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Attribution of the Last Glacial Maximum climate formation

To better understand what determines the Last Glacial Maximum (LGM) cold and dry climate, a suite of numerical experiments with the Nanjing University of Information Science and Technology Earth System Model version 1 are conducted to assess the relative contributions of individual external forcings, including greenhouse gases (GHGs), ice sheets (IS), land-sea configuration (LSC...

Hemodynamic impacts of flow diverter devices on the ophthalmic artery

Flow diverter devices are increasingly used for endovascular treatment of internal carotid artery aneurysms. Treatment of ophthalmic segment aneurysms with flow diverter devices also includes coverage of the ophthalmic artery but may result in complications. It is unclear, however, whether these devices mechanically block blood flow in the ophthalmic artery. Also unclear is the...

Hypocoagulation induced by broad-spectrum antibiotics in extensive burn patients

VKD Vitamin K deficiency vWF von Willebrand factor Jian Liu, Yiqing Liu, and Shenjun Liu joint as first authors. Jian Liu, Yiqing Liu, and Shenjun Liu contributed equally to this report

Detecting large extra dimensions with optomechanical levitated sensors

Many experiments have been conducted to detect hypothetical large extra dimensions from sub-millimeter to solar system separations. However, direct evidence for such extra dimensions has not been found. Here we present a scheme to test the gravitational law in 4 + 2 dimensions at micron separations by optomechanical methods. We demonstrate the feasibility of the normal mode...

Cobalt single atoms anchored on N-doped ultrathin carbon nanosheets for selective transfer hydrogenation of nitroarenes

affiliations Huining Li (李会宁)Changyan Cao (曹昌燕)Jian Liu (刘剑)Yang Shi (施杨)Rui Si (司锐)Lin Gu (谷林)Weiguo Song (宋卫国) Articles First Online: 12 April 2019 Abstract Selective transfer hydrogenation of

Spiradiclis karstana (Rubiaceae), a new species from Yunnan, China

Spiradiclis karstana, a new species of Spiradiclis (Rubiaceae) collected from Yunnan, China, is described for the first time. It is morphologically close to S. jingxiensis, but differs from the latter mainly by its inflorescences with 5–9 flowers, its 1.5–2.4 mm long peduncles, its stipules shorter than 1 mm and the 5–12 pairs of secondary veins. The conservation status is...

Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion

BackgroundCyclin-dependent kinase-like 1 (CDKL1) is a member of the cell division control protein 2-related serine–threonine protein kinase family. It is known to occur in various malignant tumors, but its role in neuroblastoma (NB) remains unclear.MethodsWe constructed a CDKL1-silenced NB cell strain (SH-SY5Y) and used real-time PCR and western blotting to confirm the silencing...

Transgenic Cry1Ac cotton does not affect the development and fecundity of Chrysoperla carnea

Contributions Conceptualization: Ruifeng Ding, Deying Ma, Ahtam Uwais, Dongmei Wang, Jian Liu, Yao Xu. Data curation: Ruifeng Ding, Yao Xu. Formal analysis: Ruifeng Ding, Dongmei Wang, Haobin Li. Funding ... acquisition: Jian Liu. Investigation: Ruifeng Ding, Haiqiang Li. Methodology: Ruifeng Ding, Ahtam Uwais, Dongmei Wang, Yao Xu, Haobin Li, Haiqiang Li. Project administration: Jian Liu, Yao Xu. Resources

Drivers of reduced ENSO variability in mid-Holocene in a coupled model

The drivers of El Niño–Southern Oscillation (ENSO) intensity change during the mid-Holocene (MH) are investigated through employing a coupled model that exhibits excellent performance in simulating the present-day ENSO behaviors. The model shows a 28% decrease in ENSO intensity in the MH simulation compared to the pre-industrial (PI) simulation, showing an agreement with the...

Elevated BNP caused by recombinant human interleukin-11 treatment in patients with chemotherapy-induced thrombocytopenia

Thrombocytopenia is a condition characterized by abnormally low levels of thrombocytes and often induced by chemotherapy. Recombinant human interleukin-11 (rhIL-11) is a cytokine that can stimulate thrombopoiesis and is commonly used to treat thrombocytopenia. We observed the side effects of rhIL-11 in 24 leukemia patients with chemotherapy-induced thrombocytopenia. To determine...

