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119 papers found.
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Positive nonsentinel lymph nodes are associated with poor survival in breast cancer: results from a retrospective study

PurposeThe prognostic value of nonsentinel lymph-node (NSLN) status in breast cancer remains unclear. This study was designed to investigate the prognostic value of NSLN status in SLN-positive breast cancer.MethodsRetrospective 873 consecutive primary breast cancer patients from a single institution who were SLN-positive and underwent axillary lymph-node dissection (ALND) were...

Neural Substrates of Word Generation during Stroke Recovery: The Influence of Cortical Hypoperfusion

Several studies have demonstrated reorganization of cognitive and motor function caused by stroke. This study examined the influence of hypoperfused brain regions, in addition to the area of the infarct itself, on reorganization of the cognitive processes underlying word generation in stroke patients. In addition, we also sought to determine the influence of hypoperfusion on the...

Five-year clinical follow-up of the STENTYS self-apposing stent in complex coronary anatomy: a single-centre experience with report of specific angiographic indications

this device in lesions with vessel diameter variance [ 29 ]. Funding The authors received no specific funding for this work. Conflict of interest H. Lu, R.J. Bekker, M.J. Grundeken, P. Woudstra, J.J

Size effect on atomic structure in low-dimensional Cu-Zr amorphous systems

The size effect on atomic structure of a Cu64Zr36 amorphous system, including zero-dimensional small-size amorphous particles (SSAPs) and two-dimensional small-size amorphous films (SSAFs) together with bulk sample was investigated by molecular dynamics simulations. We revealed that sample size strongly affects local atomic structure in both Cu64Zr36 SSAPs and SSAFs, which are...

Regulation of spindle integrity and mitotic fidelity by BCCIP

Centrosomes together with the mitotic spindle ensure the faithful distribution of chromosomes between daughter cells, and spindle orientation is a major determinant of cell fate during tissue regeneration. Spindle defects are not only an impetus of chromosome instability but are also a cause of developmental disorders involving defective asymmetric cell division. In this work, we...

Comparison of effectiveness and safety between conbercept and ranibizumab for treatment of neovascular age-related macular degeneration. A retrospective case-controlled non-inferiority multiple center study

, Heilongjiang, PR ChinaJ Cui, H Lu, H Dong, L Wang, D Wei & H ChenDepartment of Orthopedic Surgery and BME-Campbell Clinic, University of Tennessee Health Science Center, Memphis, TN, USAJ Cui, Y Jiao & W ... for J Cui in:Nature Research journals • PubMed • Google ScholarSearch for D Sun in:Nature Research journals • PubMed • Google ScholarSearch for H Lu in:Nature Research journals • PubMed • Google

Prevention and treatment of bone loss and fractures in patients undergoing a hematopoietic stem cell transplant: a systematic review and meta-analysis

The most effective method to prevent and treat bone loss following hematopoietic stem cell transplantation (HSCT) remains uncertain. We conducted a comprehensive search in four electronic databases until August 2015. We retrieved articles describing patients with bone loss or fractures who received HSCT. Controlled trials, with a follow-up period of at least 12 months, were...

Platypnoea-orthodeoxia syndrome, an underdiagnosed cause of hypoxaemia: four cases and the possible underlying mechanisms

Medicine, VU University Medical Center , Amsterdam , The Netherlands 1 T.C. Konings Department of Cardiology, VU University Medical Center , Amsterdam , The Netherlands 2 R.J. de Winter () · M. Nassif · H ... . Lu · B.J. Bouma · B. Straver · N.A. Blom · A.P.C.M. Backx · M. Groenink · S.M. Boekholdt · B.J.M. Mulder Department of Cardiology, Cardiac Catheterization Laboratory, Academic Medical Center-University

Cadherin 6 is activated by Epstein–Barr virus LMP1 to mediate EMT and metastasis as an interplay node of multiple pathways in nasopharyngeal carcinoma

- 247 ( 2014 ). 9. Zeng , L. , Cui , J. , Wu , H. & Lu , Q. The emerging role of circulating microRNAs as biomarkers in autoimmune diseases . Autoimmunity 47 , 419 - 429 ( 2014 ). 10. Deng , X. et al. The

