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The effects of a pre-conception lifestyle intervention in women with obesity and infertility on perceived stress, mood symptoms, sleep and quality of life

involved in the LIFEstyle study and follow-up visit. Author Contributions Conceptualization: Ben Willem J. Mol, Henk Groen, Annemieke Hoek, Tessa J. Roseboom. Formal analysis: Lotte van Dammen. Funding ... , Henk Groen, Annemieke Hoek, Tessa J. Roseboom. 11 / 13 12 / 13 1. Hales CM , Carroll MD , Fryar CD , Ogden CL . Prevalence of obesity among adults and youth: United States, 2015-2016 NCHS data brief

A lifestyle intervention improves sexual function of women with obesity and infertility: A 5 year follow-up of a RCT

, Cornelieke van de Beek, Ben Willem J. Mol, Annemieke Hoek, Ellen Laan, Tessa J. Roseboom. Data curation: Vincent Wekker, Matty D. A. Karsten, Cornelieke van de Beek, Henk Groen. Formal analysis: Vincent ... Wekker, Matty D. A. Karsten, Henk Groen. Funding acquisition: Henk Groen, Ben Willem J. Mol, Annemieke Hoek, Tessa J. Roseboom. Investigation: Vincent Wekker, Matty D. A. Karsten, Rebecca C. Painter

Determinants of successful lifestyle change during a 6-month preconception lifestyle intervention in women with obesity and infertility

PurposeTo identify demographic, (bio)physical, behavioral, and psychological determinants of successful lifestyle change and program completion by performing a secondary analysis of the intervention arm of a randomized-controlled trial, investigating a preconception lifestyle intervention.MethodsThe 6-month lifestyle intervention consisted of dietary counseling, physical activity...

Impact of Muscarinic M3 Receptor Antagonism on the Risk of Type 2 Diabetes in Antidepressant-Treated Patients: A Case-Controlled Study

BackgroundM3 muscarinic receptor antagonism has been associated with glucose intolerance and disturbance of insulin secretion.ObjectiveOur objective was to examine the risk of type 2 diabetes mellitus (T2DM) in patients using antidepressants with and without M3 muscarinic receptor antagonism (AD_antaM3 and AD_nonantaM3, respectively).MethodsWe designed a case–control study using...

The influence of underweight and obesity on the diagnosis and treatment of appendicitis in children

Purpose The impact of lower body mass index (BMI) on appendicitis has never been addressed. We investigated whether different BMIs affect the diagnosis and treatment of appendicitis in children. Methods The correlation between BMI and diagnosis accuracy and treatment quality was evaluated by retrospective analysis of 457 children diagnosed with appendicitis. Based on BMI...

A delicate balance between rejection and BK polyomavirus associated nephropathy; A retrospective cohort study in renal transplant recipients

Background The immunosuppressive agents mycophenolate acid (MPA) and tacrolimus (Tac) are associated with a higher incidence of BK polyomavirus nephropathy (BKPyVAN). In this observational retrospective cohort study, the frequency of BK polyomavirus (BKPyV) complications over a 24-month period was studied. Methods 358 renal transplant recipients (RTR) treated with MPA, with...

Association between periconceptional weight loss and maternal and neonatal outcomes in obese infertile women

Oers, Meike A. Q. Mutsaerts, Henk Groen, Jolande A. Land, Walter K. Kuchenbecker, Ron van Golde, Gerrit J. E. Oosterhuis, Niels E. A. Vogel, Ben W. J. Mol, Annemieke Hoek, Jan M. Burggraaff, Denise A. M ... Greef. The lead author of the LIFEstyle study group is Annemieke Hoek, Author Contributions Conceptualization: Anne M. van Oers, Walter K. H. Kuchenbecker, Ben W. J. Mol, Henk Groen, Annemieke Hoek

Comparing the efficacy of a web-assisted calprotectin-based treatment algorithm (IBD-live) with usual practices in teenagers with inflammatory bowel disease: study protocol for a randomized controlled trial

Background To prevent clinical relapse in teenagers with inflammatory bowel disease (IBD) there is a need to monitor disease activity continuously. Timely optimisation of medical treatment may nip a preclinical relapse in the bud and change the natural course of IBD. Traditionally, disease monitoring is done during scheduled visits, but this is when most teenagers report full...

