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8 papers found.
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Association between previous schistosome infection and incident hyperuricemia: A prospective cohort study in China

Author Contributions Conceptualization: Chen Dong. The authors thank all the investigators who participated in the study and all the patients. Data curation: Guangli Wang, Yang Jing, Yi Ding, Jing Qiu ... . Formal analysis: Guangli Wang, Yang Jing. Funding acquisition: Hui Zhou, Chen Dong. Investigation: Guangli Wang, Yang Jing, Hui Zhou, Yi Ding, Jing Qiu. Methodology: Haiyong Hua, Chen Dong. Project

TFPI-2 suppresses breast cancer cell proliferation and invasion through regulation of ERK signaling and interaction with actinin-4 and myosin-9

TFPI-2 has been recognized as a potent tumor suppressor gene. Low expression of TFPI-2 results in enhanced growth and metastasis of a variety of human tumors. In the present study, we investigated the mechanism responsible for the tumor suppressive effect of TFPI-2. Overexpression of TFPI-2 decreased phosphorylation of ERK1/2 and the translocation of p-ERK1/2 from cytoplasm into...

Anti-asthmatic effect of pitavastatin through aerosol inhalation is associated with CD4+ CD25+ Foxp3+ T cells in an asthma mouse model

Statins are competitive inhibitors of 3-hydroxy-3-methylglutaryl-CoA (HMG-A) reductase, and studies have shown that statins also have anti-inflammatory and immunomodulatory properties. The purpose of this study was to investigate the anti-asthmatic effects of pitavastatin, a type of statin, in an asthma mouse model. Mice were sensitized and challenged with ovalbumin (OVA) to...

Localization of TFPI-2 in the nucleus modulates MMP-2 gene expression in breast cancer cells

TFPI-2 has recently been recognized as a tumor suppressor, which not only plays a fundamental role in modulation of ECM integrity, but also involves the regulation of many oncogenes. In this study, we investigated the potential mechanism of TFPI-2 in the suppression of breast cancer growth and invasion. We showed that, with either over-expression of TFPI-2 or after treatment with...

Microbial Degradation of Acetamiprid by Ochrobactrum sp. D-12 Isolated from Contaminated Soil

Neonicotinoid insecticides are one of the most important commercial insecticides used worldwide. The potential toxicity of the residues present in environment to humans has received considerable attention. In this study, a novel Ochrobactrum sp. strain D-12 capable of using acetamiprid as the sole carbon source as well as energy, nitrogen source for growth was isolated and...

Thermochemical sulfate reduction in fossil Ordovician deposits of the Majiang area: Evidence from a molecular-marker investigation

The main reservoirs of Majiang fossil deposits consist of the Silurian Wengxiang group, dominantly sandstones, and the Ordovician Honghuayuan formation, dominantly carbonate rocks, and the Lower Cambrian Niutitang Formation mudstones serve as the major source rocks. Thermochemical sulfate reduction (TSR) might have taken place in the Paleozoic marine carbonate oil pools, as...

New consideration of atmospheric refraction in laser ranging data

In this paper we reconsider the formulae of tropospheric refraction correction for the Satellite Laser Range technique. From the expansion of the complementary error function, a new continued fraction form of the mapping function at optical frequencies is derived. The correction terms related to the operation frequency of the laser beam are considered in both the zenith delay and...

A comparison of different tropospheric mapping functions by elevation cut-off tests

The uncertainties in the ground surface meteorological parameters should be introduced into atmospheric mapping function models, such as CfA2.2 and UNSW931, etc. Although these models have been developed by the ray-tracing method according to a given tropospheric profile, these kinds of atmospheric modelling errors will have an effect on the estimates of coordinates for very long...