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Impact of Gold Nanoparticles on Testosterone Metabolism in Human Liver Microsomes

Gold nanoparticle (AuNP)-protein corona complexes can alter cytochrome P450 (CYP)-mediated testosterone (TST) metabolism by altering their physicochemical properties. We investigated the impact of NP size, surface chemistry, and protein corona in TST metabolism in pooled human liver microsomes (pHLM) employing 40 and 80 nm AuNP functionalized with branched polyethylenimine (BPEI...

Assessment of Gold Nanoparticles-Inhibited Cytochrome P450 3A4 Activity and Molecular Mechanisms Underlying Its Cellular Toxicity in Human Hepatocellular Carcinoma Cell Line C3A

Interactions of the 40 and 80 nm gold nanoparticles (AuNP) functionalized with cationic branched polyethylenimine (BPEI), anionic lipoic acid (LA), or neutral polyethylene glycol (PEG) with human hepatocellular carcinoma (HCC) cell line C3A have been investigated in the absence and presence of human plasma protein corona (PC). All bare (no PC) AuNP besides 80 nm LA-AuNP were...

Mechanism Underlying Green Discolouration of Myoglobin Induced by Atmospheric Pressure Plasma

In this study, we elucidated the mechanism underlying atmospheric pressure plasma (APP)-induced green discolouration of myoglobin. Green-coloured pigments are produced upon conversion of myoglobin into sulphmyoglobin, choleglobin, verdoheme, nitrihemin, or nitrimyoglobin. We exposed myoglobin dissolved in phosphate buffer to APP for 20 min and found a decrease in a* value...

Prevalence of extraintestinal manifestations in Korean inflammatory bowel disease patients

: Joongyub Lee. Writing ? original draft: Bo Ram Yang, Joongyub Lee. Writing ? review & editing: Jaeyoung Chun, Sang Hyun Joo. 10 / 13 11 / 13 12 / 13 1. Vavricka SR , Schoepfer A , Scharl M , Lakatos PL

Inhibition of poly-LacNAc biosynthesis with release of CMP-Neu5Ac feedback inhibition increases the sialylation of recombinant EPO produced in CHO cells

Daehak-ro, Yuseong-gu, Daejeon, 34134, Republic of KoreaMyung Jin Oh & Hyun Joo AnAsia-pacific Glycomics Reference Site, Daejeon, 34134, Republic of KoreaMyung Jin Oh & Hyun Joo AnDivision of Rheumatology ... • PubMed • Google Scholar Search for Myung Jin Oh in:Nature Research journals • PubMed • Google Scholar Search for Seung-Yeol Park in:Nature Research journals • PubMed • Google Scholar Search for Hyun Joo

Prognostic value of systemic inflammatory markers and development of a nomogram in breast cancer

) S1 Table. Raw data. (XLSX) Author Contributions Young Jin Suh, Hyun Joo Choi. Conceptualization: Uiju Cho, Hong Sik Park, So Young Im, Chang Young Yoo, Ji Han Jung, Data curation: Uiju Cho, So Young ... Im, Chang Young Yoo, Ji Han Jung, Hyun Joo Choi. Formal analysis: Uiju Cho, Hyun Joo Choi. Investigation: Uiju Cho, Hong Sik Park, So Young Im, Young Jin Suh, Hyun Joo Choi. Methodology: Uiju Cho

Application of the fragment molecular orbital method to discover novel natural products for prion disease

 & Hyun-Joo SohnDepartment of Biotechnology, Yonsei University, Seoul, 03722, KoreaXuemei Jin, Hocheol Lim & Kyoung Tai No AuthorsSearch for Jiwon Choi in:Nature Research journals • PubMed • Google Scholar ... in:Nature Research journals • PubMed • Google Scholar Search for Kyoung Tai No in:Nature Research journals • PubMed • Google Scholar Search for Hyun-Joo Sohn in:Nature Research journals • PubMed • Google

Landslide Susceptibility Assessment Using Frequency Ratio Technique with Iterative Random Sampling

Soo-Min Hong; rk.ca.sou@gnohmoos Received 17 April 2017; Revised 5 July 2017; Accepted 12 July 2017; Published 6 September 2017 Academic Editor: Eduard Llobet Copyright © 2017 Hyun-Joo Oh et al

Landslide Susceptibility Assessment Using Frequency Ratio Technique with Iterative Random Sampling

Soo-Min Hong; rk.ca.sou@gnohmoos Received 17 April 2017; Revised 5 July 2017; Accepted 12 July 2017; Published 6 September 2017 Academic Editor: Eduard Llobet Copyright © 2017 Hyun-Joo Oh et al

Glycomic Approach for Potential Biomarkers on Prostate Cancer: Profiling of N-Linked Glycans in Human Sera and pRNS Cell Lines

