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A germline mutation in Rab43 gene identified from a cancer family predisposes to a hereditary liver-colon cancer syndrome

Hereditary cancer syndromes have inherited germline mutations which predispose to benign and malignant tumors. Understanding of the molecular causes in hereditary cancer syndromes has advanced cancer treatment and prevention. However, the causal genes of many hereditary cancer syndromes remain unknown due to their rare frequency of mutation. A large Chinese family with a history...

Multiple Kernel Dimensionality Reduction via Ratio-Trace and Marginal Fisher Analysis

; Published 14 January 2019 Academic Editor: Ezequiel López-Rubio Copyright © 2019 Hui Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits

Ehrlichia species in pond-farmed leeches (Hirudinaria sp.) in Hubei Province, China

Zhang, Wen-Liang Lv. Formal analysis: Shu-Han Zhou, Xiao Xiao, Qing-Hua Gao. Funding acquisition: Wen-Liang Lv, Qing-Hua Gao. 9 / 11 Investigation: Shu-Han Zhou, Yi-Na Sun, Xiao-Hui Xu, Xin Ding, Si-Yi ... Zhang, Min Zhang. Project administration: Wen-Liang Lv. Resources: Shu-Han Zhou, Yi-Na Sun, Si-Yi Zhang, Qing-Hua Gao. Software: Xiao Xiao, Xiao-Hui Xu. Writing ? original draft: Xiao Xiao. Writing

MTMR2 promotes invasion and metastasis of gastric cancer via inactivating IFNγ/STAT1 signaling

The aberrant expression of myotubularin-related protein 2 (MTMR2) has been found in some cancers, but little is known about the roles and clinical relevance. The present study aimed to investigate the roles and clinical relevance of MTMR2 as well as the underlying mechanisms in gastric cancer (GC). MTMR2 expression was examined in 295 GC samples by using immunohistochemistry (IHC...

Satellite Soil Moisture and Its Applications

that they have no conflicts of interest. Jifu Yin Runping Shen Qingyan Meng Hui Xu Heshun Wang

On a New Subclass of -Valent Close-to-Convex Mappings Defined by Two-Sided Inequality

Editor: Henryk Hudzik Copyright © 2018 Yi-Hui Xu and Jin-Lin Liu. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution

Preparation of Hollow Polyaniline Micro/Nanospheres and Their Removal Capacity of Cr (VI) from Wastewater

The hollow polyaniline (PANI) micro/nanospheres are obtained through a simple monomer polymerization in alkaline solution with Triton X-100 Micelles as soft templates. The hollow PANI micro/nanospheres demonstrate rapid and effective removal ability for Chromium (VI) (Cr (VI)) in a wide pH range, and the maximum removal capacity can reach 127.88 mg/g at pH 3. After treated with...

Systematic identification of the key candidate genes in breast cancer stroma

BackgroundTumor microenvironment, in particular the stroma, plays an important role in breast cancer cell invasion and metastasis. Investigation of the molecular characteristics of breast cancer stroma may reveal targets for future study.MethodsThe transcriptome profiles of breast cancer stroma and normal breast stroma were compared to identify differentially expressed genes...

Systematic identification of the key candidate genes in breast cancer stroma

Tumor microenvironment, in particular the stroma, plays an important role in breast cancer cell invasion and metastasis. Investigation of the molecular characteristics of breast cancer stroma may reveal targets for future study. The transcriptome profiles of breast cancer stroma and normal breast stroma were compared to identify differentially expressed genes (DEGs). The method...

Analysis of influential factors of self-reported hearing loss deviation in young adults

BackgroundHearing loss is becoming more and more common in young adults. Many researches have utilized self-reported hearing conditions only to obtain the morbidity of hearing loss. Therefore, we decided to explore factors contributing to self-reported hearing loss deviation in young Chinese adults and compare the loss with audiometric results.MethodsWe examined the hearing...

Identifying Important Nodes in Complex Networks Based on Multiattribute Evaluation

Correspondence should be addressed to Jianpei Zhang; nc.ude.uebrh@iepnaijgnahz Received 13 February 2018; Accepted 16 April 2018; Published 31 May 2018 Academic Editor: Yang Tang Copyright © 2018 Hui Xu et al

Identifying Important Nodes in Complex Networks Based on Multiattribute Evaluation

Correspondence should be addressed to Jianpei Zhang; nc.ude.uebrh@iepnaijgnahz Received 13 February 2018; Accepted 16 April 2018; Published 31 May 2018 Academic Editor: Yang Tang Copyright © 2018 Hui Xu et al

Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells

© 2018 Hui Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Effect of Exogenous Alpha-B Crystallin on the Structures and Functions of Trabecular Meshwork Cells

© 2018 Hui Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the

Scalp metastases as first presentation of pulmonary adenocarcinomas: a case report

Scalp metastases as first presentation of pulmonary adenocarcinomas: a case report Qian Yu,1,2,* Smriti Subedi,1,2,* Yunlei Tong,1,2 Qing Wei,3 Hui Xu,1,2 Yao Wang,1,2 Yu Gong1,2 Yuling Shi1,2

NETO2 promotes invasion and metastasis of gastric cancer cells via activation of PI3K/Akt/NF-κB/Snail axis and predicts outcome of the patients

Aberrant expression of neuropilin and tolloid-like 2 (NETO2) has been observed during the progression of some human carcinomas. However, the expression pattern and clinical relevance of NETO2 in gastric cancer (GC) remain to be elucidated. In this study, we found that NETO2 expression was higher in GC tissues compared with paired non-cancerous tissues. Moreover, the expression of...

Detection of PRMT1 inhibitors with stopped flow fluorescence

, China AffiliationsDepartment of Pharmaceutical and Biomedical Sciences, University of Georgia, Athens, GA, 30602, USAKun Qian, Hui Xu & Y George Zheng AuthorsSearch for Kun Qian in:Nature Research ... journals • PubMed • Google Scholar Search for Hao Hu in:Nature Research journals • PubMed • Google Scholar Search for Hui Xu in:Nature Research journals • PubMed • Google Scholar Search for Y George Zheng

Composition and distribution of NSO compounds in two different shales at the early maturity stage characterized by negative ion electrospray ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry

Gas chromatography/mass spectrometry (GC/MS) can only analyze volatile molecular compounds, and it has limitations when applied to determine the complex components of crude oils and hydrocarbon source rocks. Based on Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR-MS) and GC/MS analyses, the molecular compositions of NSO compounds in extracts from the Permian...

On-shell gauge invariant three-point amplitudes

Assuming locality, Lorentz invariance and parity conservation we obtain a set of differential equations governing the 3-point interactions of massless bosons, which in turn determines the polynomial ring of these amplitudes. We derive all possible 3-point interactions for tensor fields with polarisations that have total symmetry and mixed symmetry under permutations of Lorentz...

Mathematical Modeling and Mechanism of VUV Photodegradation of H2S in the Absence of O2

Academic Editor: Juan M. Coronado Copyright © 2018 Jian-hui Xu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution ... this study are available from the corresponding author upon request. Conflicts of Interest The authors declare that they have no conflicts of interest. Authors’ Contributions Jian-hui Xu and Bin-bin Ding