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Efficacy of sirolimus for the prevention of recurrent pneumothorax in patients with lymphangioleiomyomatosis: a case series

Pneumothorax is one of the most common symptoms in patients with lymphangioleiomyomatosis (LAM). However, current management strategies for patients with LAM who present with recurrent pneumothorax remain inadequate. Here, we describe the successful prevention of recurrent pneumothorax by sirolimus treatment in five women with LAM. Before sirolimus treatment, all patients had...

Transdermal optical imaging revealed different spatiotemporal patterns of facial cardiovascular activities

Human cardiovascular activities are important indicators of a variety of physiological and psychological activities in human neuroscience research. The present proof-of-concept study aimed to reveal the spatiotemporal patterns of cardiovascular activities from the dynamic changes in hemoglobin concentrations in the face. We first recorded the dynamics of facial transdermal blood...

A warning for Chinese academic evaluation systems: short-term bibliometric measures misjudge the value of pioneering contributions

insightful perspectives coming from diverse stake holders. Compliance with ethics guidelines Xiao-jun HU, Jian-hong LUO, and Ronald ROUSSEAU declare that they have no conflict of interest. This article does

Hydrogen enhances strength and ductility of an equiatomic high-entropy alloy

-Planck-Institut für Eisenforschung, Max-Planck-Straße 1, Düsseldorf, 40237, GermanyHong Luo, Zhiming Li & Dierk Raabe AuthorsSearch for Hong Luo in:Nature Research journals • PubMed • Google Scholar

A multi-component discrete Boltzmann model for nonequilibrium reactive flows

We propose a multi-component discrete Boltzmann model (DBM) for premixed, nonpremixed, or partially premixed nonequilibrium reactive flows. This model is suitable for both subsonic and supersonic flows with or without chemical reaction and/or external force. A two-dimensional sixteen-velocity model is constructed for the DBM. In the hydrodynamic limit, the DBM recovers the...

Decitabine-Induced Changes in Human Myelodysplastic Syndrome Cell Line SKM-1 Are Mediated by FOXO3A Activation

The epigenetic silencing of tumor suppressor genes in myelodysplastic syndromes (MDS) can potentially confer a growth advantage to individual cellular clones. Currently, the recommended treatment for patients with high-risk MDS is the methylation agent decitabine (DAC), a drug that can induce the reexpression of silenced tumor suppressor genes. We investigated the effects of DAC...

Successful selective reduction of a heterotopic cesarean scar pregnancy in the second trimester: a case report and review of the literature

Background Heterotopic cesarean scar pregnancy is a cesarean scar pregnancy combined with an intrauterine pregnancy that predisposes a woman to life-threatening complications such as uterine rupture and massive bleeding. Preservation of the intrauterine pregnancy in heterotopic cesarean scar pregnancy is a great challenge. Case presentation We report a case of a 33-year-old woman...

An effective combination of whole-exome sequencing and runs of homozygosity for the diagnosis of primary ciliary dyskinesia in consanguineous families

-Mei Chen Dong-yuan Zheng Lv liu Xin-Gang Huang Ping Chen Hong Luo Yi-FengYang Published: xx xx xxxx Primary ciliary dyskinesia (PCD) is clinically characterized by neonatal respiratory distress ... assistance. This study was supported by the National Natural Science Foundation of China (81470202 to Hong Luo, 81470445 to Zhi-Ping Tan, 81570288 to Yi-Feng Yang), the Natural Science Foundation of Hunan

A versatile design for resonant guided-wave parametric down-conversion sources for quantum repeaters

Quantum repeaters—fundamental building blocks for long-distance quantum communication—are based on the interaction between photons and quantum memories. The photons must fulfil stringent requirements on central frequency, spectral bandwidth and purity in order for this interaction to be efficient. We present a design scheme for monolithically integrated resonant photon-pair...

Drimane Sesquiterpenoids and Isochromone Derivative from the Endophytic Fungus Pestalotiopsis sp. M-23

, 31570362), the Youth Innovation Promotion association of Chinese Academy of Sciences (awarded to Shi-Hong Luo), the ‘‘Western Light’’ Program of Chinese Academy of Sciences (awarded to Shi-Hong Luo), the

Understanding and identifying amino acid repeats

Hong Luo Harm Nijveen Amino acid repeats (AARs) are abundant in protein sequences. They have particular roles in protein function and evolution. Simple repeat patterns generated by DNA slippage tend

Association between tooth loss and risk of oesophageal cancer: a dose–response meta-analysis

Many epidemiological studies have found that tooth loss is associated with susceptibility to oesophageal cancer. However, a definitive answer is yet to be discovered, and the findings are inconclusive. We performed a meta-analysis to assess the relationship between tooth loss and oesophageal cancer risk. We searched PubMed and Embase databases to screen eligible studies up to...

Extrasynaptic NMDA receptor dependent long-term potentiation of hippocampal CA1 pyramidal neurons

. Author Contributions Sheng-Tian Li, and Jian-Hong Luo designed the experiments. Qian Yang, Jue-Gang Ju, Yue Zhang, Dandan Liu, Jiejie Wang and Weidong Li perfomed the experiments. Geng Zhu, Zhen-Hua Liao

Robust Linear Programming with Norm Uncertainty

March 2014; Accepted 28 April 2014; Published 11 May 2014 Academic Editor: Nan-Jing Huang Copyright © 2014 Lei Wang and Hong Luo. This is an open access article distributed under the Creative Commons

Pycnogenol attenuates atherosclerosis by regulating lipid metabolism through the TLR4–NF-κB pathway

Atherosclerosis is a leading cause of death worldwide and is characterized by lipid-laden foam cell formation. Recently, pycnogenol (PYC) has drawn much attention because of its prominent effect on cardiovascular disease (CVD). However, its protective effect against atherosclerosis and the underlying mechanism remains undefined. Here PYC treatment reduced areas of plaque and...

α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension

Wei Ma,2,5 Hong Luo,2 Guy Hughes,6 Zhaoyang Meng,1 Yi Yin,1 Yanling Wang,1 Junfa Li2 1Department of Ophthalmology, Beijing Friendship Hospital, 2Department of Neurobiology, Beijing Institute for Brain

Pharmacokinetically guided algorithm of 5-fluorouracil dosing, a reliable strategy of precision chemotherapy for solid tumors: a meta-analysis

Like Zhong Hong Luo Jingjing Li YunshanYang Ping Huang OPEN Precision medicine characterizes a new era of cancer care and provides each patient with the right drug at the right dose and time. However

Regularity of global solution to atmospheric circulation equations with humidity effect

equations with humidity effect Hong Luo 0 0 College of Mathematics and Software Science, Sichuan Normal University , Chengdu, Sichuan 610066 , China In this article, the regularity of the global solutions

Attractor bifurcation for the extended Fisher-Kolmogorov equation with periodic boundary condition

In this paper, we study the bifurcation and stability of solutions of the extended Fisher-Kolmogorov equation with periodic boundary condition. We prove that the system bifurcates from the trivial solution to an attractor as parameter crosses certain critical value. The topological structure of the attractor is also investigated.MSC: 35B32, 35K35, 37G35.

Steady State Solution to Atmospheric Circulation Equations with Humidity Effect

April 2012; Accepted 17 September 2012 Academic Editor: B. V. Rathish Kumar Copyright © 2012 Hong Luo. This is an open access article distributed under the Creative Commons Attribution License, which