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Search: authors:"Jae Myoung Suh"

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Atf4 Regulates Obesity, Glucose Homeostasis, and Energy Expenditure

Jin Seo Edgardo S. Fortuno III Jae Myoung Suh Drew Stenesen Wei Tang Elizabeth J. Parks Christopher M. Adams Tim Townes Jonathan M. Graff OBJECTIVE-We evaluate a potential role of activating

An RGS-Containing Sorting Nexin Controls Drosophila Lifespan

The pursuit of eternal youth has existed for centuries and recent data indicate that fat-storing tissues control lifespan. In a D. melanogaster fat body insertional mutagenic enhancer trap screen designed to isolate genes that control longevity, we identified a regulator of G protein signaling (RGS) domain containing sorting nexin, termed snazarus (sorting nexin lazarus, snz...

Treatment with 4-Methylpyrazole Modulated Stellate Cells and Natural Killer Cells and Ameliorated Liver Fibrosis in Mice

Background & Aims Accumulating evidence suggests that retinol and its metabolites are closely associated with liver fibrogenesis. Recently, we demonstrated that genetic ablation of alcohol dehydrogenase 3 (ADH3), a retinol metabolizing gene that is expressed in hepatic stellate cells (HSCs) and natural killer (NK) cells, attenuated liver fibrosis in mice. In the current study, we...

Synergistic actions of FGF2 and bone marrow transplantation mitigate radiation-induced intestinal injury

Hyemi Shin 4 Jeanny Kwon 3 Jae Myoung Suh 1 4 0 Division of Biological Warfare Preparedness and Response, Armed Forces Medical Research Institute , Daejeon , Republic of Korea 1 Graduate School of