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Comprehensive analysis of competitive endogenous RNAs network associated with head and neck squamous cell carcinoma

Long non-coding RNAs (lncRNAs) can regulate gene expression directly or indirectly through interacting with microRNAs (miRNAs). However, the role of differentially expressed mRNAs, lncRNAs and miRNAs, and especially their related competitive endogenous RNAs (ceRNA) network in head and neck squamous cell carcinoma (HNSCC), is not fully comprehended. In this paper, the lncRNA...

The prospect of rising in rank is key to long-term stability in Tibetan macaque society

One of the most fundamental questions in behavioural biology is why societies can persist for a long period of time. While researchers in animal behaviour have been hindered by a lack of an aggregate measure (such as social mobility) to quantify the dynamics of animal societies, researchers in social sciences have been challenged by the complexity and diversity of human societies...

Baculovirus-Mediated miR-214 Knockdown Shifts Osteoporotic ASCs Differentiation and Improves Osteoporotic Bone Defects Repair

. AffiliationsDepartment of Chemical Engineering, National Tsing Hua University, Hsinchu, 300, TaiwanKuei-Chang Li, Mu-Nung Hsu, Shih-Chun Lo, Wan-Hua Li & Yu-Chen HuCenter for Tissue Engineering, Chang Gung Memorial ... Research journals • PubMed • Google Scholar Search for Wan-Hua Li in:Nature Research journals • PubMed • Google Scholar Search for Yu-Chen Hu in:Nature Research journals • PubMed • Google Scholar

Ecophysiological response of native and exotic salt marsh vegetation to waterlogging and salinity: Implications for the effects of sea-level rise

The ecophysiological characteristics of native Phragmites australis and exotic Spartina alterniflora grown under waterlogging and salinity were investigated to explore their adaptation potential to sea level rise. The seasonal course of phenotypic traits, photosynthetic activity and chlorophyll fluorescence parameters of P. australis did not change remarkably under shallow...

MiR-200c regulates tumor growth and chemosensitivity to cisplatin in osteosarcoma by targeting AKT2

to this work. AffiliationsDepartment of Orthopedic, Huaihe Hospital of Henan University, Baobei Road 8, 475000, Kaifeng, Henan, ChinaYang Liu, Shu-Tao Zhu, Xiao Wang, Jun Deng, Wei-Hua Li, Peng Zhang ... in:Nature Research journals • PubMed • Google Scholar Search for Jun Deng in:Nature Research journals • PubMed • Google Scholar Search for Wei-Hua Li in:Nature Research journals • PubMed • Google Scholar

Utility of quantitative contrast-enhanced ultrasound for the prediction of extracapsular extension in papillary thyroid carcinoma

-Hua Li OPEN Published: xx xx xxxx The aim of this study was to find an accurate method for the detection of extracapsular extension (ECE) in papillary thyroid carcinoma (PTC). A total of 102 patients

Anisomycin prevents OGD-induced necroptosis by regulating the E3 ligase CHIP

Necroptosis is an essential pathophysiological process in cerebral ischemia-related diseases. Therefore, targeting necroptosis may prevent cell death and provide a much-needed therapy. Ansiomycin is an inhibitor of protein synthesis which can also activate c-Jun N-terminal kinases. The present study demonstrated that anisomycin attenuated necroptosis by upregulating CHIP...

Bio-Engineered Graphene-Based Cage for Efficient Local Enrichment and Biodegradation of Aqueous Organic Wastes

Microorganism immobilization has attracted great attention as a traditional method to overcome aqueous organic wastes containing N, N-dimethylformamide (DMF). In this approach, graphene oxide was modified with functional polymer firstly to obtain micro-composites material (PGO), and then the prepared composites were deposited on the surface of copper mesh (CM) to block the meshes...

Association of TNFSF4 Polymorphisms with Vogt-Koyanagi-Harada and Behcet’s Disease in Han Chinese

To investigate whether single nucleotide polymorphisms (SNPs) of the Tumor Necrosis Factor Superfamily 4 (TNFSF4) gene are associated with Vogt–Koyanagi–Harada (VKH) and Behcet’s disease (BD) in a Chinese Han population. A two-stage case control study was carried out in 1331 VKH, 938 BD and 1752 healthy controls. Ten TNFSF4 SNPs, including rs1234314, rs1234315, rs2205960...

Association between LRP1 C766T polymorphism and Alzheimer’s disease susceptibility: a meta-analysis

Low density lipoprotein receptor-related protein 1 (LRP1) C766T polymorphism (rs1799986) has been extensively investigated for Alzheimer’s disease (AD) susceptibility. However, results in different studies have been contradictory. Therefore, we conducted a meta-analysis containing 6455 AD cases and 6304 controls from 26 independent case–control studies to determine whether there...

