Ye, Xinzi Wang, Fang Wang, Ping Zhang, Yao Cheng, Yi Sun, Aiguo

Adaptive tracking control for a class of uncertain nonlinear systems with infinite number of actuator failures using neural networks

We consider adaptive compensation for infinite number of actuator failures in the tracking control of uncertain nonlinear systems. We construct an adaptive controller by combining the common Lyapunov function approach and the structural characteristic of neural networks. The proposed control strategy is feasible under the presupposition that the systems have a nonstrict-feedback...

Adaptive tracking control for a class of uncertain nonlinear systems with infinite number of actuator failures using neural networks

We consider adaptive compensation for infinite number of actuator failures in the tracking control of uncertain nonlinear systems. We construct an adaptive controller by combining the common Lyapunov function approach and the structural characteristic of neural networks. The proposed control strategy is feasible under the presupposition that the systems have a nonstrict-feedback...

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9)

MicroRNA-425 promotes the development of lung adenocarcinoma via targeting A disintegrin and metalloproteinases 9 (ADAM9) Ruibao Liu, Fang Wang, Yanchun Guo, Jianmei Yang, Shaoping Chen, Xin Gao

Quantitative Determination of Chlormequat Chloride Residue in Wheat Using Surface-Enhanced Raman Spectroscopy

A simple and sensitive method for detection of chlormequat chloride residue in wheat was developed using surface-enhanced Raman spectroscopy (SERS) coupled with chemometric methods on a portable Raman spectrometer. Pretreatment of wheat samples was performed using a two-step extraction procedure. Effective and uniform active substrate (gold nanorods) was prepared and mixed with...

Quantitative Determination of Chlormequat Chloride Residue in Wheat Using Surface-Enhanced Raman Spectroscopy

A simple and sensitive method for detection of chlormequat chloride residue in wheat was developed using surface-enhanced Raman spectroscopy (SERS) coupled with chemometric methods on a portable Raman spectrometer. Pretreatment of wheat samples was performed using a two-step extraction procedure. Effective and uniform active substrate (gold nanorods) was prepared and mixed with...

The key elements and effects of the integration between private secondary hospital and public township health center in China

Introduction: It is a challenging issue in China that how to change the segmentation and build an integrated health systems in the new health care reform initiated in 2009. Constructing the collaboration among primary, the secondary and tertiary health institutions is regarded as one of the most feasible ways which has been encouraged and tried in practice. Therefore, it is vital...

Cyclooxygenase-2 up-regulates hepatic somatostatin receptor 2 expression

Wang conceived and designed the experiments; Yao-Yao Lu, Jin-Hang Gao, Chong Zhao and Shi-Lei Wen were involved in the cell-based and molecular biology experiments; Yu-Fang Wang analyzed the data; and ... Yao-Yao Lu, Jin-Hang Gao and Cheng-Wei Tang wrote the paper. Yu-Fang Wang, Jin-Hang Gao and Cheng-Wei Tang obtained funding. Competing Interests: The authors declare no competing interests

Factors affecting the pilot trading market of carbon emissions in China

Climate change and carbon emissions are major problems which are attracting worldwide attention. China has had its pilot carbon emission trading markets in seven regions for more than 3 years. What affects carbon emission trading market in China is a big question. More attention is paid to how China promotes the carbon emission trading schemes in the whole country. This paper...

Precursory strong-signal characteristics of the convective clouds of the Central Tibetan Plateau detected by radar echoes with respect to the evolutionary processes of an eastward-moving heavy rainstorm belt in the Yangtze River Basin

The integrated analysis of the data from a C-band frequency-modulated continuous-wave (C-FMCW) radar site in Naqu obtained during a rainstorm over the middle and lower reaches of the Yangtze River and the data concerning the three-dimensional structure of the circulation of the precipitation system that occurred over the lower reaches of the Yangtze River Basin during the Third...