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The mutation rates of EGFR in non-small cell lung cancer and KRAS in colorectal cancer of Chinese patients as detected by pyrosequencing using a novel dispensation order

Background The purpose of this study was to develop a cost-effective approach for the determination of EGFR and KRAS mutations in formalin-fixed paraffin-embedded (FFPE) non-small cell lung cancer (NSCLC) and colorectal cancer (CRC) samples from Chinese patients based on a sensitive pyrosequencing (PS) technique. Methods The NSCLC and CRC cell lines were tested to determine the...

The mutation rates of EGFR in non-small cell lung cancer and KRAS in colorectal cancer of Chinese patients as detected by pyrosequencing using a novel dispensation order

dispensation order Guohua Xie†1, Fang Xie†1, Ping Wu2, Xiangliang Yuan1, Yanhui Ma1, Yunchuan Xu1, Li Li1, Ling Xu1, Ming Yang3Email author and Lisong Shen1Email author †Contributed equally Journal of ... patients at the clinical laboratory level. Notes Guohua Xie and Fang Xie contributed equally to this work. Declarations Acknowledgments This study was supported by grants from the National Natural