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Different levels of hypoglycemia in patients with type 2 diabetes, their achieved mean HbA1c vs. all-cause and cardiovascular mortality

complications collected in this study. (DOCX) Author Contributions Conceptualization: Seng-Wei Ooi, Hua-Fen Chen. Data curation: Seng-Wei Ooi. Formal analysis: Ya-Hui Chang, Hua-Fen Chen. Writing – original ... draft: Seng-Wei Ooi, Shu-Tin Yeh, Hua-Fen Chen. Writing – review & editing: Shu-Tin Yeh, Chung-Yi Li, Hua-Fen Chen. 10 / 12 diabetes: Prospective analysis of the Joint Asia Diabetes Evaluation Registry

Low mean HbA1c does not increase all-cause and cardiovascular mortality in patients with diabetes: Effect-modifications by anemia and chronic kidney disease stages

Legislation. Funding: This study was supported to Seng-Wei Ooi and Hua-Fen Chen by grants from the Far Eastern Memorial Hospital (FEMH-2021-C-043 and FEMH-2021-C-034, respectively). The funders had no role in ... with all covariates included in Model 2 plus comorbidities, complications, and laboratory result. (DOCX) Author Contributions Conceptualization: Seng-Wei Ooi, Shu-Tin Yeh, Chung-Yi Li, Hua-Fen Chen

Impact of Logistics Development on Economic Growth: An Empirical Research from Guangdong Province in China

Copyright © 2021 Xiaofei Li and Fen Chen. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any

Spatial Spillover Effect of Government Public Health Spending on Regional Economic Growth during the COVID-19 Pandemic: An Evidence from China

: An Evidence from China Xiaofei Li,1,2 Fen Chen,3 and Songbo Hu4 1Zhuhai Da Hengqin Science and Technology Development Co., Ltd., Zhuhai 519031, China 2Hengqin Finance Research Institute of Jilin

Policies and Transformation of Long-Term Care System in Taiwan

The Taiwanese government has been facing severe challenges pressed by population ageing. The government started taking the issue of long-term care seriously since the first rotation of the political parties in 2000. However, early plans for long-term care were limited in terms of coverage. The Long-Term Care 2.0 Plan—a tax-funded, universal plan—was implemented in 2016. Soon...

Estimated glomerular filtration rate and arterial stiffness in Japanese population: a secondary analysis based on a cross-sectional study

Evidence regarding the relationship between estimated glomerular filtration rate (eGFR) and arterial stiffness is limited, and the data analysis is not sufficient to clarify the true relationship between the two. We aimed to investigate the relationship between eGFR and brachial-ankle pulse wave velocity (baPWV) in Japanese. The present study was a cross-sectional study. Nine...

Mixture toxicity of zinc oxide nanoparticle and chemicals with different mode of action upon Vibrio fischeri

Zinc oxide nanoparticle (nZnO) and chemicals with different mode of action (MOA, i.e., narcotic and reactive) were frequently detected in the Yangtze River. Organisms are typically exposed to mixtures of nZnO and other chemicals rather than individual nZnO. Toxicity of nZnO is caused by the dissolution of Zn2+, which has been proved in the field of single toxicity. However, it is...

The mixture toxicity of heavy metals on Photobacterium phosphoreum and its modeling by ion characteristics-based QSAR

Conceptualization: Mi Li, Xiaoming Zou. Data curation: Fen Chen, Ligui Wu, Huan Zhang. 10 / 13 Methodology: Xiaoming Zou. Supervision: Xiaoming Zou. Writing – original draft: Jianjun Zeng, Ligui Wu. Writing

Shape Modeling Based on Convolutional Restricted Boltzmann Machines

This paper proposes a kind of shape model based on convolutional restricted Boltzmann machines(CRBM), which can be used to assist the task of image target detection and classification. The CRBM is a generative model that can model shapes through the generative capabilities of the model. This paper presents the visual representation, construction process and training method of the...

