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Short-term apparent brain tissue changes are contributed by cerebral blood flow alterations

Qianjiang Endowed Professor Program, National Natural Science Foundation of China (No. 61671198). Author Contributions Conceptualization: Thomas Liu, Yu-Feng Zang, Ze Wang. Data curation: Qiu Ge, Wei Peng ... Peng, Jian Zhang, Ze Wang. Writing ± original draft: Qiu Ge, Ze Wang. Writing ± review & editing: Qiu Ge, Wei Peng, Jian Zhang, Xuchu Weng, Yong Zhang, Thomas Liu, Yu-Feng Zang, Ze Wang. 9 / 12 14. 10

Reproducibility of frequency-dependent low frequency fluctuations in reaction time over time and across tasks

-CV values across the three conditions. (DOCX) Acknowledgments We thank Jin-Xuan Cheng for her help with recruiting subjects. Dr. Yu-Feng Zang is partly supported through the ªQian Jiang Distinguished ... : Zan-Zan Liu, Meng-Jian Han, Hang Zhang. Funding acquisition: Lie-Zhong Ge, Yu-Feng Zang, Hang Zhang. Investigation: Zan-Zan Liu. Methodology: Zan-Zan Liu, Hui-Jie Qu, Zhuo-Ling Tian. Project

Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis

conflict of interests. Authors’ Contributions Rongbin Yu and Peng Huang participated in the design of the study. Yinan Yao, Ming Yue, Mei Liu, and Feng Zang took charge of data collection and quality control

Grazoprevir and Elbasvir in Patients with Genotype 1 Hepatitis C Virus Infection: A Comprehensive Efficacy and Safety Analysis

conflict of interests. Authors’ Contributions Rongbin Yu and Peng Huang participated in the design of the study. Yinan Yao, Ming Yue, Mei Liu, and Feng Zang took charge of data collection and quality control

Characterizing the Blood Oxygen Level-Dependent Fluctuations in Musculoskeletal Tumours Using Functional Magnetic Resonance Imaging

This study characterized the blood oxygen level-dependent (BOLD) fluctuations in benign and malignant musculoskeletal tumours via power spectrum analyses in pre-established low-frequency bands. BOLD MRI and T1-weighted imaging (T1WI) were collected for 52 patients with musculoskeletal tumours. Three ROIs were drawn on the T1WI image in the tumours’ central regions, peripheral...

White Matter Microstructural Alterations in Children with ADHD: Categorical and Dimensional Perspectives

Studies of brain alterations in children with attention-deficit/hyperactivity disorder (ADHD) have shown heterogeneous results. The aims of the current study were to investigate white matter microstructure in children using both categorical and dimensional definitions of ADHD and to determine the functional consequences of observed alterations. In a large single-site sample of...

Low-Frequency Fluctuations of the Resting Brain: High Magnitude Does Not Equal High Reliability

. Competing Interests: Prof. Yu-Feng Zang is a PLOS ONE Editorial Board member. However, this does not alter the authors' adherence to PLOS ONE Editorial policies and criteria. of the commonly used and easiest

Individual Variability and Test-Retest Reliability Revealed by Ten Repeated Resting-State Brain Scans over One Month

Individual differences in mind and behavior are believed to reflect the functional variability of the human brain. Due to the lack of a large-scale longitudinal dataset, the full landscape of variability within and between individual functional connectomes is largely unknown. We collected 300 resting-state functional magnetic resonance imaging (rfMRI) datasets from 30 healthy...

Local Activity and Causal Connectivity in Children with Benign Epilepsy with Centrotemporal Spikes

The aim of the current study was to localize the epileptic focus and characterize its causal relation with other brain regions, to understand the cognitive deficits in children with benign childhood epilepsy with centrotemporal spikes (BECTS). Resting-state functional magnetic resonance imaging (fMRI) was performed in 37 children with BECTS and 25 children matched for age, sex...

Functional Connectome before and following Temporal Lobectomy in Mesial Temporal Lobe Epilepsy

. Richardson Yu-Feng Zang Zhiqiang Zhang Guangming Lu As mesial temporal lobe epilepsy (mTLE) has been recognized as a network disorder, a longitudinal connectome investigation may shed new light on the

Effects of Finger Tapping Frequency on Regional Homogeneity of Sensorimotor Cortex

Zang 0 Nanyin Zhang, University of Massachusetts Medical School, United States of America 0 1 Max Planck Institute for Human Cognitive and Brain Sciences , Leipzig, Germany , 2 Center for Cognition and

Detecting Static and Dynamic Differences between Eyes-Closed and Eyes-Open Resting States Using ASL and BOLD fMRI

Resting-state fMRI studies have increasingly focused on multi-contrast techniques, such as BOLD and ASL imaging. However, these techniques may reveal different aspects of brain activity (e.g., static vs. dynamic), and little is known about the similarity or disparity of these techniques in detecting resting-state brain activity. It is therefore important to assess the static and...

Disrupted Causal Connectivity in Mesial Temporal Lobe Epilepsy

preparation of the manuscript. Competing Interests: Yu-Feng Zang serves as an editor and he is one of the co-authors. This does not alter the authors adherence to all the PLOS ONE policies on sharing data and ... , providing valuable information to understand the pathophysiology of this disorder. - Funding: This research was supported by grants from the Natural Science Foundation of China (81020109022/H1802 to Yu-Feng

5-HTTLPR Polymorphism Impacts Task-Evoked and Resting-State Activities of the Amygdala in Han Chinese

Background Prior research has shown that the amygdala of carriers of the short allele (s) of the serotonin transporter (5-HTT) gene (5-HTTLPR) have a larger response to negative emotional stimuli and higher spontaneous activity during the resting state than non-carriers. However, recent studies have suggested that the effects of 5-HTTLPR may be specific to different ethnic groups...

Functional and Anatomical Connectivity Abnormalities in Cognitive Division of Anterior Cingulate Cortex in Schizophrenia

Introduction Current pathophysiological theories of schizophrenia highlight the role of altered brain functional and anatomical connectivity. The cognitive division of anterior cingulate cortex (ACC-cd) is a commonly reported abnormal brain region in schizophrenia for its importance in cognitive control process. The aim of this study was to investigate the functional and...

The Effects of Prenatal Alcohol Exposure on the Developmental Retina of Mice

Aims: Our aim is to investigate the effects of prenatal alcohol exposure (PAE) on the development of retinal bipolar and horizontal cells. Methods: The alterations of the retinal bipolar and horizontal cells in P7, P14 and P30 mice were observed after PAE, with immunofluorescent labeling and DiI diolistic assay. Results: The retinal development of filial pups was affected by PAE...

Effects of Apolipoprotein E Genotype on the Off-Line Memory Consolidation

study design, data collection and analysis, decision to publish, or preparation of the manuscript. Competing Interests: The authors Yu-Feng Zang, Yong He, and Xi-Nian Zuo of this manuscript serve as

REST: A Toolkit for Resting-State Functional Magnetic Resonance Imaging Data Processing

Resting-state fMRI (RS-fMRI) has been drawing more and more attention in recent years. However, a publicly available, systematically integrated and easy-to-use tool for RS-fMRI data processing is still lacking. We developed a toolkit for the analysis of RS-fMRI data, namely the RESting-state fMRI data analysis Toolkit (REST). REST was developed in MATLAB with graphical user...

An open science resource for establishing reliability and reproducibility in functional connectomics

-Feng Zang, Qinglin Zhang, Zhiqiang Zhang, Ke Zhao, Zonglei Zhen, Yuan Zhou, Xi-Nian Zuo. Additional information Tables 2?6 are only available in the online version of this paper. Supplementary