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Significant predictors of medically diagnosed chronic obstructive pulmonary disease in patients with preserved ratio impaired spirometry: a 3-year cohort study

Preserved ratio impaired spirometry (PRISm) is an incompletely understood respiratory condition. We investigated the incidence and significant predictive factors of chronic obstructive pulmonary disease (COPD) in PRISm patients. From 11,922 subjects registered in the Korea National Health and Nutrition Examination Survey, never or light smokers, young subjects, and those already...

Association between Genetic Polymorphism of Multidrug Resistance 1 Gene and Sasang Constitutions

Multidrug resistance 1 (MDR1) is a gene that expresses P-glycoprotein (P-gp), a drug transporter protein. Genetic polymorphisms of MDR1 can be associated with Sasang constitutions because Sasang constitutional medicine (SCM) prescribes different drugs according to different constitutions. A Questionnaire for Sasang Constitution Classification II (QSCC II) was used to diagnose...

Association between Genetic Polymorphism of Multidrug Resistance 1 Gene and Sasang Constitutions

Multidrug resistance 1 (MDR1) is a gene that expresses P-glycoprotein (P-gp), a drug transporter protein. Genetic polymorphisms of MDR1 can be associated with Sasang constitutions because Sasang constitutional medicine (SCM) prescribes different drugs according to different constitutions. A Questionnaire for Sasang Constitution Classification II (QSCC II) was used to diagnose...

Video education versus face-to-face education on inhaler technique for patients with well-controlled or partly-controlled asthma: A phase IV, open-label, non-inferiority, multicenter, randomized, controlled trial

Chang from the Statistics Team of C&R Research Inc. for performing the statistical analyses. Author Contributions Conceptualization: Hye Jung Park, Sook Young Lee, Byoung Whui Choi. Data curation: Min ... Kwang Byun, Jae-Woo Kwon, Woo Kyung Kim, Dong-Ho Nahm, Myung-Goo Lee, Sang-Pyo Lee, Ji-Hyun Lee, Yi Yeong Jeong, You Sook Cho, Jeong-Hee Choi, Byoung Whui Choi. Formal analysis: Hye Jung Park, Min Kwang

Effect of S267F variant of NTCP on the patients with chronic hepatitis B

Sodium taurocholate cotransporting polypeptide (NTCP) was identified as an entry receptor for hepatitis B virus (HBV) infection. The substitution of serine at position 267 of NTCP with phenylalanine (S267F) is an Asian-specific variation that hampers HBV entry in vitro. In this study, we aimed to evaluate the prevalence of S267F polymorphism in Korean patients with chronic...

Effectiveness of proton pump inhibitor in unexplained chronic cough

Pharmaceutical Co., Ltd., Seoul, Korea. Author Contributions Conceptualization: Yoo Mi Park, Jie-Hyun Kim, Min Kwang Byun. Data curation: Hye Jung Park, Yoo Mi Park, Jie-Hyun Kim, Hye Sun Lee, Hyung Jung Kim ... , Chul Min Ahn, Min Kwang Byun. Formal analysis: Hye Jung Park, Yoo Mi Park, Hye Sun Lee, Min Kwang Byun. Funding acquisition: Min Kwang Byun. Investigation: Hye Jung Park, Yoo Mi Park, Hyung Jung Kim

Birt-Hogg-Dube syndrome prospectively detected by review of chest computed tomography scans

Purpose Birt-Hogg-Dube syndrome (BHD) is a rare disorder caused by mutations in the gene that encodes folliculin (FLCN) and is inherited in an autosomal dominant manner. BHD is commonly accompanied by fibrofolliculomas, renal tumors, multiple pulmonary cysts, and spontaneous pneumothorax. The aim of this study was to detect BHD prospectively in patients undergoing chest computed...

Corrigendum: Secreted tryptophanyl-tRNA synthetase as a primary defence system against infection

Kang Soyeon Ahn Chul-Ho Lee Jong Soo Lee Kyung-Soo Inn Mi-La Cho Sung-Hwan Park Kyunghee Park Hye Jung Park Jae-Hyun Lee Jung-Won Park Nam Hoon Kwon Hyunbo Shim Byung Woo Han Pilhan Kim Joo-Youn Lee