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Pulmonary Effects of Adjusting Tidal Volume to Actual or Ideal Body Weight in Ventilated Obese Mice

information AffiliationsINSERM U955, Université Paris Est (UPEC), Faculté de Médecine, 94000, Créteil, FranceElise Guivarch, Guillaume Voiriot, Anahita Rouzé, Stéphane Kerbrat, Bernard Maitre & Jorge ... Guillaume Voiriot in:Nature Research journals • PubMed • Google Scholar Search for Anahita Rouzé in:Nature Research journals • PubMed • Google Scholar Search for Stéphane Kerbrat in:Nature Research journals

Clinical features and outcome of patients with acute respiratory failure revealing anti-synthetase or anti-MDA-5 dermato-pulmonary syndrome: a French multicenter retrospective study

BackgroundAnti-synthetase (AS) and dermato-pulmonary associated with anti-MDA-5 antibodies (aMDA-5) syndromes are near one of the other autoimmune inflammatory myopathies potentially responsible for severe acute interstitial lung disease. We undertook a 13-year retrospective multicenter study in 35 French ICUs in order to describe the clinical presentation and the outcome of...

Prevalence of respiratory viruses among adults, by season, age, respiratory tract region and type of medical unit in Paris, France, from 2011 to 2016

, Conceptualization: Benoit Visseaux, Charles Burdet, Guillaume Voiriot, FrancËois-Xavier Lescure, Olivier Brugière, Bruno Crestani, Enrique Casalino, Charlotte Charpentier, Diane Descamps, Jean-FrancËois Timsit ... , Yazdan Yazdanpanah, Nadhira Houhou-Fidouh. Data curation: Benoit Visseaux, Charles Burdet, Guillaume Voiriot, Taous Chougar, Nadhira Houhou-Fidouh. Formal analysis: Benoit Visseaux, Charles Burdet, Taous

Systematic overdosing of oxa- and cloxacillin in severe infections treated in ICU: risk factors and side effects

Background Oxacillin and cloxacillin are the most frequently used penicillins for the treatment of severe methicillin-susceptible Staphylococcus aureus infections in intensive care units (ICUs), especially endocarditis. International recommendations do not suggest any adaptation of the dosage in case of renal impairment. We wanted to assess the risk factors for overdosing in ICU...

Viral-bacterial coinfection affects the presentation and alters the prognosis of severe community-acquired pneumonia

Background Multiplex polymerase chain reaction (mPCR) enables recovery of viruses from airways of patients with community-acquired pneumonia (CAP), although their clinical impact remains uncertain. Methods Among consecutive adult patients who had undergone a mPCR within 72 hours following their admission to one intensive care unit (ICU), we retrospectively included those with a...

Treatment of bloodstream infections in ICUs

Bloodstream infections (BSIs) are frequent in ICU and is a prognostic factor of severe sepsis. Community acquired BSIs usually due to susceptible bacteria should be clearly differentiated from healthcare associated BSIs frequently due to resistant hospital strains. Early adequate treatment is key and should use guidelines and direct examination of samples performed from the...

French Intensive Care Society, International congress – Réanimation 2016

-Helali, Alban Le Monnier, Eric Magalhaes, Aguila Radjou, Roland Smonig, Jean-François Soubirou, Guillaume Voiriot, Romain Sonneville, Lila Bouadma, Bruno Mourvillier O8 Amikacin peak concentrations in