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Genome-wide identification of the fatty acid desaturases gene family in four Aspergillus species and their expression profile in Aspergillus oryzae

Fatty acid desaturases play a key role in producing polyunsaturated fatty acids by converting single bonds to double bonds. In the present study, a total of 13, 12, 8 and 8 candidate fatty acid desaturases genes were identified in the Aspergillus oryzae, Aspergillus flavus, Aspergillus fumigatus and Aspergillus nidulans genomes through database searches, which were classified...

Cloud Base Height Estimation from ISCCP Cloud-Type Classification Applied to A-Train Data

Cloud base height (CBH) is an important cloud macro parameter that plays a key role in global radiation balance and aviation flight. Building on a previous algorithm, CBH is estimated by combining measurements from CloudSat/CALIPSO and MODIS based on the International Satellite Cloud Climatology Project (ISCCP) cloud-type classification and a weighted distance algorithm...

Cloud Base Height Estimation from ISCCP Cloud-Type Classification Applied to A-Train Data

Cloud base height (CBH) is an important cloud macro parameter that plays a key role in global radiation balance and aviation flight. Building on a previous algorithm, CBH is estimated by combining measurements from CloudSat/CALIPSO and MODIS based on the International Satellite Cloud Climatology Project (ISCCP) cloud-type classification and a weighted distance algorithm...

Cloud Base Height Estimation from ISCCP Cloud-Type Classification Applied to A-Train Data

Cloud base height (CBH) is an important cloud macro parameter that plays a key role in global radiation balance and aviation flight. Building on a previous algorithm, CBH is estimated by combining measurements from CloudSat/CALIPSO and MODIS based on the International Satellite Cloud Climatology Project (ISCCP) cloud-type classification and a weighted distance algorithm...

Coulombic-enhanced hetero radical pairing interactions

, Yang Zhang, Ning Cao, Xin Li, Shuoqing Zhang, Renfeng Du, Zhenni Ye, Yan Wang, Fahe Cao, Haoran Li, Xin Hong & Hao LiDepartment of Chemistry, Hubei Collaborative Innovation Center for Advanced Organic ... Scholar Search for Fahe Cao in:Nature Research journals • PubMed • Google Scholar Search for Haoran Li in:Nature Research journals • PubMed • Google Scholar Search for Xin Hong in:Nature Research journals

Drug screening of cancer cell lines and human primary tumors using droplet microfluidics

Precision Medicine in Oncology requires tailoring of therapeutic strategies to individual cancer patients. Due to the limited quantity of tumor samples, this proves to be difficult, especially for early stage cancer patients whose tumors are small. In this study, we exploited a 2.4 × 2.4 centimeters polydimethylsiloxane (PDMS) based microfluidic chip which employed droplet...

Identification of a heterologous cellulase and its N-terminus that can guide recombinant proteins out of Escherichia coli

Background The Gram-negative bacterium Escherichia coli has been widely used as a cell factory for the production of proteins and specialty chemicals because it is the best characterized host with many available expression and regulation systems. However, recombinant proteins produced in Escherichia coli are generally intracellular and often found in the form of inclusion bodies...

Friend or foe: the role of microRNA in chemotherapy resistance

Chemotherapy has been widely used in treating cancer patients. Despite the tremendous progress in cancer treatment achieved during the last decades, drug resistance still accounts for most of the tumor relapses in chemotherapy-treated patients. Emerging evidence shows that microRNAs play an important role in regulating the drug sensitivity of tumor cells. However, the mechanism...

Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

MicroRNAs (miRNA) precursor (pre-miRNA) molecules can be processed to release a miRNA/miRNA* duplex. In the canonical model of miRNA biogenesis, one strand of the duplex is thought to be the biologically active miRNA, whereas the other strand is thought to be inactive and degraded as a carrier or passenger strand called miRNA* (miRNA star). However, recent studies have revealed...

Anticancer Activity of Amauroderma rude

More and more medicinal mushrooms have been widely used as a miraculous herb for health promotion, especially by cancer patients. Here we report screening thirteen mushrooms for anti-cancer cell activities in eleven different cell lines. Of the herbal products tested, we found that the extract of Amauroderma rude exerted the highest activity in killing most of these cancer cell...