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Brain protection against ischemic stroke using choline as a new molecular bypass treatment

, analyzed the data, and wrote the manuscript; Ru-huan WANG conducted some of the experiments; and Chao-liang LONG and Hui WANG participated in discussions and writing the manuscript. Abbreviations nAChR

Inhibitory effects of hesperetin on Nav1.5 channels stably expressed in HEK 293 cells and on the voltage-gated cardiac sodium current in human atrial myocytes

, and Xin-ling DU designed the study; Huan WANG, Hao ZHANG, Chen WANG, and Yu-fang CHEN performed the experiments; Huan WANG and Rong MA analyzed the data; Hong-fei WANG, Chen WANG, and Yu-fang CHEN ... provided the reagents and materials; and Huan WANG, Hong-fei WANG, and Qiang TANG wrote the paper. References 1. Kleber AG, Rudy Y. Basic mechanisms of cardiac impulse propagation and associated

The novel ATP-sensitive potassium channel opener iptakalim prevents insulin resistance associated with hypertension via restoring endothelial function

Aim:To investigate the effects of iptakalim on endothelial dysfunction induced by insulin resistance (IR) and to determine whether iptakalim improved IR associated with hypertension in fructose-fed rats (FFRs) and spontaneously hypertensive rats (SHRs).Methods:Human umbilical vein endothelial cells (HUVECs) were used for in vitro study. The levels of endothelial vasoactive...