Multi-strain probiotic supplement attenuates streptozotocin-induced type-2 diabetes by reducing inflammation and β-cell death in rats

Lin, Jui-Fen Chen. Writing – review & editing: Pei-Shan Hsieh, Hsieh-Hsun Ho, Shih-Hung Hsieh, Wen-Yang Lin, Jui-Fen Chen. 13 / 16 14 / 16 24. Phillips MS, Liu Q, Hammond HA, Dugan V, Hey PJ, Caskey

Clinical and microstructural changes with different iontophoresis-assisted corneal cross-linking methods for keratoconus

AIM: To compare the clinical and microstructural changes induced by different transepithelial iontophoresis-assisted corneal cross-linking (I-CXL) methods for keratoconus. METHODS: A total of 42 eyes of 42 patients with progressive keratoconus were divided into two groups. Group A received I-CXL for 5min, while group B received I-CXL for 10min. Visual acuity, optical coherence...

The Response of Prostate Cancer to Androgen Deprivation and Irradiation Due to Immune Modulation

This study investigated changes in the immune system and the biological consequences of androgen deprivation therapy (ADT) and radiotherapy (RT) for augmenting the treatment response in prostate cancer, particularly for castration-resistant prostate cancer (CRPC). Human and murine prostate cancer cell lines were used to examine the response to ADT and RT in vitro and in vivo...

Incidence of idiopathic cardiomyopathy in patients with type 2 diabetes in Taiwan: age, sex, and urbanization status-stratified analysis

Chen School of Medicine and Department of Public Health, College of Medicine, Fujen Catholic University, New Taipei City, Taiwan Hua-Fen Chen Department of Public Health, College of Medicine, National ... of Healthcare Administration, College of Medical and Health Science, Asia University, Taichung City, Taiwan Chung-Yi Li AuthorsHua-Fen Chen View author publications You can also search for this

Effect of Tumor Burden on Tumor Aggressiveness and Immune Modulation in Prostate Cancer: Association with IL-6 Signaling

Local treatment is known to improve survival in men with locally advanced prostate cancer (LAPC), but the underlying mechanisms remain unclear. In the present study, we examined the role of tumor burden in tumor aggressiveness, as well as the pathway responsible for these changes. We used human and murine prostate cancer cell lines to examine the role of tumor burden in tumor...

Association between lipoproteins and telomere length in US adults: data from the NHANES 1999–2002

Evidence regarding the correlation between lipoproteins and telomere length in US adults is limited. We aimed to investigate whether lipoproteins was associated with telomere length using US National Health and Nutrition Examination Survey (NHANES) database. A total of 6468 selected participants were identified in the NHANES Data Base (1999–2002). The independent and dependent...

Performance Comparison of the Deep Learning and the Human Endoscopist for Bleeding Peptic Ulcer Disease

Management of peptic ulcer bleeding is clinically challenging. Accurate characterization of the bleeding during endoscopy is key for endoscopic therapy. This study aimed to assess whether a deep learning model can aid in the classification of bleeding peptic ulcer disease. Endoscopic still images of patients (n = 1694) with peptic ulcer bleeding for the last 5 years were...

Ginsenoside Rg3 Prolongs Survival of the Orthotopic Hepatocellular Carcinoma Model by Inducing Apoptosis and Inhibiting Angiogenesis

Chen 3 Xudong Miao 3 Maryou Lambros 0 Department of Obstetrics, The Second Affiliated Hospital of Zhejiang University School of Medicine , Hangzhou 310000 , China 1 Department of Respiratory Hangzhou

Switching from glargine+insulin aspart to glargine+insulin aspart 30 before breakfast combined with exercise after dinner and dividing meals for the treatment of type 2 diabetes patients with poor glucose control – a prospective cohort study

This study aimed to examine the switch from glargine+once daily insulin aspart (1 + 1 regimen) to glargine+insulin aspart 30 before breakfast combined with exercise and in patients with type 2 diabetes mellitus (T2DM) with poorly controlled blood glucose levels. Consecutive patients with poorly controlled T2DM (n = 182) were switched from the 1 + 1 regimen to glargine+insulin...

No-reference quality metric for high dynamic range imaging system based on curvature analysis in tensor domain

ZONGJU PENG 0 FEN CHEN 0 0 Faculty of Information Science and Engineering, Ningbo University , Ningbo , China 1 National Key Lab of Software New Technology, Nanjing University , Nanjing , China High

The Transcription Factor Sfp1 Regulates the Oxidative Stress Response in Candida albicans

Candida albicans is a commensal that inhabits the skin and mucous membranes of humans. Because of the increasing immunocompromised population and the limited classes of antifungal drugs available, C. albicans has emerged as an important opportunistic pathogen with high mortality rates. During infection and therapy, C. albicans frequently encounters immune cells and antifungal...