Advanced search    

Search: authors:"Jan Baak"

4 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Intratumor Heterogeneity of K-Ras and p53 Mutations among Human Colorectal Adenomas Containing Early Cancer

The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor heterogeneity of the mutational status of the k‐ras oncogene and of the p53 oncosuppressor gene during the adenoma–carcinoma sequence by investigating 26 human colorectal adenomas containing early cancer. An intratumor...

Intratumor Heterogeneity of K-Ras and p53 Mutations among Human Colorectal Adenomas Containing Early Cancer

The molecular pathways and the timing of genetic events during human colorectal carcinogenesis are still not fully understood. We have addressed the intratumor heterogeneity of the mutational status of the k‐ras oncogene and of the p53 oncosuppressor gene during the adenoma–carcinoma sequence by investigating 26 human colorectal adenomas containing early cancer. An intratumor...

Factors that influence persistence or recurrence of high-grade squamous intraepithelial lesion with positive margins after the loop electrosurgical excision procedure: a retrospective study

Background In 5–20 % of patients with cervical high-grade squamous intraepithelial lesion (HSIL), a positive margin after the loop electrosurgical excision procedure (LEEP) is associated with persistence/recurrence, but the prognostic value of other clinico-pathological factors is less clear. Methods Among 4336 patients with HSIL who underwent an initial LEEP, 275 (6 %) had HSIL...

Centromeric chromosomal translocations show tissue-specific differences between squamous cell carcinomas and adenocarcinomas

, University of Technology, Dresden, Germany AffiliationsDepartment of Pathology, VU University Medical Center, Amsterdam, The NetherlandsMario Hermsen, Marta Alonso Guervós, Jan Baak, Paul van Diest & Gerrit ... • PubMed • Google ScholarSearch for Simone Tænzer in:Nature Research journals • PubMed • Google ScholarSearch for Ulrike Koerner in:Nature Research journals • PubMed • Google ScholarSearch for Jan Baak