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Search: authors:"Hideaki Kouzaki"

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Human papillomavirus infection and immunohistochemical expression of cell cycle proteins pRb, p53, and p16 INK4a in sinonasal diseases

Background We aimed to clarify the possible role of human papillomavirus (HPV) infection in the malignant transformation of sinonasal inverted papilloma (IP). Methods Subjects comprised 32 patients with chronic rhinosinusitis (CRS), 17 with IP, 5 with IP and squamous cell carcinoma (IP + SCC), and 16 with primary sinonasal SCC. HPV presence, viral loads, and physical status were...