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Idiopathic atrial fibrillation patients rapidly outgrow their low thromboembolic risk: a 10-year follow-up study

BackgroundHealthy atrial fibrillation (AF) patients will eventually outgrow their low thromboembolic risk. The purpose of this study is to compare the development of cardiovascular disease in healthy AF patients as compared to healthy sinus rhythm patients and to assess appropriate anticoagulation treatment.MethodsForty-one idiopathic paroxysmal AF patients (56 ± 10 years, 66...

Optimal long-term antithrombotic management of atrial fibrillation: life cycle management

Optimal antithrombotic management of atrial fibrillation equals balancing between prevention of arterial thromboembolism, predominantly ischaemic stroke, and haemorrhagic complications. Over time different antithrombotic agents and strategies have been developed. At present, non-vitamin K antagonist oral anticoagulants (NOACs) are the first-line therapy for stroke prevention in...

Stroke risk in patients with device-detected atrial high-rate episodes

Cardiovascular implantable electronic devices (CIEDs) can detect atrial arrhythmias, i. e. atrial high-rate episodes (AHRE). The thrombo-embolic risk in patients showing AHRE appears to be lower than in patients with clinical atrial fibrillation (AF) and it is unclear whether the former will benefit from oral anticoagulants. Based on currently available evidence, it seems...

Real-life use of Rivaroxaban in the Netherlands: data from the Xarelto for Prevention of Stroke in Patients with Atrial Fibrillation (XANTUS) registry

Background The Xarelto for Prevention of Stroke in Patients with Atrial Fibrillation (XANTUS) registry investigated the safety and efficacy of the factor Xa inhibitor rivaroxaban. We studied the Dutch XANTUS cohort to a ssess drug safety and prescription patterns in the Netherlands. Methods The XANTUS registry was designed as a European prospective, observational study among...

Electrical cardioversion in healthy pregnant women: safe yes, but needed?

H. J. G. M. Crijns 0 0 H. J. G. M. Crijns ( 1 ) Department of Cardiology, Maastricht University Medical Centre , Maastricht, the Netherlands - Sustained maternal arrhythmias during pregnancy that

Routine versus aggressive upstream rhythm control for prevention of early atrial fibrillation in heart failure: background, aims and design of the RACE 3 study

7 8 9 10 11 0 F. F. Willems Department of Cardiology, Rijnstate Hospital , Arnhem/Velp, the Netherlands 1 H. J. G. M. Crijns Department of Cardiology, Maastricht University Medical Center , Maastricht

Haemodynamic bradycardia in tachycardiomyopathy

M. Mafirad Y. Blaauw J. M. van Opstal H. J. G. M. Crijns - A 44-year-old man presented with a 6-month history of progressive dyspnoea (NYHA class III). The electrocardiogram showed sinus rhythm

Coronary artery-bronchial artery fistulas: report of two Dutch cases with a review of the literature

Background Coronary bronchial artery fistulas (CBFs) are rare anomalies, which may be isolated or associated with other disorders. Materials and methods Two adult patients with CBFs are described and a PubMed search was performed using the keywords “coronary bronchial artery fistulas” in the period from 2008 to 2013. Results Twenty-seven reviewed subjects resulting in a total of...