A Simple Paper-Based Colorimetric Device for Rapid Mercury(II) Assay

200433, P.R. ChinaWeiwei Chen, Xueen Fang, Hua Li, Hongmei Cao & Jilie Kong AuthorsSearch for Weiwei Chen in:Nature Research journals • PubMed • Google ScholarSearch for Xueen Fang in:Nature Research ... journals • PubMed • Google ScholarSearch for Hua Li in:Nature Research journals • PubMed • Google ScholarSearch for Hongmei Cao in:Nature Research journals • PubMed • Google ScholarSearch for Jilie Kong

Lymph node ratio is associated with adverse clinicopathological features and is a crucial nodal parameter for oral and oropharyngeal cancer

, Chong Wang, Jin Zhong Li, Ming Hui Mao, Hua Li, Li Zheng Qin & Zhengxue Han AuthorsSearch for Zhien Feng in:Nature Research journals • PubMed • Google Scholar Search for Qiao Shi Xu in:Nature Research ... Hui Mao in:Nature Research journals • PubMed • Google Scholar Search for Hua Li in:Nature Research journals • PubMed • Google Scholar Search for Li Zheng Qin in:Nature Research journals • PubMed

Gas Protection of Two-Dimensional Nanomaterials from High-Energy Impacts

Two-dimensional (2D) materials can be produced using ball milling with the help of liquid surfactants or solid exfoliation agents, as ball milling of bulk precursor materials usually produces nanosized particles because of high-energy impacts. Post-milling treatment is thus needed to purify the nanosheets. We show here that nanosheets of graphene, BN, and MoS2 can be produced by...

An expression based REST signature predicts patient survival and therapeutic response for glioblastoma multiforme

Xiaodong Zhao 3 Hua Li 3 0 Peking University China-Japan Friendship School of Clinical Medicine , Beijing, 100029 , China 1 Department of Nutrition, Jinan Central Hospital Affiliated to Shandong University

The identification and molecular mechanism of anti-stroke traditional Chinese medicinal compounds

Stroke is a worldwide epidemic disease with high morbidity and mortality. The continuously exploration of anti-stroke medicines and molecular mechanism has a long way to go. In this study, in order to screen candidate anti-stroke compounds, more than 60000 compounds from traditional Chinese medicine (TCM) database were computationally analyzed then docked to the 15 known anti...

Fabrication of Unique Magnetic Bionanocomposite for Highly Efficient Removal of Hexavalent Chromium from Water

Biotreatment of hexavalent chromium has attracted widespread interest due to its cost effective and environmental friendliness. However, the difficult separation of biomass from aqueous solution and the slow hexavalent chromium bioreduction rate are bottlenecks for biotechnology application. In this approach, a core-shell structured functional polymer coated magnetic...

6.2-GHz modulated terahertz light detection using fast terahertz quantum well photodetectors

The fast detection of terahertz radiation is of great importance for various applications such as fast imaging, high speed communications, and spectroscopy. Most commercial products capable of sensitively responding the terahertz radiation are thermal detectors, i.e., pyroelectric sensors and bolometers. This class of terahertz detectors is normally characterized by low...

Silencing salusin-β attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats

Zhou, Ying Han, Ye-Bo Zhou & Guo-Qing ZhuDepartment of Pathophysiology, Nanjing Medical University, Nanjing, Jiangsu 211166, ChinaQi Chen, Yue-Hua Li & Guo-Qing ZhuDepartment of Physiology and ... • Google ScholarSearch for Ye-Bo Zhou in:Nature Research journals • PubMed • Google ScholarSearch for Qi Chen in:Nature Research journals • PubMed • Google ScholarSearch for Yue-Hua Li in:Nature Research

Magnesium alloy covered stent for treatment of a lateral aneurysm model in rabbit common carotid artery: An in vivo study

• Google ScholarSearch for Yong-Dong Li in:Nature Research journals • PubMed • Google ScholarSearch for Ming-Hua Li in:Nature Research journals • PubMed • Google ScholarSearch for Guang-Yin Yuan in:Nature ... Correspondence to Yong-Dong Li or Ming-Hua Li or Guang-Yin Yuan. Rights and permissions This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party

Neurotoxicity Comparison of Two Types of Local Anaesthetics: Amide-Bupivacaine versus Ester-Procaine

Local anaesthetics (LAs) may lead to neurological complications, but the underlying mechanism is still unclear. Many neurotoxicity research studies have examined different LAs, but none have comprehensively explored the distinct mechanisms of neurotoxicity caused by amide- (bupivacaine) and ester- (procaine) type LAs. Here, based on a CCK8 assay, LDH assay, Rhod-2-AM and JC-1...