Advanced search    

Search: authors:"Gareth L. Ackland"

11 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies

. University College London Hospitals NHS Trust, London, United Kingdom: Gareth L Ackland, Robert CM Stephens, Amy Jones, James Otto, Anna Lach, Ana Gutierrez del Arroyo, John Whittle, Laura Gallego Paredes ... , United Kingdom: Pradeep Pradhu, Daniel Hull, Laura Montague. Author Contributions Conceptualization: Gareth L. Ackland. Data curation: Tom E. F. Abbott, Martin Clark, Thomas Owen, Pradeep Prabhu

Vagal determinants of exercise capacity

Marina, Gareth L. Ackland & Alexander V. GourineUCL Centre for Advanced Biomedical Imaging, Division of Medicine, University College London, London WC1E 6DD, UKAsif Machhada & Mark F. LythgoeUniversity ... ScholarSearch for Mark F. Lythgoe in:Nature Research journals • PubMed • Google ScholarSearch for Sergey Kasparov in:Nature Research journals • PubMed • Google ScholarSearch for Gareth L. Ackland in:Nature

Presepsin: solving a soluble (CD14) problem in sepsis?

Gareth L. Ackland John R. Prowle G. L. Ackland ()) sCD14 level was higher when there was subsequent

Distinct cardioprotective mechanisms of immediate, early and delayed ischaemic postconditioning

Cardioprotection against ischaemia/reperfusion injury in mice can be achieved by delayed ischaemic postconditioning (IPost) applied as late as 30 min after the onset of reperfusion. We determined the efficacy of delayed IPost in a rat model of myocardial infarction (MI) and investigated potential underlying mechanisms of this phenomenon. Rats were subjected to 20, 30 or 45 min of...

Preoperative muscle weakness as defined by handgrip strength and postoperative outcomes: a systematic review

Background Reduced muscle strength- commonly characterized by decreased handgrip strength compared to population norms- is associated with numerous untoward outcomes. Preoperative handgrip strength is a potentially attractive real-time, non-invasive, cheap and easy-to-perform "bedside" assessment tool. Using systematic review procedure, we investigated whether preoperative...

Cardiopulmonary Exercise Capacity and Preoperative Markers of Inflammation

threshold.Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Gareth L. Ackland carried out the study design, data collection ... /Health Foundation Clinician Scientist scheme (Gareth L. Ackland); National Institute for Health Research Central and East London Clinical Research Network; Centre for Anesthesia, Critical Care and Pain

Cardiopulmonary Exercise Capacity and Preoperative Markers of Inflammation

threshold.Conflict of Interests The authors declare that there is no conflict of interests regarding the publication of this paper. Authors’ Contribution Gareth L. Ackland carried out the study design, data collection ... /Health Foundation Clinician Scientist scheme (Gareth L. Ackland); National Institute for Health Research Central and East London Clinical Research Network; Centre for Anesthesia, Critical Care and Pain

Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

Blood transfusion in the perioperative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remain incompletely understood. In this study, we explore the hypothesis that...

Perioperative blood transfusion is associated with a gene transcription profile characteristic of immunosuppression: a prospective cohort study

Introduction Blood transfusion in the perioperative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remain incompletely understood. In this study, we explore the...

Novel biomarkers in critical care: utility or futility?

One of the holy grails of modern medicine, across a range of clinical sub-specialties, is establishing highly sensitive and specific biomarkers for various diseases. Significant success has been achieved in some of these clinical areas, most notably identifying high-sensitivity C-reactive peptide, troponin I/T and brain natriuretic peptide as significant prognosticators for both...

Novel biomarkers in critical care: utility or futility?

One of the holy grails of modern medicine, across a range of clinical sub-specialties, is establishing highly sensitive and specific biomarkers for various diseases. Significant success has been achieved in some of these clinical areas, most notably identifying high-sensitivity C-reactive peptide, troponin I/T and brain natriuretic peptide as significant prognosticators for both...