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Thickness of retina and choroid in the elderly population and its association with Complement Factor H polymorphism: KLoSHA Eye study

-Kyung Ryoo, Jeeyun Ahn. Funding acquisition: Jiyeong Seo, Ji Won Han, Ki Woong Kim, Se Joon Woo. Investigation: Ji Won Han, Ki Woong Kim, Se Joon Woo. Methodology: Na-Kyung Ryoo, Seong Joon Ahn ... . Project administration: Na-Kyung Ryoo, Jiyeong Seo, Ji Won Han, Ki Woong Kim, Se Joon Woo. Resources: Ji Won Han, Ki Woong Kim. 12 / 15 Supervision: Kyu Hyung Park, Ki Woong Kim, Se Joon Woo. Validation

Test-Retest Reliability and Concurrent Validity of a Single Tri-Axial Accelerometer-Based Gait Analysis in Older Adults with Normal Cognition

Objective We investigated the concurrent validity and test-retest reliability of spatio-temporal gait parameters measured with a single tri-axial accelerometer (TAA), determined the optimal number of steps required for obtaining acceptable levels of reliability, and compared the validity and reliability of the estimated gait parameters across the three reference axes of the TAA...

Efficacy of the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (USMART) program among patients with mild cognitive impairment: a randomized controlled crossover trial

BackgroundSpaced retrieval training (SRT) is a nonpharmacological intervention for mild cognitive impairment (MCI) and dementia that trains the learning and retention of target information by recalling it over increasingly long intervals. We recently developed the Ubiquitous Spaced Retrieval-based Memory Advancement and Rehabilitation Training (USMART) program as a convenient...

Effects of lifetime cumulative ginseng intake on cognitive function in late life

BackgroundWe investigated the effects of lifetime cumulative ginseng intake on cognitive function in a community-dwelling population-based prospective cohort of Korean elders.MethodsCommunity-dwelling elders (N = 6422; mean age = 70.2 ± 6.9 years, education = 8.0 ± 5.3 years, female = 56.8%) from the Korean Longitudinal Study on Cognitive Aging and Dementia were included. Among...

Multidimensional Geriatric Prognostic Index, Based on a Geriatric Assessment, for Long-Term Survival in Older Adults in Korea

The patient´s survival estimate is important for clinical decision-making, especially in frail patients with multimorbidities. We aimed to develop a multidimensional geriatric prognosis index (GPI) for 3- and 5-year mortality in community-dwelling elderly and to validate the GPI in a separate hospital-based population. The GPI was constructed using data for 988 participants in...

Prevalence and Outcomes of Frailty in Korean Elderly Population: Comparisons of a Multidimensional Frailty Index with Two Phenotype Models

Background Frailty is related to adverse outcomes in the elderly. However, current status and clinical significance of frailty have not been evaluated for the Korean elderly population. We aimed to investigate the usefulness of established frailty criteria for community-dwelling Korean elderly. We also tried to develop and validate a new frailty index based on a multidimensional...

Development of a Screening Algorithm for Alzheimer's Disease Using Categorical Verbal Fluency

We developed a weighted composite score of the categorical verbal fluency test (CVFT) that can more easily and widely screen Alzheimer's disease (AD) than the mini-mental status examination (MMSE). We administered the CVFT using animal category and MMSE to 423 community-dwelling mild probable AD patients and their age- and gender-matched cognitively normal controls. To enhance...

Cough in the Elderly Population: Relationships with Multiple Comorbidity

BackgroundThe epidemiology of cough in the elderly population has not been studied comprehensively. The present study aimed to investigate the epidemiology of cough in a community elderly population, particularly in relation with their comorbidity. MethodsA cross-sectional analysis was performed using a baseline dataset from the Korean Longitudinal Study on Health and Aging, a...