The Core Eudicot Boom Registered in Myanmar Amber

A perfect flower in a mid-Cretaceous (early Cenomanian) Myanmar amber is described as Lijinganthus revoluta gen. et sp. nov. The fossil flower is actinomorphic and pentamerous, including calyx, corolla, stamens, and gynoecium. The sepals are tiny, while the petals are large and revolute. The stamens are dorsifixed, filamentous, and each has a longitudinally dehiscing...

Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs

Redox-responsive hyaluronic acid-functionalized graphene oxide nanosheets for targeted delivery of water-insoluble cancer drugs Jian Liu,1,2 Doudou Zhang,1,2 Shu Lian,1,2 Junxia Zheng,1,2 Bifei Li

Cavity optomechanical spectroscopy constraints chameleon dark energy scenarios

The chameleon scalar field is a matter-coupled dark energy candidate with the screening mechanisms. In the present paper,we propose a quantum cavity optomechanical scheme to detect the possible signature of chameleons via the optical pump-probe spectroscopy. Compare to the previous experiment the sensitivity can be improved by the using of electrostatic shield and a pump-probe...

Effects of vehicle gap changes on fuel economy and emission performance of the traffic flow in the ACC strategy

: Tao Yang. Data curation: Jian Liu. Formal analysis: Xiaoqing Qin. Investigation: Xiuhai Li, Shaowei Yu. Methodology: Xiuhai Li, Shaowei Yu. Validation: Shaowei Yu. Writing ? original draft: Xiuhai

Minimal uranium accumulation in lymphoid tissues following an oral 60-day uranyl acetate exposure in male and female C57BL/6J mice

1P42ES025589-01A1 and the UNM Clinical and Translational Science Center Grant UL1TR001449. Author Contributions Conceptualization: Ke Jian Liu, Scott W. Burchiel. Formal analysis: Alicia M. Bolt, Sebastian ... Medina, Fredine T. Lauer. Funding acquisition: Ke Jian Liu, Scott W. Burchiel. Investigation: Alicia M. Bolt, Sebastian Medina, Fredine T. Lauer, Abdul-Mehdi Ali. Methodology: Alicia M. Bolt, Sebastian

The expression level and prognostic value of HIPK3 among non-small-cell lung cancer patients in China

Honggang Ke,2 Jian Liu,3 Jianguo Zhang1 1Department of Pathology, Affiliated Hospital of Nantong University, Nantong, Jiangsu, China; 2Department of Thoracic Surgery, Affiliated Hospital of Nantong ... Editor who approved publication: Dr Jianmin Xu Yifei Liu,1,* Li Qian,1,* Juanjuan Yang,1 Hua Huang,1 Jia Feng,1 Xiaoli Li,1 Tingting Bian,1 Honggang Ke,2 Jian Liu,3 Jianguo Zhang1

Cancer Characteristic Gene Selection via Sample Learning Based on Deep Sparse Filtering

Identification of characteristic genes associated with specific biological processes of different cancers could provide insights into the underlying cancer genetics and cancer prognostic assessment. It is of critical importance to select such characteristic genes effectively. In this paper, a novel unsupervised characteristic gene selection method based on sample learning and...

Tribological study of N-containing borate derivatives and their synergistic antioxidation effects with T531

Two N-containing borates, BTES and BMES, were synthesized with dodecyl phenol, 2-(N-containing heterocyclic) ethan-1-ol, boric acid, and dibutylamine, and their tribological properties in rapeseed oil (RSO) were investigated using a four-ball tester. The results showed that the load-carrying ability (PB value) of RSO can be improved by 40.9% and 67.9%, respectively, when using 0...

Classification of Daily Activities for the Elderly Using Wearable Sensors

Academic Editor: Qingjun Liu Copyright © 2017 Jian Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and

Classification of Daily Activities for the Elderly Using Wearable Sensors

Academic Editor: Qingjun Liu Copyright © 2017 Jian Liu et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and