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10 papers found.
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Alteration in plasma free amino acid levels and its association with gout

Hiroki Amano Mikiko Kobayashi-Miura Hideyuki Kanda Yasuyuki Fujita Hiroshi Yamamoto Mai Yamamoto Shinya Kikuchi Atsuko Ikeda Naoko Kageyama Mina Nakamura Yasutaka Ishimaru 0 Hiroshi Sunagawa 0 Tsuyoshi

Plasma free amino acid profiles evaluate risk of metabolic syndrome, diabetes, dyslipidemia, and hypertension in a large Asian population

Background Recently, the association of plasma free amino acid (PFAA) profile and lifestyle-related diseases has been reported. However, few studies have been reported in large Asian populations, about the usefulness of PFAAs for evaluating disease risks. We examined the ability of PFAA profiles to evaluate lifestyle-related diseases in so far the largest Asian population...

Stratified phase II trial to establish the usefulness of the collagen gel droplet embedded culture-drug sensitivity test (CD-DST) for advanced gastric cancer

Background We conducted a multicenter phase II trial to assess the suitability of three types of chemotherapy (docetaxel plus S-1, irinotecan plus S-1, or S-1 alone) for patients with advanced gastric cancer by means of the collagen gel droplet embedded culture-drug sensitivity test (CD-DST). To our knowledge, this is the first multicenter clinical trial that has employed CD-DST...

Effects of hypoxia on coronary microcirculation during postnatal development

Fumio Yamamoto Hiroshi Yamamoto - Coronary microcirculation, functioning as an exchange system for solutes (e.g., oxygen, carbon dioxide, substrates, metabolites) between blood and tissues in the

Impact of FDG-PET findings on decisions regarding patient management strategies: a multicenter trial in patients with lung cancer and other types of cancer

Laboratory, Koyo Hospital. Hiroshi Yamamoto, Department of Radiology, Sumitomo Hospital Objective To date, numerous studies have been conducted on the diagnostic capabilities of positron emission tomography

Tumor-associated macrophages of the M2 phenotype contribute to progression in gastric cancer with peritoneal dissemination

Background Tumor-associated macrophages (TAMs) of the M2 phenotype are known to promote tumor proliferation and to be associated with a poor prognosis in numerous cancers. Here, we investigated whether M2 macrophages participate in the development of peritoneal dissemination in gastric cancer. Methods The characteristics of peritoneal macrophages in gastric cancer patients with...

Effect of inhibition of glycogen synthase kinase-3 on cardiac hypertrophy during acute pressure overload

Fumio Yamamoto Hiroshi Yamamoto Myocardial hypertrophy has been recognized to be an adaptive response to a variety of external stimuli (e.g., myocardial infarction, pressure overload, catecholamine

High preoperative neutrophil-lymphocyte ratio predicts poor survival in patients with gastric cancer

. - HIDEAKI SHIMADA, NOBUHIRO TAKIGUCHI, OSAMU KAINUMA, HIROAKI SODA, ATSUSHI IKEDA, AKIHIRO CHO, AKINARI MIYAZAKI, HISASHI GUNJI, HIROSHI YAMAMOTO, and MATSUO NAGATA Although preoperative tumor staging is