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102 papers found.
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Impact of various types of near work and time spent outdoors at different times of day on visual acuity and refractive error among Chinese school-going children

Boswell, Yaojiang Shi, Scott Rozelle, Nathan Congdon. Methodology: Huan Wang, Scott Rozelle, Nathan Congdon. Project administration: Hongyu Guan, Huan Wang, Matthew Boswell. Resources: Matthew Boswell ... , Scott Rozelle. Supervision: Yaojiang Shi. Writing ? original draft: Hongyu Guan, Ning Neil Yu. Writing ? review & editing: Hongyu Guan, Huan Wang, Matthew Boswell, Nathan Congdon. 11 / 13 12 / 13 1

Dinitroimidazoles as bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization

Efficient and site-specific chemical modification of proteins under physiological conditions remains a challenge. Here we report that 1,4-dinitroimidazoles are highly efficient bifunctional bioconjugation reagents for protein functionalization and peptide macrocyclization. Under acidic to neutral aqueous conditions, 1,4-dinitroimidazoles react specifically with cysteines via a...

Feasibility study on color evaluation of jadeite based on GemDialogue color chip images

Through the calculation of gemological chromaticity, the green characters and range of chromaticity of 728 cabochon jadeite jade were determined, and then it studies and compares with GemDialogue color card images for jadeite-jade green quality evaluation. It is testified that the method is proved to be effective and the construction of emerald green quality grading system based...

Emerging barcode particles for multiplex bioassays

With the increasing demand for multiplex and high-throughput analysis of large numbers of biomolecules, multiplex technology becomes a promising tool for carrying out thousands of individual reactions at the same time for large-scale biological analysis. Among current technologies, suspension arrays based on appropriate barcode particles have been popularly used in multiplex...

A time series of urban extent in China using DSMP/OLS nighttime light data

S1 File. The time series of urban extent in China underlying the findings described in manuscript. (ZIP) (ZIP) S2 File. The raw files of all figures contained in manuscript. Data curation: Huan Wang

Efficacy of Brucea javanica Oil Emulsion Injection Combined with the Chemotherapy for Treating Gastric Cancer: A Systematic Review and Meta-Analysis

, and Kai-Huan Wang Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China Correspondence should be addressed to Jia-Rui

Efficacy of Brucea javanica Oil Emulsion Injection Combined with the Chemotherapy for Treating Gastric Cancer: A Systematic Review and Meta-Analysis

, and Kai-Huan Wang Department of Clinical Chinese Pharmacy, School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing 100102, China Correspondence should be addressed to Jia-Rui

The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70

Epstein–Barr virus (EBV) can infect cells in latent and lytic period and cause serious disease. Epstein–Barr virus nuclear antigen 1 (EBNA1) is essential for the maintenance of the EBV DNA episome, replication and transcription. 2-phenylethynesulfonamide (PES) is a small molecular inhibitor of Heat shock protein 70 (Hsp70), which can interact with Hsp70 and disrupts its...

Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China

Background and Aims. We want to investigate whether a novel noninvasive marker is suitable for Chinese CHB patients. Methods. A total of 160 treatment-naïve CHB patients who underwent liver biopsy were enrolled in our study, and we assessed the diagnostic accuracies of GPR, aspartate transaminase-to-platelet ratio index (APRI), and the fibrosis index based on 4 factors (FIB-4) in...

Gamma-Glutamyl Transpeptidase-to-Platelet Ratio Predicts Significant Liver Fibrosis of Chronic Hepatitis B Patients in China

Background and Aims. We want to investigate whether a novel noninvasive marker is suitable for Chinese CHB patients. Methods. A total of 160 treatment-naïve CHB patients who underwent liver biopsy were enrolled in our study, and we assessed the diagnostic accuracies of GPR, aspartate transaminase-to-platelet ratio index (APRI), and the fibrosis index based on 4 factors (FIB-4) in...

Impact of family integrated care on infants’ clinical outcomes in two children’s hospitals in China: a pre-post intervention study

Most Neonatal Intensive Care Units (NICUs) in China have restricted visiting policies for parents. This also implicates that parents are not involved in the care of their infant. Family Integrated Care (FIC), empowering parents in direct care delivery and decisions, is becoming the standard in NICUs in many countries and can improve quality-of-life and health outcomes of preterm...

Fingolimod suppresses neuronal autophagy through the mTOR/p70S6K pathway and alleviates ischemic brain damage in mice

Li, Ming-Huan Wang. Formal analysis: Chuan Qin. Funding acquisition: Dai-Shi Tian, Jun-Li Liu. Investigation: Chuan Qin, Wen-Hui Fan. Methodology: Ming-Huan Wang, Chuan Qin, Wen-Hui Fan. Project ... administration: Dai-Shi Tian, Jun-Li Liu. Software: Chuan Qin. Supervision: Jun-Li Liu. Validation: Chuan Qin, Wen-Hui Fan. Visualization: Wen-Hui Fan. Writing ± original draft: Xiao Li, Ming-Huan Wang

The persistence and performance of phosphate-solubilizing Gluconacetobacter liquefaciens qzr14 in a cucumber soil

The persistence and performance of plant growth-promoting microorganisms (PGPMs) in soil are considered critical features for effectiveness, yet they are poorly understood. Here, we investigated the colonization and activity of a new PGPM, phosphate-solubilizing Gluconacetobacter liquefaciens qzr14, in a pot culture experiment using cucumber as test crop for 20 days. The number...

A robust estimator of parameters for \( {\mathcal{G}}_I^0 \) -modeled SAR imagery based on random weighting method

perform the analysis with constructive discussions and revised the manuscript; X-BW and H-XX approved the final version. All authors read and approved the final manuscript. Authors’ information Cui-Huan ... Wang received the B.S. degree in Communication Engineering from North College of Beijing University of Chemical Technology, Hebei, China, in 2014. Currently, she is pursuing her master’s degree in

Selection and evaluation of new reference genes for RT-qPCR analysis in Epinephelus akaara based on transcriptome data

Groupers are an economically important fish species in world fishery markets. Because many studies using RT-qPCR have addressed gene expression in groupers, appropriate reference genes are required to obtain reliable and accurate results. In this study, the most suitable reference genes were identified from eleven candidate genes of one of the most valuable species, Epinephelus...

Melting of Pb Nanocrystals Embedded in Al, Si, and Cu Matrices

Dispersions of nanoscale Pb particles embedded in Si, Al, and Cu matrices have been synthesized by ion implantation and subsequent annealing. The melting transitions of the embedded Pb nanocrystals with epitaxial particle/matrix interfaces were investigated by means of in situ high-temperature X-ray diffraction. Due to different levels of lattice mismatch, the Pb nanoprecipitates...

ClC-3 chloride channel mediates the role of parathyroid hormone [1-34] on osteogenic differentiation of osteoblasts

Introduction Different concentrations of parathyroid hormone [1–34] (PTH [1–34]) can have totally opposite effects on osteoblasts. Intermittent stimulation with PTH can significantly increase bone mineral density in vitro, mainly through the protein kinase A (PKA) signaling pathway, which phosphorylates runt-related transcription factor 2 (Runx2). The ClC-3 chloride channel, an...