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The Association between Eating Traits and Weight Change after a Lifestyle Intervention in People with Type 2 Diabetes Mellitus

. Welschen,2,4 Petra J. Elders,2,4 Giel Nijpels,2,4 and Femke Rutters1,2 1Department of Epidemiology and Biostatistics, VU Medical Centre, Amsterdam, Netherlands 2Amsterdam Public Health Research Institute ... Rutters researched the data and wrote the manuscript. Joline W. Beulens, Laura M. Welschen, and Petra J. Elders reviewed and edited the manuscript. Giel Nijpels and Femke Rutters conceived and designed the

The Association between Eating Traits and Weight Change after a Lifestyle Intervention in People with Type 2 Diabetes Mellitus

. Welschen,2,4 Petra J. Elders,2,4 Giel Nijpels,2,4 and Femke Rutters1,2 1Department of Epidemiology and Biostatistics, VU Medical Centre, Amsterdam, Netherlands 2Amsterdam Public Health Research Institute ... Rutters researched the data and wrote the manuscript. Joline W. Beulens, Laura M. Welschen, and Petra J. Elders reviewed and edited the manuscript. Giel Nijpels and Femke Rutters conceived and designed the

Driving restrictions for Dutch patients with an implantable cardioverter defibrillator

Background Dutch patients with an implantable cardioverter defibrillator (ICD) are restricted from driving for two months after implantation or shocks. This requires significant lifestyle adjustments and is one of the primary concerns of ICD patients. Previous studies indicated that compliance with the driving restrictions is poor, but insight in socio-demographic, clinical and...

Remote monitoring and follow-up of cardiovascular implantable electronic devices in the Netherlands

: CC de Cock, MD PhD, Department of Cardiology , VUmc, Amsterdam ; J Elders, RN MA, Department of Cardiology, Canisius Wilhelmina Hospital , Nijmegen ; NM van Hemel, MD PhD, Prof Em, Utrecht University

Erythrocyte insulin binding studies in growth hormone deficiency

Growth hormone (GH) is known to induce insulin resistance, although the mechanism of this action is poorly understood. To investigate whether GH or somatomedin (SM) may alter insulin binding at the cell surface receptor, we have studied in GH deficient (GHD) children the effect of acute and long-term GH therapy on erythrocyte insulin receptor binding (IRB). Fifteen GHD, ages 2-13...

Correlation of metabolic parameters with high and low affinity insulin receptor binding in leprechaunism (L)

In vitro binding of 125I-insulin to erythrocyte and fibroblast surface receptors (IRB) was studied in a 3-year-old girl with L, her parents, and controls. At low insulin concentrations (0.1-2 ng/ml), both erythrocyte and fibroblast IRB were decreased relative to controls. Scatchard analysis of IRB showed a typical curvilinear profile for controls, but a linear function in the L...

461 ROLE OF DIETARY PROTEIN AND AMINO ACIDS IN THE MODULATION OF PLASMA SOMATOMEDIN ACTIVITY IN RATS

The mechanism of growth retardation in many nutritional deficiency states has not been delineated. Somatomedin (SM) is depressed after prolonged fasting or in severe malnutrition despite elevated growth hormone (GH) concentrations, suggesting both nutrition and GH may act as modulators of SM. We have studied the effects of varying concentrations of dietary protein (2.5, 5, 10, 20...

600 EFFECT OF CRANIAL RADIATION DOSE ON GROWTH HORMONE RESPONSE TO ARGININE AND INSULIN INFUSION

The prolonged survival of children with acute lymphocytic leukemia (ALL) has been accompanied by an increase in the incidence of central nervous system involvement. Radiation to the skull in doses of 2000-2400 rads, in conjunction with intrathecal methotrexate, has been used to prolong systemic remission and to reduce the incidence of central nervous system involvement in...

Alteration of Cartilage Glycosaminoglycan Protein Acceptor by Somatomedin and Cortisol

Medical Sciences were supported by USPHS Grants AM15901 and CA13907 , Grant AM 17550. 32. Requests for reprints should be addressed to: M. J . Elders , M.D.. Department of Pediatrics, University of Arkansas

891 ETIOLOGY OF FIRST DAY HYPOCALCEMIA (FDH): ROLE OF PTH AND CALCITONIN?

To determine the potential role of endocrine factors in the pathogenesis of FDH, we have measured plasma PTH, calcitonin (CT) and calcium (Ca) concentrations (conc.) in 38 infants with documented hypocalcemia (Ca ≤7.5 mg/dl) and in known high risk groups of FDH including premature infants (n=51), asphyxiated newborns (25), and infants of diabetic mothers (IDM, n=22). Sequential...

Reduced insulin binding in a large kindred with severe diabetic retinopathy

Specific insulin binding to erythrocyte receptors (IRB) has previously been reported to be unaltered in children and adolescents with insulin dependent diabetes mellitus (Ped. 66:385, 1980). However, we report here that five insulin dependent, ketosis-resistant juvenile diabetics from the same kinship have a significant reduction in the percent IRB (normal 8.32±2.71 vs 4.72±0.84...