Advanced search    

Search: authors:"Inho Jo"

10 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Tonsil-derived mesenchymal stem cell-embedded in situ crosslinkable gelatin hydrogel therapy recovers postmenopausal osteoporosis through bone regeneration

our system, as well as to examine the molecular mechanism underlying the therapeutic effects of TMSC-GHH. Author Contributions Conceptualization: Ki Dong Park, Inho Jo. Data curation: Kyung-Ha Ryu ... , Yoon Jeong Park. Formal analysis: Yoon Shin Park, Yunki Lee. Funding acquisition: Inho Jo. Investigation: Da Hyeon Choi, Yoon Jeong Park, Inho Jo. Methodology: Gyungah Kim, Yoon Shin Park. Project

Therapeutic potential of tonsil-derived mesenchymal stem cells in dextran sulfate sodium-induced experimental murine colitis

, the increasing doses of TMSC did not further decrease in DAI scores. (PDF) Author Contributions Conceptualization: Yeonsil Yu, Eun Mi Song, Sung-Ae Jung, Inho Jo. Data curation: Yeonsil Yu, Eun Mi ... Song, Yang-Hee Joo, Sung-Ae Jung, Inho Jo. Formal analysis: Yeonsil Yu, Yang-Hee Joo. Funding acquisition: Yeonsil Yu, Sung-Ae Jung. Investigation: Yeonsil Yu, Eun Mi Song, Ko Eun Lee, Yang-Hee Joo

The Green Tea Component (-)-Epigallocatechin-3-Gallate Sensitizes Primary Endothelial Cells to Arsenite-Induced Apoptosis by Decreasing c-Jun N-Terminal Kinase-Mediated Catalase Activity

The green tea component (-)-epigallocatechin-3-gallate (EGCG) has been shown to sensitize many different types of cancer cells to anticancer drug-induced apoptosis, although it protects against non-cancerous primary cells against toxicity from certain conditions such as exposure to arsenic (As) or ultraviolet irradiation. Here, we found that EGCG promotes As-induced toxicity of...

Study design and methods of the Ansan Geriatric Study (AGE study)

Background The overall objective of the Ansan Geriatric Study (AGE study) was to describe the prevalence, incidence, and related risk factors for geriatric diseases in elderly Koreans. Methods/Design The AGE study was designed as a population-based prospective cohort study on health, aging, and common geriatric diseases of elderly Koreans aged 60 to 84 years. The inception cohort...

Presenilin 1/γ-Secretase Is Associated with Cadmium-Induced E-Cadherin Cleavage and COX-2 Gene Expression in T47D Breast Cancer Cells

Cadmium is a heavy metal that has multiple toxic effects on human health and has been classified as a human carcinogen. E-cadherin is a major target of cadmium; however, the roles of E-cadherin and cadmium and the mechanisms of tumor progression remain to be defined. Here, we demonstrate that cadmium increases E-cadherin processing via a γ-secretase in the T47D breast cancer cell...

The transgenerational impact of benzo(a)pyrene on murine male fertility

BACKGROUND Benzo(a)pyrene (BaP) is an endocrine toxicant that is widely distributed in the environment. The adverse effects of BaP on fertility are well documented, however its effects on fertility in the subsequent generations are not known. We aimed to investigate the transgenerational effects of BaP on male fertility in mice.

Long-Term Enzymatic and Phenotypic Correction in the Phenylketonuria Mouse Model by Adeno-Associated Virus Vector-Mediated Gene Transfer

Phenylketonuria (PKU) is an autosomal recessive metabolic disorder caused by a deficiency of phenylalanine hydroxylase (PAH). The accumulation of phenylalanine leads to severe mental and psychomotor retardation, and hypopigmentation of skin and hair. Low-phenylalanine diet therapy can prevent irreversible damage if instituted from birth. However, poor compliance with the strict...

No difference in stroke knowledge between Korean adherents to traditional and western medicine – the AGE study: an epidemiological study

Background Effective stroke intervention and risk reduction depend on the general public's awareness and knowledge of stroke. In Korea, where both traditional Oriental medicine and Western medicine are practiced, estimates of the general public's awareness and knowledge of stroke are poor. The present study sought to describe the inception cohort of the Ansan Geriatric Study (AGE...

Morbidity and related factors among elderly people in South Korea: results from the Ansan Geriatric (AGE) cohort study

Background A thorough examination of the morbidity and comorbidity profiles among the elderly and an evaluation of the related factors are required to improve the delivery of health care to the elderly and to estimate the cost of that care. In South Korea where the aged population is rapidly increasing, however, to date only one study using a limited sample (84 subjects) has...

The molecular basis of phenylketonuria in Koreans

Phenylketonuria (PKU) is an inborn error of metabolism that results from a deficiency of phenylalanine hydroxylase (PAH). We characterized the PAH mutations of 79 independent Korean patients with PKU or hyperphenylalaninemia. PAH nucleotide sequence analysis revealed 39 different mutations, including ten novel mutations. The novel mutations consisted of nine missense mutations...