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A Study of Patients with Primary Mediastinal Germ Cell Tumors Treated Using Multimodal Therapy

Objectives. Primary mediastinal germ cell tumors (PMGCTs) are rare, which often makes them difficult to treat. Herein, we examined patients with PMGCTs who underwent multimodal treatment. Methods. We examined 6 patients (median age: 25 years, range: 19–27 years) with PMGCTs who underwent multimodal treatment between April 2001 and March 2015. Three patients had seminomas, 2...

Extramedullary plasmacytoma of the ureter in an HIV-positive patient

A 45-year-old Japanese man, who was undergoing HIV infection treatment, was aware that he had gross hematuria, and he was diagnosed as having a ureteral tumor by radiographic examination. Therefore, he was referred to our department for further examination and treatment. We considered that the ureteral tumor was a urothelial carcinoma (cT2N0M0) because of the left ureteral tumor...

Prophylactic effects of Bacille Calmette-Guérin intravesical instillation therapy: Time period-related comparison between Japan and Western countries

. Takehiko Okamura, Dr. Ryosuke Ando, Dr. Hidetoshi Akita, Dr. Noriyasu Kawai, Dr. Keiichi Tozawa, Dr. Kenjiro Kohri, and Dr. Hideo Arano reported no potential conflicts of interest relevant to this article

Neoadjuvant hormonal therapy is a feasible option in laparoscopic radical prostatectomy

Background Few reports can be found in the literature with respect to the impact of neoadjuvant hormonal therapy (NHT) on operative parameters on laparoscopic radical prostatectomy (LRP) in a large study. The aim of this study was to evaluate the safety and efficacy of NHT prior to LRP for locally confined prostate cancer. Methods From January 2004 to September 2009, 342 patients...

Cell cycle-dependent and ATM-independent expression of human Chk1 kinase

Kaneko, Hirobumi Morisaki, Hidetoshi Akita, Atsushi Fujimoto, Kaoru Tominaga, Motomu Terasawa, Kyoji Ikeda & Makoto NakanishiGene Bank, Tsukuba Life Science Center, RIKEN, 3-1-1 Koyadai, Tsukuba, Ibaraki ... Hidetoshi Akita in:Nature Research journals • PubMed • Google ScholarSearch for Atsushi Fujimoto in:Nature Research journals • PubMed • Google ScholarSearch for Kaoru Tominaga in:Nature Research journals