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A Comprehensive Review on Copemyl®

expertise on a regulatory matter. Francesco Patti served on scientific advisory boards for Almirall, Bayer, Biogen, Celgene, Merck, Novartis, Roche, Sanofi, and TEVA; he served on speakers’ bureau for

Correction to: Management of pregnancy-related issues in multiple sclerosis patients: the need for an interdisciplinary approach

The original version contained a mistake. The authors have specified only in a few paragraphs that all the contents of the paper are meant for Copaxone but not for unbranded glatiramer acetate, Authors ask to add the specification of Copaxone or branded glatiramer acetate everytime.

Clinical and radiologic rebound after discontinuation of natalizumab therapy in a highly active multiple sclerosis patient was not halted by dimethyl-fumarate: a case report

report Francesco Patti 0 Carmela Leone 0 Mario Zappia 0 0 Department of Medical Sciences , Surgicals and Advanced Technologies G.F. Ingrassia , Section of Neuroscience, University of Catania , Via Santa ... ’ contributions Carmela Leone drafted the background, wrote the case presentation and discussion sections. Francesco Patti wrote the background section and revised the manuscript critically for important

Participant perspectives of a home-based palliative approach for people with severe multiple sclerosis: A qualitative study

Grazia Grasso, Francesco Patti, Paola Zaratin, Mario Alberto Battaglia, Alessandra Solari. 16 / 17 1. Kremenchutzky M , Rice GP , Baskerville J , Wingerchuk DM , Ebers GC . The natural history of multiple

Efficacy of fingolimod and interferon beta-1b on cognitive, MRI, and clinical outcomes in relapsing–remitting multiple sclerosis: an 18-month, open-label, rater-blinded, randomised, multicentre study (the GOLDEN study)

here, in order of recruitment): Italian centres (1) Francesco Patti and Clara Grazia Chisari, Department of Medical, Surgery Science and Advanced Technology “GF Ingrassia”, Section of Neurosciences—MS

Development of a Short Version of MSQOL-54 Using Factor Analysis and Item Response Theory

Background The Multiple Sclerosis Quality of Life-54 (MSQOL-54, 52 items grouped in 12 subscales plus two single items) is the most used MS specific health related quality of life inventory. Objective To develop a shortened version of the MSQOL-54. Methods MSQOL-54 dimensionality and metric properties were investigated by confirmatory factor analysis (CFA) and Rasch modelling...

Lights and Shadows of Cyclophosphamide in the Treatment of Multiple Sclerosis

October 2010; Revised 29 December 2010; Accepted 19 January 2011 Academic Editor: D. N. Bourdette Copyright © 2011 Francesco Patti and Salvatore Lo Fermo. This is an open access article distributed

Lights and Shadows of Cyclophosphamide in the Treatment of Multiple Sclerosis

28 October 2010; Revised 29 December 2010; Accepted 19 January 2011 Academic Editor: D. N. Bourdette Copyright © 2011 Francesco Patti and Salvatore Lo Fermo. This is an open access article

Cognitive impairment and “invisible symptoms” are not associated with CCSVI in MS

Background We investigated the association between chronic cerebrospinal venous insufficiency (CCSVI) and cognitive impairment (CI) in multiple sclerosis (MS). Moreover, we evaluated the association between CCSVI and other frequent self-reported MS symptoms. Methods We looked at the presence of CI in incident MS patients with CCVSI in a population-based cohort of Catania, Italy...

Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study)

: Silvia Messina, Claudio Solaro, Francesco Patti. Data curation: Silvia Messina, Claudio Solaro, Francesco Patti. Formal analysis: Silvia Messina, Isabella Righini, Roberto Bergamaschi, Simona Bonavita ... Granata, Mario Zappia, Francesco Patti. Project administration: Francesco Patti. Validation: Mario Zappia, Francesco Patti. Writing ± original draft: Silvia Messina, Francesco Patti. 8 / 10 Writing

The Use of Immunosuppressant Therapy for Multiple Sclerosis in Italy: A Multicenter Retroprospective Study

Introduction Immunosuppressive agents (ISA) have been used in multiple sclerosis (MS) for decades, frequently as off label licensed therapies. Given the new MS treatment landscape, what place do ISA have in combating MS? Methods We conducted a retrospective multicentre study to investigate the frequency of ISA prescription in 17 Italian MS centres, and to describe the clinical...

Home-based palliative approach for people with severe multiple sclerosis and their carers: study protocol for a randomized controlled trial

Background Preliminary evidence suggests that palliative care may be useful for people with severe multiple sclerosis (MS). The aim of this study is to determine the effectiveness of a home-based palliative approach (HPA) for people with severe MS and their carers. Methods/design This is a single-blind randomized controlled trial with a nested qualitative study. Seventy-five...

Subcutaneous Interferon β-1a May Protect against Cognitive Impairment in Patients with Relapsing–Remitting Multiple Sclerosis: 5-Year Follow-up of the COGIMUS Study

the inherently better prognosis associated with female sex in MS. - Competing Interests: Francesco Patti has received research funding from the University of Catania and Fondazione Italiana Sclerosi

Multiple Sclerosis in the Mount Etna Region: Possible Role of Volcanogenic Trace Elements

Background Trace elements have been hypothesised to be involved in the pathogenesis of Multiple Sclerosis and volcanic degassing is the major natural sources of trace elements. Both incidence of Multiple Sclerosis in Catania and volcanic activity of Mount Etna have been significantly increased during the last 30 years. Due to prevailing trade winds direction, volcanic gases from...

Unmet Needs of People with Severe Multiple Sclerosis and Their Carers: Qualitative Findings for a Home-Based Intervention

Background Few data on services for people with severe multiple sclerosis (MS) are available. The Palliative Network for Severely Affected Adults with MS in Italy (PeNSAMI) developed a home palliative care program for MS patients and carers, preceded by a literature review and qualitative study (here reported). Objective To identify unmet needs of people with severe MS living at...

Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving interferon β-1a in the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study

Stefano Bastianello 0 Elisabetta Giugni Maria Pia Amato Maria-Rosalia Tola Maria Trojano Stefano Galletti Giacomo Luccichenti Mario Quarantelli Orietta Picconi Francesco Patti for the COGIMUS study

Lesion Load May Predict Long-Term Cognitive Dysfunction in Multiple Sclerosis Patients

lectures from Novartis; Prof. Tedeschi has received travel payment from MerckSerono, Novartis, Biogen Idec and Teva and honoraria for scientific lectures from Novartis, Teva and Biogen Idec. Francesco Patti

Multiple Sclerosis and CCSVI: A Population-Based Case Control Study

Background Chronic cerebrospinal venous insufficiency (CCSVI) has been associated to multiple sclerosis (MS). Objective To evaluate the possible association between CCSVI and MS, using a population-based control design. Methods A random cohort of 148 incident MS patients were enrolled in the study. We have also studied 20 patients with clinically isolated syndrome (CIS), 40...