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Sarcopenic obesity and cognitive performance

University , Boca raton, Fl, UsA , USA 2 James e galvin PowerdbyTCPDF( stephanie Chrisphonte 1 Background: Sarcopenia and obesity both negatively impact health including cognitive function. Their

Lewy Body Dementia Association’s Research Centers of Excellence Program: Inaugural Meeting Proceedings

National Institutes of Health (NIH) and the Michael J. Fox Foundation. James E Galvin has received grant support from NIH, Michael J Fox Foundation, Harry T. Mangurian Foundation, Lewy Body Dementia

Cognitive impairment in Parkinson’s disease: a report from a multidisciplinary symposium on unmet needs and future directions to maintain cognitive health

Beth A. Vernaleo 10 Richard Camicioli 11 Nabila Dahodwala 12 Roseanne D. Dobkin 13 Terry Ellis 14 James E. Galvin 15 Connie Marras 16 Jerri Edwards 17 Julie Fields 19 Robyn Golden 0 Jason Karlawish 1

Longitudinal Associations between Physical and Cognitive Performance among Community-Dwelling Older Adults

To assess the directionality of the association between physical and cognitive decline in later life, we compared patterns of decline in performance across groups defined by baseline presence of cognitive and/or physical impairment [none (n = 217); physical only (n = 169); cognitive only (n = 158), or both (n = 220)] in a large sample of participants in a cognitive aging study at...

Lewy body dementia: the impact on patients and caregivers

Lewy body dementia (LBD) is the second most common neurodegenerative dementia in older adults, yet there remains a delay in diagnosis that limits healthcare providers’ ability to maximize therapeutic outcomes and enhance patient and caregiver quality of life. The impact of LBD on patients includes limiting the potential exposure to medications that may cause adverse outcomes, and...

The Neurotoxicity of DOPAL: Behavioral and Stereological Evidence for Its Role in Parkinson Disease Pathogenesis

Background The etiology of Parkinson disease (PD) has yet to be fully elucidated. We examined the consequences of injections of 3,4-dihydroxyphenylacetaldehyde (DOPAL), a toxic metabolite of dopamine, into the substantia nigra of rats on motor behavior and neuronal survival. Methods/Principal Findings A total of 800 nl/rat of DOPAL (1 µg/200 nl) was injected stereotaxically into...