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Search: authors:"Heba N. Nowyhed"

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ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

ABCA7 is an ABC transporter expressed on the plasma membrane, and actively exports phospholipid complexes from the cytoplasmic to the exocytoplasmic leaflet of membranes. Invariant NKT (iNKT) cells are a subpopulation of T lymphocytes that recognize glycolipid antigens in the context of CD1d-mediated antigen presentation. In this study, we demonstrate that ABCA7 regulates the...

The Nuclear Receptor Nr4a1 Controls CD8 T Cell Development Through Transcriptional Suppression of Runx3

 & Catherine C. Hedrick AuthorsSearch for Heba N. Nowyhed in:Nature Research journals • PubMed • Google ScholarSearch for Tridu R. Huynh in:Nature Research journals • PubMed • Google ScholarSearch for Amy