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Search: authors:"Hafiz M. Ahmad"

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Analysis of microRNA transcriptome by deep sequencing of small RNA libraries of peripheral blood

Background MicroRNAs are a class of small non-coding RNAs that regulate mRNA expression at the post - transcriptional level and thereby many fundamental biological processes. A number of methods, such as multiplex polymerase chain reaction, microarrays have been developed for profiling levels of known miRNAs. These methods lack the ability to identify novel miRNAs and accurately...

Analysis of the microRNA transcriptome and expression of different isomiRs in human peripheral blood mononuclear cells

MicroRNAs (miRNAs) have been recognized as one of the key regulatory non-coding RNAs that are involved in a number of basic cellular processes. miRNA expression profiling helps to identify miRNAs that could serve as biomarkers. Next generation sequencing (NGS) platforms provide the most effective way of miRNA profiling, particularly as expression of different isoforms of miRNA...

MicroRNA-191, an estrogen-responsive microRNA, functions as an oncogenic regulator in human breast cancer

Estrogen- and microRNA-mediated gene regulation play a crucial role in breast cancer biology. However, a functional link between the two major players remains unclear. This study reveals miR-191 as an estrogen-inducible onco-miR in breast cancer, which promotes several hallmarks of cancer including enhanced cell proliferation, migration, chemoresistance and survival in tumor...

HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment.

Delhi, India-110016Shibu Chameettachal & Sourabh Ghosh AuthorsSearch for Neha Nagpal in:Nature Research journals • PubMed • Google ScholarSearch for Hafiz M. Ahmad in:Nature Research journals • PubMed