Advanced search    

Search: authors:"Gouke J. Bonsel"

30 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

362 Assessing performance of paediatric intensive care

Performance of a 10 bed paediatric intensive care unit (PICU) in a university children's hospital was assessed in a prospective cohort study of unselected, consequtive admissions. Collected data included primary clinical specialty, PRISM score derived mortality risk, administration of PICU-dependent therapy and vital status at discharge. Effectiveness of care was determined by...

Additive or Sequential Nucleoside Analogue Therapy Compared with Continued Zidovudine Monotherapy in Human Immunodeficiency Virus-Infected Patients with Advanced Disease Does Not Prolong Survival: An Observational Study

To study the effect of sequential or additive use of zalcitabine or didanosine on survival in 308 human immunodeficiency virus-infected patients with advanced disease treated with zidovudine, an observational study using time-dependent Cox proportional hazards models was done. Changing to sequential or additive therapy was based on deterioration of a patient's health status, a...

Antenatal non-medical risk assessment and care pathways to improve pregnancy outcomes: a cluster randomised controlled trial

Social deprivation negatively affects health outcomes but receives little attention in obstetric risk selection. We investigated whether a combination of (1) risk assessment focused on non-medical risk factors, lifestyle factors, and medical risk factors, with (2) subsequent institution of risk-specific care pathways, and (3) multidisciplinary consultation between care providers...

Contribution of Primary Pelvic Organ Prolapse to Micturition and Defecation Symptoms

Objective. To investigate the contribution of Pelvic Organ Prolapse (POP) to micturition and defecation symptoms. Method. Cross-sectional study including 64 women presenting with POP symptoms and 50 controls without POP complaints. Subjects were evaluated using POP-Quantification system, Urinary Distress Inventory, and Defecation Distress Inventory. The MOS SF-36 health survey...

Design and outline of the Healthy Pregnancy 4 All study

Background Promotion of healthy pregnancies has gained high priority in the Netherlands because of the relatively unfavourable perinatal health outcomes. In response a nationwide study Healthy Pregnancy 4 All was initiated. This study combines public health and epidemiologic research to evaluate the effectiveness of two obstetric interventions before and during pregnancy: (1...

Different settings of place of midwife-led birth: evaluation of a midwife-led birth centre

Objectives The claimed advantages of home deliveries, including fewer medical interventions, are potentially counter balanced by the small additional risk on perinatal adverse outcome compared to hospital deliveries in low risk women. Homelike birth centres have been proposed a new setting for low risk women combining the advantages of home and hospital, resulting in lower...

Effectiveness of score card-based antenatal risk selection, care pathways, and multidisciplinary consultation in the Healthy Pregnancy 4 All study (HP4ALL): study protocol for a cluster randomized controlled trial

Background Promotion of healthy pregnancies has gained high priority in the Netherlands because of relatively unfavorable perinatal outcomes. In response, a nationwide study, ‘Healthy Pregnancy 4 All’ (HP4ALL), has been initiated. Part of this study involves systematic and broadened antenatal risk assessment (the Risk Assessment substudy). Risk selection in current clinical...

Evaluating the discriminatory power of EQ-5D, HUI2 and HUI3 in a US general population survey using Shannon’s indices

Mathieu F. (Bas) Janssen 0 Erwin Birnie 0 Gouke J. Bonsel 0 0 M. F. (Bas) Janssen (&) E. Birnie G. J. Bonsel Public Health Epidemiology, Department of Social Medicine, Academic Medical Center

Expectant management versus surgical evacuation in first trimester miscarriage: health-related quality of life in randomized and non-randomized patients

BACKGROUND: Expectant management, although less effective, is an alternative treatment option for surgical evacuation in women with a miscarriage. We assessed health-related quality of life (HRQL) differences over time between expectant and surgical management in women with a miscarriage. METHODS: Women with a miscarriage were randomized to either expectant (n = 64) or surgical...