Effect of a lifestyle intervention in obese infertile women on cardiometabolic health and quality of life: A randomized controlled trial

Meike A. Q. Mutsaerts Rebecca C. Painter Aeilko H. Zwinderman Henk Groen 0 Cornelieke van de Beek Anneke C. Muller Kobold Walter K. H. Kuchenbecker Ron van Golde 1 Gerrit J. E. Oosterhuis Niels E. A ... . The following persons are members of the LIFEstyle study group: Anne M. van Oers, Meike A. Q. Mutsaerts, Henk Groen, Jolande A. Land, Walter K. Kuchenbecker, Ron van Golde, Gerrit J. E. Oosterhuis

Intestinal Fatty Acid-Binding Protein as a Diagnostic Marker for Complicated and Uncomplicated Necrotizing Enterocolitis: A Prospective Cohort Study

Background Early NEC symptoms are non-specific and diagnostic tests lack discriminative power. Intestinal fatty acid-binding protein (I-FABP), mainly located in small bowel enterocytes, is released into the blood following NEC-associated enterocyte disruption. Aim of this prospective cohort trial was to determine the diagnostic value of I-FABP measured in plasma (I-FABPp) and...

Modified natural cycle versus controlled ovarian hyperstimulation IVF: a cost-effectiveness evaluation of three simulated treatment scenarios

STUDY QUESTION Can modified natural cycle IVF or ICSI (MNC) be a cost-effective alternative for controlled ovarian hyperstimulation IVF or ICSI (COH)?

Economic Evaluation of a Problem Solving Intervention to Prevent Recurrent Sickness Absence in Workers with Common Mental Disorders

Groen 0 Jac J. L. van der Klink 0 Marianna Mazza, Catholic University of Sacred Heart of Rome, Italy 0 1 Department of Health Sciences, Community and Occupational Medicine, University Medical Center

Changes in Plasma Copeptin Levels during Hemodialysis: Are the Physiological Stimuli Active in Hemodialysis Patients?

Objectives Plasma levels of copeptin, a surrogate marker for the vasoconstrictor hormone arginine vasopressin (AVP), are increased in hemodialysis patients. Presently, it is unknown what drives copeptin levels in hemodialysis patients. We investigated whether the established physiological stimuli for copeptin release, i.e. plasma osmolality, blood volume and mean arterial...

P-Glycoprotein-Mediated Drug Interactions in Pregnancy and Changes in the Risk of Congenital Anomalies: A Case-Reference Study

, Groningen, The Netherlands. Conflict of interest Aizati Daud, Jorieke Bergman, Marian Bakker, Hao Wang, Wilhelmina Kerstjens-Frederikse, Hermien de Walle, Henk Groen, Jens Bos, Eelko Hak and Bob Wilffert

Vasopressin release is enhanced by the Hemocontrol biofeedback system and could contribute to better haemodynamic stability during haemodialysis

Background Haemodialysis with the Hemocontrol biofeedback system (HHD) is associated with improved haemodynamic stability compared with standard haemodialysis (HD) (SHD). Although the beneficial effect of HHD on haemodynamic stability is generally explained by its effect on blood volume, we questioned whether additional factors could play a role. Since HHD is associated with...

Elective laparoscopic recto-sigmoid resection for diverticular disease is suitable as a training operation

PurposeSome authors state that elective laparoscopic recto-sigmoid resection is more difficult for diverticular disease as compared with malignancy. For this reason, starting laparoscopic surgeons might avoid diverticulitis, making the implementation phase unnecessary long. The aim of this study was to determine whether laparoscopic resection for diverticular disease should be...

The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study

Introduction The aim of this study was to investigate the effect of three years of tumor necrosis factor-alpha (TNF-α) blocking therapy on bone turnover as well as to analyze the predictive value of early changes in bone turnover markers (BTM) for treatment discontinuation in patients with ankylosing spondylitis (AS). Methods This is a prospective cohort study of 111 consecutive...

The Impact of a Pulmonary-Artery-Catheter-Based Protocol on Fluid and Catecholamine Administration in Early Sepsis

A. Kuiper,1 Fellery de Lange,1,2 Paul Elbers,1 Henk Groen,3 Eric N. van Roon,4 and E. Christiaan Boerma1 1Department of Intensive Care, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden

The Impact of a Pulmonary-Artery-Catheter-Based Protocol on Fluid and Catecholamine Administration in Early Sepsis

A. Kuiper,1 Fellery de Lange,1,2 Paul Elbers,1 Henk Groen,3 Eric N. van Roon,4 and E. Christiaan Boerma1 1Department of Intensive Care, Medical Centre Leeuwarden, P.O. Box 888, 8901 BR Leeuwarden