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Search: authors:"Gallezot, Jean-Dominique"

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Noradrenergic Activity in the Human Brain: A Mechanism Supporting the Defense Against Hypoglycemia

Hypoglycemia, one of the major factors limiting optimal glycemic control in insulin-treated patients with diabetes, elicits a brain response to restore normoglycemia by activating counterregulation. Animal data indicate that local release of norepinephrine (NE) in the hypothalamus is important for triggering hypoglycemia-induced counterregulatory (CR) hormonal responses.