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Evaluating the treatment effectiveness of copper-based algaecides on toxic algae Microcystis aeruginosa using single cell-inductively coupled plasma-mass spectrometry

Single cell-inductively coupled plasma-mass spectrometry (SC-ICP-MS) is an emerging technology. In this work, we have developed a novel SC-ICP-MS method to quantify metal ions in individual cells of a toxic cyanobacterial species, Microcystis aeruginosa (M. aeruginosa), without complicated post-dosing sample preparation, and applied this method to study the treatment...

Comparative efficacy of vasoactive medications in patients with septic shock: a network meta-analysis of randomized controlled trials

Catecholamines, especially norepinephrine, are the most frequently used vasopressors for treating patients with septic shock. During the recent decades, terlipressin, vasopressin V1A agonist, and even Ca2+ sensitizer were increasingly used by physicians. The aim of this study is to compare the efficacy of such different kinds of vasoactive medications on mortality among patients...

Growth suppression of colorectal cancer expressing S492R EGFR by monoclonal antibody CH12

Colorectal cancer (CRC) is a common malignant tumor in the digestive tract, and 30%–85% of CRCs express epidermal growth factor receptors (EGFRs). Recently, treatments using cetuximab, also named C225, an anti-EGFR monoclonal antibody, for CRC have been demonstrated to cause an S492R mutation in EGFR. However, little is known about the biological function of S492R EGFR. Therefore...

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells

The anticancer activity of genistein is increased in estrogen receptor beta 1-positive breast cancer cells Hua Jiang,1,* Jingjing Fan,2,* Lin Cheng,1 Pan Hu,1 Renbin Liu1 1Department of Breast and

Sialyltransferase ST3GAL1 promotes cell migration, invasion, and TGF-β1-induced EMT and confers paclitaxel resistance in ovarian cancer

Search for Congjian Xu in:Nature Research journals • PubMed • Google Scholar Search for Hua Jiang in:Nature Research journals • PubMed • Google Scholar Conflict of interest The authors declare that ... they have no conflict of interest. Corresponding author Correspondence to Hua Jiang. Rights and permissions Open Access This article is licensed under a Creative Commons Attribution 4.0

Giant spin-valley polarization and multiple Hall effect in functionalized bismuth monolayers

Jiayong Zhang in:Nature Research journals • PubMed • Google Scholar Search for Hua Jiang in:Nature Research journals • PubMed • Google Scholar Search for Igor Žutić in:Nature Research journals • PubMed

Novel preconditioning strategies for enhancing the migratory ability of mesenchymal stem cells in acute kidney injury

Acute kidney injury (AKI) remains a worldwide public health issue due to its increasing incidence, significant mortality, and lack of specific target-orientated therapy. Developments in mesenchymal stem cell (MSC) research make MSCs a promising candidate for AKI management but relevant clinical trials show confusing results (NCT00733876, NCT01602328). One primary cause of the...

Insecticidal Components from the Essential Oil of Chinese Medicinal Herb, Ligusticum chuanxiong Hort

Essential oil of Chinese medicinal herb, Ligusticum chuanxiong dried rhizome was found to possess insecticidal activity against maize weevils, Sitophilus zeamais. The main components of L. chuanxiong essential oil were Z-3-butylidenephthalide (20.56%), Z-ligustilide (19.61%), 4-terpinenol (8.82%), 4-vinylguaiacol (6.81%) and α-selinene (6.01%). Bioactivity-guided chromatographic...

Profiling circRNA and miRNA of radiation-induced esophageal injury in a rat model

. Qiang Zhan, Fangmei An and Wenyu Zhu contribute to acquire, analyze and interpret data. Hua Jiang and Changsheng Ma contribute to acquire data and enhance its intellectual content. All authors read and

Multiple molecular mechanisms form a positive feedback loop driving amyloid β42 peptide-induced neurotoxicity via activation of the TRPM2 channel in hippocampal neurons

neurons Xin Li 0 Lin-Hua Jiang 0 School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds , Leeds , UK 1 Sino-UK Joint Laboratory of Brain Function and Injury of Henan Province

An Adaptive Gradient Projection Algorithm for Piecewise Convex Optimization and Its Application in Compressed Spectrum Sensing

Signal sparse representation has attracted much attention in a wide range of application fields. A central aim of signal sparse representation is to find a sparse solution with the fewest nonzero entries from an underdetermined linear system, which leads to various optimization problems. In this paper, we propose an Adaptive Gradient Projection (AGP) algorithm to solve the...

SSAW: A new sequence similarity analysis method based on the stationary discrete wavelet transform

Alignment-free sequence similarity analysis methods often lead to significant savings in computational time over alignment-based counterparts. A new alignment-free sequence similarity analysis method, called SSAW is proposed. SSAW stands for Sequence Similarity Analysis using the Stationary Discrete Wavelet Transform (SDWT). It extracts k-mers from a sequence, then maps each k...

A multistage rotational speed changing molecular rotor regulated by pH and metal cations

21672026) and the 973 Program (2015CB856502). Author information AffiliationsCollege of Chemistry, Beijing Normal University, 100875, Beijing, ChinaYingying Wu, Guangxia Wang, Qiaolian Li, Hua Jiang ... Research journals • PubMed • Google Scholar Search for Hua Jiang in:Nature Research journals • PubMed • Google Scholar Search for Ying Wang in:Nature Research journals • PubMed • Google Scholar

Collaborative representation-based classification of microarray gene expression data

(Grant No. 17KJB510024) Author Contributions Conceptualization: Hua Jiang. Data curation: Lizhen Shen, Hua Jiang. Formal analysis: Lizhen Shen, Mingfang He, Guoqing Liu. Funding acquisition: Mingfang ... He, Guoqing Liu. Investigation: Lizhen Shen. Methodology: Lizhen Shen, Mingfang He. Project administration: Lizhen Shen, Hua Jiang. Resources: Lizhen Shen, Hua Jiang. Software: Lizhen Shen, Guoqing

Role of Cholinergic Anti-Inflammatory Pathway in Treatment of Intestinal Ischemia-Reperfusion Injury by Electroacupuncture at Zusanli

Electroacupuncture (EA) at Zusanli is a widely used method for the treatment of intestinal ischemic disease. The current study attempts to investigate the possible mechanism from the point of cholinergic anti-inflammatory pathway (CAP) in rats. Thirty rats were divided into five groups: control group, I/R group, EA group (I/R

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms

Jenaro Garcia-Huidobro in:Nature Research journals • PubMed • Google Scholar Search for Hua Jiang in:Nature Research journals • PubMed • Google Scholar Search for Antonio Colaprico in:Nature Research

Detection of pathogenic microorganisms from bloodstream infection specimens using TaqMan array card technology

Bloodstream infections (BSIs) are often life-threatening, and rapid identification is critical. Here, we developed a TaqMan array card (TAC) assay to detect pathogens in BSI specimens. The TAC included 30 primer/probe pairs targeting 27 species and 3 controls. Reverse transcription and 0.1% blue dextran 2000 increased the TAC assay efficiency. The primer/probe pairs had a limit...

A web-based GPS system for displacement monitoring and failure mechanism analysis of reservoir landslide

, 330000, ChinaJinsong Huang, Shui-Hua Jiang, Faming Huang & Zhilu ChangARC Centre of Excellence for Geotechnical Science and Engineering, University of Newcastle, NSW, AustraliaJinsong Huang AuthorsSearch ... for Yuanyao Li in:Nature Research journals • PubMed • Google Scholar Search for Jinsong Huang in:Nature Research journals • PubMed • Google Scholar Search for Shui-Hua Jiang in:Nature Research