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Search: authors:"Hiroyuki Kondo"

3 papers found.
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Efficacy and safety of rotigotine in elderly patients with Parkinson’s disease in comparison with the non-elderly: a post hoc analysis of randomized, double-blind, placebo-controlled trials

Rotigotine—a non-ergot dopamine agonist—has two advantages; it can stimulate all dopamine receptors (D1–D5) like innate dopamine, and its transdermal administration provides continuous dopaminergic stimulation. The age of the patient impacts the effect and adverse events of anti-parkinsonian treatment. We conducted a post hoc analysis on three randomized, double-blind, placebo...

Effects of shocks, presented at a fixed time of day, on appetitive and general activity of rats

Eating, drinking, locomotion, and rearing activities of rats, maintained under a 12:12-h dark:light cycle, were measured continuously over 24 h a day for 40 days in the KGbox-24. For 20 days, beginning on Day 11, the shocks were given through the grid floor of the box 1 h after the beginning of the dark phase (at 2100 h). The daily food and water intake decreased, and there was...