Geographical, Ethnic and Socio-Economic Differences in Utilization of Obstetric Care in the Netherlands

J. Borsboom Jashvant Poeran Eric A. P. Steegers 0 Gouke J. Bonsel 0 0 Department of Obstetrics and Gynaecology, Division of Obstetrics and Prenatal Medicine, Erasmus University Medical Centre

Individual accumulation of heterogeneous risks explains perinatal inequalities within deprived neighbourhoods

Dutch’ figures on perinatal mortality and morbidity are poor compared to EU-standards. Considerable within-country differences have been reported too, with decreased perinatal health in deprived urban areas. We investigated associations between perinatal risk factors and adverse perinatal outcomes in 7,359 pregnant women participating in population-based prospective cohort study...

Individual differences in the use of the response scale determine valuations of hypothetical health states: an empirical study

Background The effects of socio-demographic characteristics of the respondent, including age, on valuation scores of hypothetical health states remain inconclusive. Therefore, we analyzed data from a study designed to discriminate between the effects of respondents' age and time preference on valuations of health states to gain insight in the contribution of individual response...

Is EQ-5D-5L Better Than EQ-5D-3L? A Head-to-Head Comparison of Descriptive Systems and Value Sets from Seven Countries

. Janssen, Gouke J. Bonsel and Nan Luo) are members of the EuroQol Group. Data availability statement All data analysed in this study are stored at the central data archive of the EuroQol Research Foundation

Long term costs and effects of reducing the number of twin pregnancies in IVF by single embryo transfer: the TwinSing study

Mirjam MJ van Heesch 0 Gouke J Bonsel John CM Dumoulin Johannes LH Evers Mark AHBM van der Hoeven Johan L Severens Ramon HM Dykgraaf Fulco van der Veen Nino Tonch Willianne LDM Nelen Piet van

Management of miscarriage: a randomized controlled trial of expectant management versus surgical evacuation

BACKGROUND: In many countries, surgical uterine evacuation is the standard treatment for women with a miscarriage, but expectant management has been advocated as an alternative. The choice between the two options cannot be based on published evidence alone, because randomized clinical trials are scarce while generalizability of findings to patients with a strong preference for...

Maternal health-related quality of life after induction of labor or expectant monitoring in pregnancy complicated by intrauterine growth retardation beyond 36 weeks

Objective Pregnancies complicated by intrauterine growth retardation (IUGR) beyond 36 weeks of gestation are at increased risk of neonatal morbidity and mortality. Optimal treatment in IUGR at term is highly debated. Results from the multicenter DIGITAT (Disproportionate Intrauterine Growth Intervention Trial At Term) trial show that induction of labor and expectant monitoring...

Measuring Client Experiences in Maternity Care under Change: Development of a Questionnaire Based on the WHO Responsiveness Model

Background Maternity care is an integrated care process, which consists of different services, involves different professionals and covers different time windows. To measure performance of maternity care based on clients' experiences, we developed and validated a questionnaire. Methods and Findings We used the 8-domain WHO Responsiveness model, and previous materials to develop a...

Multiplex ligation-dependent probe amplification versus karyotyping in prenatal diagnosis: the M.A.K.E. study

Background In the past 30 years karyotyping was the gold standard for prenatal diagnosis of chromosomal aberrations in the fetus. Traditional karyotyping (TKT) has a high accuracy and reliability. However, it is labor intensive, the results take 14–21 days, the costs are high and unwanted findings such as abnormalities with unknown clinical relevance are not uncommon. These...

Obstetrical outcome valuations by patients, professionals, and laypersons: differences within and between groups using three valuation methods

Background Decision-making can be based on treatment preferences of the patient, the doctor, or by guidelines based on lay people's preferences. We compared valuations assigned by three groups: patients, obstetrical care professionals, and laypersons, for health states involving both mother and (unborn) child. Our aim was to compare the valuations of different groups using...

Obtaining insurance after DNA diagnostics: a survey among hypertrophic cardiomyopathy mutation carriers

Birnie Gouke J Bonsel Arthur AM Wilde Ellen MA Smets Hypertrophic cardiomyopathy (HCM) is a common hereditary heart disease associated with increased mortality. Disclosure of DNA test results may have