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Existence of Two Positive Periodic Solutions for a Neutral Multi-Delay Logarithmic Population Model with a Periodic Harvesting Rate

and Technology, Yunnan 650500, China Received 14 July 2012; Accepted 12 November 2012 Academic Editor: Wing-Sum Cheung Copyright © 2012 Hui Fang. This is an open access article distributed under

Existence of Two Positive Periodic Solutions for a Neutral Multi-Delay Logarithmic Population Model with a Periodic Harvesting Rate

and Technology, Yunnan 650500, China Received 14 July 2012; Accepted 12 November 2012 Academic Editor: Wing-Sum Cheung Copyright © 2012 Hui Fang. This is an open access article distributed under

Salvianolic acid A attenuates vascular remodeling in a pulmonary arterial hypertension rat model

Aim:The current therapeutic approaches have a limited effect on the dysregulated pulmonary vascular remodeling, which is characteristic of pulmonary arterial hypertension (PAH). In this study we examined whether salvianolic acid A (SAA) extracted from the traditional Chinese medicine 'Dan Shen' attenuated vascular remodeling in a PAH rat model, and elucidated the underlying...

Metabolic and pharmacokinetic studies of scutellarin in rat plasma, urine, and feces

in enzyme activity. Author contribution Jian-feng XING and Ya-lin DONG designed the study, performed the research and wrote the paper. Hai-sheng YOU, Jun LU, Si-ying CHEN, Hui-fang ZHU, Qian DONG ... , the First Affiliated Hospital, Medical College, Xi-an Jiaotong University, Xi-an 710061, ChinaHai-sheng You, Ya-lin Dong, Jun Lu, Si-ying Chen, Hui-fang Zhu, Qian Dong, Mao-yi Wang & Wei-hua Dong

Addictive evaluation of cholic acid-verticinone ester, a potential cough therapeutic agent with agonist action of opioid receptor

designed research; Hui WANG and Chang CHEN performed research; Hui-fang PI, Han-li RUAN, Peng ZHANG and Ji-zhou WU contributed analytical tools and analytical support; Jiu-liang ZHANG wrote the paper ... Laboratory of Natural Medicinal Chemistry and Resource Evaluation, Tongji School of Pharmacy, Huazhong University of Science and Technology, Wuhan 430030, ChinaJiu-liang Zhang, Hui Wang, Chang Chen, Hui-fang

Quantitative determination of acetylshikonin in macaque monkey blood by LC-ESI-MS/MS after precolumn derivatization with 2-mercaptoethanol and its application in pharmacokinetic study

-xiao SUN, Zhi-yun MENG, and Gui-fang DOU designed research; Dong-xiao SUN and Hui-fang TIAN performed research; Alicia DU, Zhuo-na WU contributed new analytical tools and reagents; Dong-xiao SUN, Zhiyun

Synthesis and antitussive evaluation of verticinone-cholic acid salt, a novel and potential cough therapeutic agent

Aim:To seek a novel and potent antitussive drug based on Shedan—Chuanbei powder, a complex of traditional Chinese medicine preparation for cough therapy.Methods:Verticinone—cholic acid (Ver—CA) salt, a novel, salifying derivative of verticinone and cholic acid, both of which are the major bioactive components in Shedan—Chuanbei powder, was synthesized. We then evaluated the...

Chaos in a single-species discrete population model with stage structure and birth pulses

This paper gives an analytical proof of the existence of chaotic dynamics for a single-species discrete population model with stage structure and birth pulses. The approach is based on a general existence criterion for chaotic dynamics of n-dimensional maps and inequality techniques. An example is given to illustrate the effectiveness of the result.

Four periodic solutions for a food-limited two-species Gilpin-Ayala type predator-prey system with harvesting terms on time scales

By using Mawhin’s coincidence degree theory, this paper establishes a new criterion on the existence of four periodic solutions for a food-limited two-species Gilpin-Ayala type predator-prey system with harvesting terms on time scales. An example is given to illustrate the effectiveness of the result.

Existence of Weak Solutions for Second-Order Boundary Value Problem of Impulsive Dynamic Equations on Time Scales

Fang 0 Recommended by Victoria Otero-Espinar 0 Department of Applied Mathematics, Kunming University of Science and Technology , Kunming, Yunnan 650093 , China We study the existence of weak solutions

Existence of Periodic and Subharmonic Solutions for Second-Order p-Laplacian Difference Equations

We obtain a sufficient condition for the existence of periodic and subharmonic solutions of second-order p-Laplacian difference equations using the critical point theory.

