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15 papers found.
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Temperature field simulations during selective laser melting process based on fully threaded tree

Selective laser melting (SLM) is a promising technique for additive manufacturing. During SLM of metallic powder, the temperature field and thermal history are important to understand physical phenomena involved. The purpose of this study is to simulate the temperature field during the SLM process of a hollow cylinder shape part based on a fully threaded tree (FTT) technique, and...

Risk of severe hematologic toxicities in cancer patients treated with PARP inhibitors: a meta-analysis of randomized controlled trials

Risk of severe hematologic toxicities in cancer patients treated with PARP inhibitors: a meta-analysis of randomized controlled trials Jian xin Zhou,1,* Li jin Feng,2,* Xi Zhang3 1Department of

Phase field study on crystal orientation effects in eutectoid phase transformation

In this present work, a multi-phase field model was used to simulate the eutectoid transformation process, and on the basis of the nucleation model that was previously proposed by our research team, anisotropic and orientation relationship models were introduced to study the growth mechanism of the pearlite lamellae with anisotropy. It was found that the growth direction of the...

Multi-scale coupling simulation in directional solidification of superalloy based on cellular automaton-finite difference method

Casting microstructure evolution is difficult to describe quantitatively by only a separate simulation of dendrite scale or grain scale, and the numerical simulation of these two scales is difficult to render compatible. A three-dimensional cellular automaton model couplling both dendritic scale and grain scale is developed to simulate the microstructure evolution of the nickel...

Effects of hot isostatic pressing temperature on casting shrinkage densification and microstructure of Ti6Al4V alloy

Die & Mould Technology, Huazhong University of Science and Technology , Wuhan 430074, China 2. Beijing Institute of Aeronautical Materials, Aviation Industry of China , Beijing 100095 , China 1 Jian-xin ... Zhou The Ti6Al4V alloy castings were produced by the investment casting process, and the hot isostatic pressing (HIP) was used to remove shrinkage from castings. The processing pressure and holding time

Optimal design of feeding system in steel casting by constrained optimization algorithms based on InteCAST

The traditional foundry industry has developed rapidly in recently years due to advancements in computer technology. Modifying and designing the feeding system has become more convenient with the help of the casting software, InteCAST. A common method of designing a feeding system is to first design the initial systems, run simulations with casting software, analyze the feedback...

Agreement of measured and calculated serum osmolality during the infusion of mannitol or hypertonic saline in patients after craniotomy: a prospective, double-blinded, randomised controlled trial

Background Mannitol and hypertonic saline are used to ameliorate brain edema and intracranial hypertension during and after craniotomy. We hypothesized that the agreement of measured and calculated serum osmolality during the infusion of hypertonic saline would be better than mannitol. The objective was to determine the accuracy of serum osmolality estimation by different...

Ultrasound measurement of optic nerve diameter and optic nerve sheath diameter in healthy Chinese adults

-Xin Zhou 0 0 Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University , No 6, TiantanXili, Dongcheng District, Beijing 100050 , China 1 Department of Ultrasonography

Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy in critically ill patients: a systematic review

Jian-Xin Zhou 0 0 Department of Critical Care Medicine, Beijing Tiantan Hospital, Capital Medical University , Beijing 100050 , China 1 Surgical Intensive Care Unit, Fujian Provincial Clinical College

Incidence, Risk Factors and Consequences of Emergence Agitation in Adult Patients after Elective Craniotomy for Brain Tumor: A Prospective Cohort Study

Emergence agitation is a frequent complication that can have serious consequences during recovery from general anesthesia. However, agitation has been poorly investigated in patients after craniotomy. In this prospective cohort study, adult patients were enrolled after elective craniotomy for brain tumor. The sedation-agitation scale was evaluated during the first 12 hours after...

Use of dexmedetomidine for prophylactic analgesia and sedation in delayed extubation patients after craniotomy: a study protocol and statistical analysis plan for a randomized controlled trial

Background Pain and agitation are common in patients after craniotomy. They can result in tachycardia, hypertension, immunosuppression, increased catecholamine production and increased oxygen consumption. Dexmedetomidine, an alpha-2 agonist, provides adequate sedation without respiratory depression, while facilitating frequent neurological evaluation. Methods/design The study is...

Real-Time Continuous Glucose Monitoring Shows High Accuracy within 6 Hours after Sensor Calibration: A Prospective Study

Accurate and timely glucose monitoring is essential in intensive care units. Real-time continuous glucose monitoring system (CGMS) has been advocated for many years to improve glycemic management in critically ill patients. In order to determine the effect of calibration time on the accuracy of CGMS, real-time subcutaneous CGMS was used in 18 critically ill patients. CGMS sensor...

Use of cerebral state index to predict long-term unconsciousness in patients after elective craniotomy with delay recovery

Background The major difficulty in postoperative care in patients after craniotomy is to distinguish the intracranial deficits from the residual effect of general anesthesia. In present study, we used cerebral state index (CSI) monitoring in patients after craniotomy with delayed recovery, and evaluated the prediction probability of CSI for long-term postoperative unconsciousness...

Functional Val66Met polymorphism of Brain-derived neurotrophic factor in type 2 diabetes with depression in Han Chinese subjects

Background Brain-derived neurotrophic factor (BDNF) has been implicated in the pathogenesis of major depression. Individuals with type 2 diabetes (T2DM) have a high prevalence of major depression and low levels of BDNF. We therefore explored whether the BDNF Val66Met polymorphism is associated with co-morbid depression and whether depression affects the serum levels of BDNF in a...

Factors influencing delayed extubation after infratentorial craniotomy for tumour resection: a prospective cohort study of 800 patients in a Chinese neurosurgical centre

Objectives To investigate prospectively the rate of, and factors influencing, delayed extubation following infratentorial craniotomy in a Chinese neurosurgical centre.