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The Hsp70 inhibitor 2-phenylethynesulfonamide inhibits replication and carcinogenicity of Epstein–Barr virus by inhibiting the molecular chaperone function of Hsp70

Epstein–Barr virus (EBV) can infect cells in latent and lytic period and cause serious disease. Epstein–Barr virus nuclear antigen 1 (EBNA1) is essential for the maintenance of the EBV DNA episome, replication and transcription. 2-phenylethynesulfonamide (PES) is a small molecular inhibitor of Heat shock protein 70 (Hsp70), which can interact with Hsp70 and disrupts its...

MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A

People’s Hospital, Tangshan, 063000, ChinaMeiyue Liu, Chao Zhang, Zhao Yang, Yi Niu, Huan Wang, Xiaomei Wei, Wei Wang, Peng Gao & Guogui SunDepartment of Nuclear Medicine, The Second Hospital of Tianjin ... • Google Scholar Search for Yi Niu in:Nature Research journals • PubMed • Google Scholar Search for Huan Wang in:Nature Research journals • PubMed • Google Scholar Search for Xiaomei Wei in:Nature Research