Disease Markers 0278-0240 Glycomic approach for potential biomarkers on prostate cancer: Profiling of N-linked glycans in human sera and pRNS cell lines Maria Lorna A. de Leoz 0 Hyun Joo An 0 Scott

Sulfisoxazole inhibits the secretion of small extracellular vesicles by targeting the endothelin receptor A

Lee 3 Jae Man Lee 3 Jae-Chul Lee 4 Jun-Goo Jee 5 Jong-Sup Bae 5 Taeg-Kyu Kwon 6 Keon-Wook Kang 7 Myeong-Seon Jeong 8 9 Joo-Eun Lee 9 Hyun-Suk Jung 9 Hyun-Joo Ro 10 Sangmi Jun 10 Wonku Kang 11 Seung-Yong

The association between hippocampal subfield volumes and education in cognitively normal older adults and amnestic mild cognitive impairment patients

The association between hippocampal subfield volumes and education in cognitively normal older adults and amnestic mild cognitive impairment patients Dong Woo Kang,1 Hyun Kook Lim,2 Soo-hyun Joo,1 Na ... (ww.tcpdf.org) hyun Kook lim 2 soo-hyun Joo 1 Na rae lee 1 chang Uk lee 1 education and total hippocampal volume in the trajectory of Alzheimer's disease (AD). However, the correlation between education and

Glycomic Approach for Potential Biomarkers on Prostate Cancer: Profiling of N-Linked Glycans in Human Sera and pRNS Cell Lines

Disease Markers 0278-0240 Glycomic approach for potential biomarkers on prostate cancer: Profiling of N-linked glycans in human sera and pRNS cell lines Maria Lorna A. de Leoz 4 Hyun Joo An 4 Scott

Functional Test Scales for Evaluating Cell-Based Therapies in Animal Models of Spinal Cord Injury

Recently, spinal cord researchers have focused on multifaceted approaches for the treatment of spinal cord injury (SCI). However, as there is no cure for the deficits produced by SCI, various therapeutic strategies have been examined using animal models. Due to the lack of standardized functional assessment tools for use in such models, it is important to choose a suitable animal...

Trends in the seroprevalence of Helicobacter pylori infection and its putative eradication rate over 18 years in Korea: A cross-sectional nationwide multicenter study

Contributions Conceptualization: Seon Hee Lim, Nayoung Kim. Data curation: Seon Hee Lim, Nayoung Kim, Sung Eun Kim, Gwang Ho Baik, Ju Yup Lee, Kyung Sik Park, Jeong Eun Shin, Hyun Joo Song, Dae-Seong Myung ... Baik, Ju Yup Lee, Kyung Sik Park, Jeong Eun Shin, Hyun Joo Song, Dae-Seong Myung, Suck Chei Choi, Hyun Jin Kim, Jeong Yoon Yim. Methodology: Seon Hee Lim, Sung Eun Kim, Jeong Yoon Yim. Resources: Jeong

Association between mental health status and bone mineral density: Analysis of the 2008-2010 Korea national health and nutrition examination survey

participated in the KNHANES. We also thank Kyungdo Han for statistical analyses. Author Contributions Conceptualization: Changtae Hahn, Soo-Hyun Joo, Jo-Eun Jeong, Tae-Suk Kim. Data curation: Changtae Hahn ... , Soo-Hyun Joo, Jo-Eun Jeong. Formal analysis: Changtae Hahn, Ji Hoon Oh, Tae-Suk Kim. Funding acquisition: Changtae Hahn, Tae-Suk Kim. Investigation: Changtae Hahn, Soo-Hyun Joo, Jo-Eun Jeong, Jeong

Incidence and factors associated with mortality in 2,476 patients with variant angina in Korea

Yong Lee AuthorsSearch for Hack-Lyoung Kim in:Nature Research journals • PubMed • Google ScholarSearch for Jayeun Kim in:Nature Research journals • PubMed • Google ScholarSearch for Hyun Joo Kim

Finding the Primary Care Providers in the Specialist-Dominant Primary Care Setting of Korea: A Cluster Analysis

Objective This study aimed to identify private clinics that have a potential to perform the role of primary care providers (PCPs) in a primary care setting in Korea where private specialists are dominant. Methods The 2013 National Patient Sample claim data of Health Insurance Review and Assessment Service in Korea was used. Two-step cluster analysis was performed using...

Optimal Acquisition Number for Hepatic Shear Wave Velocity Measurements in Children

Objective To investigate the minimum optimal acquisition number of hepatic shear wave velocities (SWVs) on ultrasound elastography in children. Materials and Methods We prospectively performed hepatic supersonic shear wave elastography in children of four groups (group A-C, healthy children, group A with 0–5 years old; group B with 6–10 years old; group C with 11–18 years old...