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6 papers found.
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Adjuvant treatment with the bacterial lysate (OM-85) improves management of atopic dermatitis: A randomized study

Background Environmental factors play a major role on atopic dermatitis (AD) which shows a constant rise in prevalence in western countries over the last decades. The Hygiene Hypothesis suggesting an inverse relationship between incidence of infections and the increase in atopic diseases in these countries, is one of the working hypothesis proposed to explain this trend...

Sweet’s syndrome revealed by oral pustulosis

Introduction: Neutrophilic dermatoses are conditions characterized by a dermal neutrophilic infiltration associated with variable leukocytoclasia. Oral involvement occurs but is rare and is of less importance than the cutaneous involvement. Observation: The case of a 71-year-old man with neutrophilic dermatoses in whom the major manifestations of the disease were recurrent oral...

Correction: Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation

Cell Activation Emeline Laborel-Préneron Pascale Bianchi Franck Boralevi Philippe Lehours Frédérique Fraysse Fanny Morice-Picard Motoyuki Sugai Yusuke Sato'o Cédric Badiou Gérard Lina Anne-Marie Schmitt

Effects of the Staphylococcus aureus and Staphylococcus epidermidis Secretomes Isolated from the Skin Microbiota of Atopic Children on CD4+ T Cell Activation

Interactions between the immune system and skin bacteria are of major importance in the pathophysiology of atopic dermatitis (AD), yet our understanding of them is limited. From a cohort of very young AD children (1 to 3 years old), sensitized to Dermatophagoides pteronyssinus allergens (Der p), we conducted culturomic analysis of skin microbiota, cutaneous transcript profiling...

LEKTI proteolytic processing in human primary keratinocytes, tissue distribution and defective expression in Netherton syndrome

SPINK5, encoding the putative multi-domain serine protease inhibitor LEKTI, was recently identified as the defective gene in the severe autosomal recessive ichthyosiform skin condition, Netherton syndrome (NS). Using monoclonal and polyclonal antibodies, we show that LEKTI is a marker of epithelial differentiation, strongly expressed in the granular and uppermost spinous layers...