Multiple periodic solutions for a discrete time model of plankton allelopathy

We study a discrete time model of the growth of two species of plankton with competitive and allelopathic effects on each other N1(k+1) = N1(k)exp{r1(k)-a11(k)N1(k)-a12(k)N2(k)-b1(k)N1(k)N2(k)}, N2(k+1) = N2(k)exp{r2(k)-a21(k)N2(k)-b2(k)N1(k)N1(k)N2(k)}. A set of sufficient conditions is obtained for the existence of multiple positive periodic solutions for this model. The...

Treatment adherence among sputum smear-positive pulmonary tuberculosis patients in mountainous areas in China

Background We carried out an investigation in five provinces in China to assess treatment adherence and identify factors associated with insufficient treatment adherence in tuberculosis (TB) patients in mountainous, rural areas of China. Methods In each of the five provinces, all counties with > 80% mountainous area were stratified into three groups according to their gross...

Molecular characterization of the piggyBac-like element, a candidate marker for phylogenetic research of Chilo suppressalis (Walker) in China

Background Transposable elements (TEs, transposons) are mobile genetic DNA sequences. TEs can insert copies of themselves into new genomic locations and they have the capacity to multiply. Therefore, TEs have been crucial in the shaping of hosts’ current genomes. TEs can be utilized as genetic markers to study population genetic diversity. The rice stem borer Chilo suppressalis...

Compensatory patterns of collateral flow in stroke patients with unilateral and bilateral carotid stenosis

Background Collateral pathways are important in maintaining adequate cerebral blood flow in patients with carotid stenosis. We aimed to evaluate the hemodynamic patterns in relation to carotid stenosis in acute stroke patients. Methods Consecutive 586 stroke patients in a hospital based cohort were included in the present study. Carotid duplex was performed to identify patients...

Assessment of a multiple biomarker panel for diagnosis of amyotrophic lateral sclerosis

Background The aim of the study was to assess a panel of promising biomarkers for their ability to improve diagnosis of sporadic amyotrophic lateral sclerosis (ALS). Methods Forty patients with sporadic ALS and 40 controls with other neurological diseases were evaluated. Levels of phosphorylated neurofilament heavy chain (pNfH), S100-β, cystatin C, and chitotriosidase (CHIT) in...

Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats

Nonalcoholic steatohepatitis (NASH) is characterized by fat accumulation in the hepatocyte, inflammation, liver cell injury, and varying degrees of fibrosis, and can lead to oxidative stress in liver. Here, we investigated whether Salidroside, a natural phenolic antioxidant product, can protect rat from liver injury during NASH. NASH model was established by feeding the male SD...

Salidroside alleviates oxidative stress in the liver with non- alcoholic steatohepatitis in rats

Background Nonalcoholic steatohepatitis (NASH) is characterized by fat accumulation in the hepatocyte, inflammation, liver cell injury, and varying degrees of fibrosis, and can lead to oxidative stress in liver. Here, we investigated whether Salidroside, a natural phenolic antioxidant product, can protect rat from liver injury during NASH. Methods NASH model was established by...

Estimation of the benchmark dose of urinary cadmium as the reference level for renal dysfunction: a large sample study in five cadmium polluted areas in China

Background Itai-itai disease primarily results from cadmium (Cd) exposure and is known as one of the four major pollution diseases in Japan. Cd pollution is more serious in several areas of China than in Japan. However, there is still a lack of information regarding the threshold level of Cd exposure for the adverse health effects in the general Chinese population. This study...

Resiquimod and polyinosinic–polycytidylic acid formulation with aluminum hydroxide as an adjuvant for foot-and-mouth disease vaccine

Background Toll-like receptor (TLR) agonists reportedly have potent antiviral and antitumor activities and may be a new kind of adjuvant for enhancing immune efficacy. Resiquimod (R848) is an imidazoquinoline compound with potent antiviral activity and functions through the TLR7/TLR8 MyD88-dependent signaling pathway. Polyinosinic-polycytidylic acid [poly(I:C)] is a synthetic...