Quasispecies evolution of the prototypical genotype 1 porcine reproductive and respiratory syndrome virus early during in vivo infection is rapid and tissue specific

selection . Proc Natl Acad Sci USA 109 : 12980 - 12985 51. Yu D , Lv J , Sun Z , Zheng H , Lu J , Yuan S ( 2009 ) Reverse genetic manipulation of the overlapping coding regions for structural proteins of the

Stripes developed at the strong limit of nematicity in FeSe film

A single monolayer of iron selenide grown on strontium titanate shows an impressive enhancement of superconductivity compared with the bulk1, as well as a novel Fermi surface topology2,3,4,5, extreme two-dimensionality, and the possibility of phonon-enhanced electron pairing1,5. For films thicker than one unit cell, however, the electronic structure is markedly different, with a...

Topological Properties of Atomic Lead Film with Honeycomb Structure

-Guangdong Government Supercomputer Application Program(nsfc2015_339) Author information AffiliationsSchool of Materials Science and Engineering, Zhejiang University, Hangzhou, 310027, ChinaY. H. Lu, D ... . Zhou & J. Z. JiangState Key Laboratory of Silicon Materials, Zhejiang University, Hangzhou 310027, ChinaY. H. Lu, D. Zhou & J. Z. JiangCollege of Electrical Engineering, Zhejiang University, Hangzhou

Relationship between atrial septal defects and asthma-like dyspnoea: the impact of transcatheter closure

remains to be further investigated in prospective studies. Funding None. Conflict of interest M. Nassif, C.B.B.C. Heuschen, H. Lu, B.J. Bouma, R.P. van Steenwijk, P.J. Sterk, B.J.M. Mulder and R. J. de

Whole Mitogenomes Reveal the History of Swamp Buffalo: Initially Shaped by Glacial Periods and Eventually Modelled by Domestication

in:Nature Research journals • PubMed • Google Scholar Search for H. Lu in:Nature Research journals • PubMed • Google Scholar Search for L. Caporali in:Nature Research journals • PubMed • Google Scholar

Effect of low irradiance on the photosynthetic performance and spiking of Phalaenopsis

Lowering irradiance can delay the flower stalk, i.e., spike development, in order to schedule flowering time of Phalaenopsis; however, the effect on photosynthetic performance and spiking inhibition remains poorly understood. We compared light and shade treatments of Phalaenopsis aphrodite subsp. formosana in order to determine how limiting light affects day-night changes in the...

Antifreeze in the hot core of Orion - First detection of ethylene glycol in Orion-KL

Context. Ices are present in comets and in the mantles of interstellar grains. Their chemical composition has been indirectly derived by observing molecules released in the gas phase, when comets approach the sun and when ice mantles are sublimated or destroyed, e.g. in the hot cores present in high-mass, star-forming regions. Comparison of these chemical compositions sheds light...

Mastectomy rates remain high in Singapore and are not associated with poorer survival after adjusting for age

Recent reports have suggested that women undergoing mastectomy, instead of wide local excision (WLE) for Stage I and II breast cancers have poorer overall survival. This is particularly important in our setting where mastectomy rates are high. In this study, we evaluated the trends in mastectomy and WLE over a 10-year period at a single institute, identified factors more common...

Quantitative Mapping of Matrix Content and Distribution across the Ligament-to-Bone Insertion

The interface between bone and connective tissues such as the Anterior Cruciate Ligament (ACL) constitutes a complex transition traversing multiple tissue regions, including non-calcified and calcified fibrocartilage, which integrates and enables load transfer between otherwise structurally and functionally distinct tissue types. The objective of this study was to investigate...

Downregulation of COMMD1 by miR-205 promotes a positive feedback loop for amplifying inflammatory- and stemness-associated properties of cancer cells

Sustained activation of nuclear factor-κB (NF-κB) in cancer cells has been shown to promote inflammation, expansion of cancer stem cell (CSC) population, and tumor development. In contrast, recent studies reveal that CSCs exhibit increased inflammation due to constitutive NF-κB activation; however, the underlying molecular mechanism remains unclear. In the present study, the...