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Search: authors:"Henryk Skarżyński"

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Reference values for psychoacoustic tests on Polish school children 7–10 years old

Background Good hearing is a fundamental skill that allows children to develop properly, both socially and intellectually. In contrast to defects in inner ear function, however, auditory processing disorders (APDs)–which can affect up to 2–3% of school-children–are not easily identified with basic screening programs and must be diagnosed using special tests. Although such...

Prevalence and severity of tinnitus in Polish otosclerosis patients qualified for stapes surgery

PurposeTo assess the prevalence and severity of tinnitus among a group of Polish patients with otosclerosis who qualified for stapes surgery. A secondary objective was to gauge the relationship between tinnitus severity and hearing thresholds.MethodsBased on the eligibility criteria, 460 adults with otosclerosis (236 women, 134 men) were included in the study. The Tinnitus...

Complications in septoplasty based on a large group of 5639 patients

PurposeSeptoplasty is a common surgical procedure used for correction of the nasal obstruction caused by a deviated septum. The aim of the study was to identify complications in septoplasty and analyze incidence depending on the surgical technique, based on the material from 2009 till 2017.MethodsThe material consisted of 5639 medical records from patients aged 16–69, operated in...

Chamber stapes prosthesis with an improved fastening of the membrane

Stapes prostheses are dedicated to assisting patients with otosclerosis. Currently used stapes prostheses have the form of a piston and are called piston prostheses. However, the perilymph excitation by piston prosthesis is not perfect so a new chamber stapes prosthesis (ChSP) has been proposed. The ChSP allows for a more effective stimulation of the cochlea than the piston. A...

Health-related quality of life and mental distress in patients with partial deafness: preliminary findings

The aim of the study was to evaluate mental distress and health-related quality of life in patients with bilateral partial deafness (high-frequency sensorineural hearing loss) before cochlear implantation, with respect to their audiological performance and time of onset of the hearing impairment. Thirty-one patients and 31 normal-hearing individuals were administered the Beck...

Slow Cortical Potential Neurofeedback in Chronic Tinnitus Therapy: A Case Report

This study is the first to demonstrate outcomes of slow cortical potential (SCP) Neurofeedback training in chronic tinnitus. A 50-year old male patient with tinnitus participated in three SCP training blocks, separated with 1-month breaks. After the training the patient reported decreased tinnitus loudness and pitch, as well as improved quality of daily life. A quantitative...

Novel and De Novo Mutations Extend Association of POU3F4 with Distinct Clinical and Radiological Phenotype of Hearing Loss

POU3F4 mutations (DFNX2) are the most prevalent among non-syndromic X-linked hearing loss (HL) identified to date. Clinical manifestations of DFNX2 usually comprise congenital HL either sensorineural or mixed, a tendency towards perilymphatic gusher during otologic surgery and temporal bone malformations. The aim of the present study was to screen for POU3F4 mutations in a group...

Reduced resting-state brain activity in the default mode network in children with (central) auditory processing disorders

Background In recent years, there has been a growing interest in Central Auditory Processing Disorder (C)APD. However, the neural correlates of (C)APD are poorly understood. Previous neuroimaging experiments have shown changes in the intrinsic activity of the brain in various cognitive deficits and brain disorders. The present study investigated the spontaneous brain activity in...

A modified oddball paradigm for investigation of neural correlates of attention: a simultaneous ERP–fMRI study

Introduction The objective of the presented study was to develop and evaluate a P300 experimental protocol for simultaneous registration of event-related potentials (ERPs) and functional MRI (fMRI) data with continuous imaging. It may be useful for investigating attention and working memory processes in specific populations, such as children and neuropsychiatric patients...

Postlingual Hearing Loss as a Mitochondrial 3243A>G Mutation Phenotype

Background The prevalence of isolated hearing loss (HL) associated with the m.3243A>G mutation is unknown. The aim of this study was to assess the frequency and heteroplasmy level of the m.3243A>G mutation in a large group of Polish patients with postlingual bilateral sensorineural HL of unidentified cause. Methodology/Principal Findings A molecular search was undertaken in the...